Successful Treatment of Bladder Fungus Ball Due to Candida auris With Systemic/Local Amphotericin B and Surgical Excision

Fungal infections in the urine are rare in healthy individuals but can occur in patients with diabetes, immunosuppression, urinary catheterization, prolonged hospital stays, and the use of broad-spectrum antibiotics. The most common strain is Candida, with Candida albicans being the most prevalent....

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Main Authors: Yağmur Erkol Yilmaz, Merve Havan, Eda Eyduran, Nilay Penezoğlu, Duygu Öcal, Serap Teber, Ergin Çiftçi, Yakup Tarkan Soygür, Tanıl Kendirli
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/crpe/9741756
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author Yağmur Erkol Yilmaz
Merve Havan
Eda Eyduran
Nilay Penezoğlu
Duygu Öcal
Serap Teber
Ergin Çiftçi
Yakup Tarkan Soygür
Tanıl Kendirli
author_facet Yağmur Erkol Yilmaz
Merve Havan
Eda Eyduran
Nilay Penezoğlu
Duygu Öcal
Serap Teber
Ergin Çiftçi
Yakup Tarkan Soygür
Tanıl Kendirli
author_sort Yağmur Erkol Yilmaz
collection DOAJ
description Fungal infections in the urine are rare in healthy individuals but can occur in patients with diabetes, immunosuppression, urinary catheterization, prolonged hospital stays, and the use of broad-spectrum antibiotics. The most common strain is Candida, with Candida albicans being the most prevalent. Candida auris is a new emerged and severe, contagious species of Candida family especially in critically ill patients. We present a case of a 17-year-old male with neuromyelitis optica spectrum disorder who developed a fungus ball in the bladder. Despite multiple antibiotic therapies, persistent fevers led to the diagnosis of Candida auris and the detection of a fungus ball in the bladder. The patient was successfully treated with caspofungin, cystoscopy for total excision of the fungus ball, and intravesical liposomal amphotericin B. This case underscores the importance of early diagnosis and treatment of fungus balls to prevent complications such as obstructive complications and fungal urosepsis. In conclusion, identifying risk factors, such as immune dysregulation, prolonged PICU stay, mechanical ventilation, urinary catheter, and antibiotic use, is crucial in managing such cases.
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issn 2090-6811
language English
publishDate 2025-01-01
publisher Wiley
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series Case Reports in Pediatrics
spelling doaj-art-61287e9a554047fc9c8a360de02ed11c2025-08-20T02:25:12ZengWileyCase Reports in Pediatrics2090-68112025-01-01202510.1155/crpe/9741756Successful Treatment of Bladder Fungus Ball Due to Candida auris With Systemic/Local Amphotericin B and Surgical ExcisionYağmur Erkol Yilmaz0Merve Havan1Eda Eyduran2Nilay Penezoğlu3Duygu Öcal4Serap Teber5Ergin Çiftçi6Yakup Tarkan Soygür7Tanıl Kendirli8Department of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of Medical MicrobiologyDepartment of PediatricsDepartment of PediatricsDepartment of UrologyDepartment of PediatricsFungal infections in the urine are rare in healthy individuals but can occur in patients with diabetes, immunosuppression, urinary catheterization, prolonged hospital stays, and the use of broad-spectrum antibiotics. The most common strain is Candida, with Candida albicans being the most prevalent. Candida auris is a new emerged and severe, contagious species of Candida family especially in critically ill patients. We present a case of a 17-year-old male with neuromyelitis optica spectrum disorder who developed a fungus ball in the bladder. Despite multiple antibiotic therapies, persistent fevers led to the diagnosis of Candida auris and the detection of a fungus ball in the bladder. The patient was successfully treated with caspofungin, cystoscopy for total excision of the fungus ball, and intravesical liposomal amphotericin B. This case underscores the importance of early diagnosis and treatment of fungus balls to prevent complications such as obstructive complications and fungal urosepsis. In conclusion, identifying risk factors, such as immune dysregulation, prolonged PICU stay, mechanical ventilation, urinary catheter, and antibiotic use, is crucial in managing such cases.http://dx.doi.org/10.1155/crpe/9741756
spellingShingle Yağmur Erkol Yilmaz
Merve Havan
Eda Eyduran
Nilay Penezoğlu
Duygu Öcal
Serap Teber
Ergin Çiftçi
Yakup Tarkan Soygür
Tanıl Kendirli
Successful Treatment of Bladder Fungus Ball Due to Candida auris With Systemic/Local Amphotericin B and Surgical Excision
Case Reports in Pediatrics
title Successful Treatment of Bladder Fungus Ball Due to Candida auris With Systemic/Local Amphotericin B and Surgical Excision
title_full Successful Treatment of Bladder Fungus Ball Due to Candida auris With Systemic/Local Amphotericin B and Surgical Excision
title_fullStr Successful Treatment of Bladder Fungus Ball Due to Candida auris With Systemic/Local Amphotericin B and Surgical Excision
title_full_unstemmed Successful Treatment of Bladder Fungus Ball Due to Candida auris With Systemic/Local Amphotericin B and Surgical Excision
title_short Successful Treatment of Bladder Fungus Ball Due to Candida auris With Systemic/Local Amphotericin B and Surgical Excision
title_sort successful treatment of bladder fungus ball due to candida auris with systemic local amphotericin b and surgical excision
url http://dx.doi.org/10.1155/crpe/9741756
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