BRD4 Silencing Protects Angiotensin II-Induced Cardiac Hypertrophy by Inhibiting TLR4/NF-κB and Activating Nrf2-HO-1 Pathways

BRD4 Silencing Protects Angiotensin II-Induced Cardiac Hypertrophy by Inhibiting TLR4/NF-κB and Activating Nrf2-HO-1 Pathways

Background. Heart failure is a critical health problem worldwide, and cardiac hypertrophy is an important characteristic of heart failure. Bromodomain-containing protein 4 (BRD4) is involved in various cellular processes, including cardiac hypertrophy. This study aimed to investigate the mechanism u...

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Bibliographic Details
Main Authors:	Ming Fang, Jun Luo, Xi Zhu, Yingbiao Wu, Xinming Li
Format:	Article
Language:	English
Published:	Wiley 2022-01-01
Series:	Cardiology Research and Practice
Online Access:	http://dx.doi.org/10.1155/2022/8372707
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