Epidemiological features of viral hepatitis C in the Tomsk region
Introduction. Despite the great advances made in the field of virology and their diagnostics, a number of difficulties affect improvements in the control and elimination of hepatitis C virus (HCV) infection at present. New cases of HCV infection still occur worldwide, including Tomsk Region (TR). Th...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Sankt-Peterburg : NIIÈM imeni Pastera
2025-07-01
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| Series: | Инфекция и иммунитет |
| Subjects: | |
| Online Access: | https://iimmun.ru/iimm/article/viewFile/17688/2178 |
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| Summary: | Introduction. Despite the great advances made in the field of virology and their diagnostics, a number of difficulties affect improvements in the control and elimination of hepatitis C virus (HCV) infection at present. New cases of HCV infection still occur worldwide, including Tomsk Region (TR). The aim of the study was to analyze the epidemiological situation with regard to acute and chronic forms of HCV in adults and children for the period 2022–2023, and the structure of morbidity in TR.
Materials and methods. The features of the HCV epidemic process were assessed using official data presented in the State Report “On the state of sanitary and epidemiological well-being of the population in the Russian Federation in 2023”, statistical reporting form No. 2, federal statistical surveillance form No. 65 “Information on chronic viral hepatitis” form 065 for the period of 2023, quarterly reports of regions to the Ministry of Health of the Russian Federation within the framework of the implementation of measures aimed at combating HCV infection in 2021–2030.
Results. In TR, stable incidence rates of first-time detected forms of chronic viral hepatitis have been registered over the last years: in 2023 — 18.82 cases of chronic hepatitis C per 100 thousand population, in the population of children — 11.2 cases per 100 thousand population. Indicators of HCV morbidity in the TR indicate a tendency towards the spread of HCV infection in all age groups with an increase in the age limit. Genotypic diversity of HCV infection in the TR in 2023 is represented by subtypes 1a, 1b, 2, 3a/3b. The planned coverage of antiviral therapy in 2024 cannot significantly affect the epidemiologic situation on HCV in TR and achieve the results of elimination by 2030 and requires annual increase of funding.
Conclusion. The incidence rate of HCV infection in the TR is 1.7 times lower than the all-Russian one. Low level of HCV prevalence in the pediatric population in the TR made it possible to carry out micro-elimination of HCV among children. Insufficient level of HCV genotypes determination requires increasing the coverage of genotyping for epidemiologic surveillance in each region. |
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| ISSN: | 2220-7619 2313-7398 |