Perspectives and Future Directions of Anticoagulant Therapy in Coronary Artery Disease Patients

Antiplatelet agents are routinely used to treat patients with chronic atherosclerotic coronary artery disease. Treatment with the addition of a low dose of rivaroxaban as dual-pathway inhibition (DPI) decreases ischaemic events at the expense of increased bleeding. At present, the balance between th...

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Bibliographic Details
Main Authors: Maki Komiyama, Gheorghe-Andrei Dan, Koji Hasegawa
Format: Article
Language:English
Published: Radcliffe Medical Media 2023-04-01
Series:European Cardiology Review
Online Access:https://www.ecrjournal.com/articleindex/ecr.2022.66
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Summary:Antiplatelet agents are routinely used to treat patients with chronic atherosclerotic coronary artery disease. Treatment with the addition of a low dose of rivaroxaban as dual-pathway inhibition (DPI) decreases ischaemic events at the expense of increased bleeding. At present, the balance between thrombotic and bleeding risks must be carefully weighed up when considering DPI. However, with the introduction of activated coagulation factor XI inhibitors, which have fewer bleeding effects, the use of DPI in patients with atherosclerotic cardiovascular diseases could be extended.
ISSN:1758-3756
1758-3764