Characterization of Pulmonary Vein Dimensions Using High-Definition 64-Slice Computed Tomography prior to Radiofrequency Catheter Ablation for Atrial Fibrillation

Background. Contrast-enhanced computed tomography is commonly acquired before radiofrequency catheter ablation (RFCA) for atrial fibrillation (AFib) to guide the procedure. We analyzed pulmonary vein (PV) ostial diameter and volumes on a high-definition 64-slice CT (HDCT) scanner in patients with AF...

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Main Authors: Catherine Gebhard, Nazmi Krasniqi, Barbara E. Stähli, Bernd Klaeser, Tobias A. Fuchs, Jelena R. Ghadri, Laurent Haegeli, Thomas F. Lüscher, Philipp A. Kaufmann, Firat Duru
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Cardiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2014/179632
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author Catherine Gebhard
Nazmi Krasniqi
Barbara E. Stähli
Bernd Klaeser
Tobias A. Fuchs
Jelena R. Ghadri
Laurent Haegeli
Thomas F. Lüscher
Philipp A. Kaufmann
Firat Duru
author_facet Catherine Gebhard
Nazmi Krasniqi
Barbara E. Stähli
Bernd Klaeser
Tobias A. Fuchs
Jelena R. Ghadri
Laurent Haegeli
Thomas F. Lüscher
Philipp A. Kaufmann
Firat Duru
author_sort Catherine Gebhard
collection DOAJ
description Background. Contrast-enhanced computed tomography is commonly acquired before radiofrequency catheter ablation (RFCA) for atrial fibrillation (AFib) to guide the procedure. We analyzed pulmonary vein (PV) ostial diameter and volumes on a high-definition 64-slice CT (HDCT) scanner in patients with AFib prior to RFCA. Methods and Results. This retrospective study included 50 patients (mean age 60.2 ± 11.4 years, 30 males) undergoing cardiac HDCT scanning before RFCA for drug refractory AFib and 50 age-, BMI-, and sex-matched controls with normal sinus rhythm undergoing HDCT. PV ostial diameter and volume were measured and calculated using a semiautomatic calliper tool. Total ostial PV volume was significantly increased in patients with AFib as compared to controls (P<0.005). Similarly, total ostial PV diameter was significantly increased in AFib compared to controls (P<0.001). In AFib, the largest PV volume and diameters were measured in right superior PV (P<0.05 versus controls). The difference in PV volume between patients and controls was most pronounced in right superior PVs (P=0.015). Right middle PVs were found more often in patients with AFib (16/50; 32%) than in normal subjects (7/50; 14%). Conclusion. Enlargement of PV ostial area and enlargement of volume are frequent findings in patients with drug refractory AFib. These parameters may add to the risk stratification for AFib recurrence following RFCA.
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spelling doaj-art-612766e5511444dc8c2dcb0e23e49fd22025-02-03T01:30:46ZengWileyCardiology Research and Practice2090-80162090-05972014-01-01201410.1155/2014/179632179632Characterization of Pulmonary Vein Dimensions Using High-Definition 64-Slice Computed Tomography prior to Radiofrequency Catheter Ablation for Atrial FibrillationCatherine Gebhard0Nazmi Krasniqi1Barbara E. Stähli2Bernd Klaeser3Tobias A. Fuchs4Jelena R. Ghadri5Laurent Haegeli6Thomas F. Lüscher7Philipp A. Kaufmann8Firat Duru9Department of Cardiology, Cardiovascular Center, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, SwitzerlandDepartment of Cardiology, Cardiovascular Center, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, SwitzerlandDepartment of Cardiology, Cardiovascular Center, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, SwitzerlandDepartment of Radiology, Cardiac Imaging, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, SwitzerlandDepartment of Radiology, Cardiac Imaging, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, SwitzerlandDepartment of Cardiology, Cardiovascular Center, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, SwitzerlandDepartment of Cardiology, Cardiovascular Center, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, SwitzerlandDepartment of Cardiology, Cardiovascular Center, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, SwitzerlandDepartment of Radiology, Cardiac Imaging, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, SwitzerlandDepartment of Cardiology, Cardiovascular Center, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, SwitzerlandBackground. Contrast-enhanced computed tomography is commonly acquired before radiofrequency catheter ablation (RFCA) for atrial fibrillation (AFib) to guide the procedure. We analyzed pulmonary vein (PV) ostial diameter and volumes on a high-definition 64-slice CT (HDCT) scanner in patients with AFib prior to RFCA. Methods and Results. This retrospective study included 50 patients (mean age 60.2 ± 11.4 years, 30 males) undergoing cardiac HDCT scanning before RFCA for drug refractory AFib and 50 age-, BMI-, and sex-matched controls with normal sinus rhythm undergoing HDCT. PV ostial diameter and volume were measured and calculated using a semiautomatic calliper tool. Total ostial PV volume was significantly increased in patients with AFib as compared to controls (P<0.005). Similarly, total ostial PV diameter was significantly increased in AFib compared to controls (P<0.001). In AFib, the largest PV volume and diameters were measured in right superior PV (P<0.05 versus controls). The difference in PV volume between patients and controls was most pronounced in right superior PVs (P=0.015). Right middle PVs were found more often in patients with AFib (16/50; 32%) than in normal subjects (7/50; 14%). Conclusion. Enlargement of PV ostial area and enlargement of volume are frequent findings in patients with drug refractory AFib. These parameters may add to the risk stratification for AFib recurrence following RFCA.http://dx.doi.org/10.1155/2014/179632
spellingShingle Catherine Gebhard
Nazmi Krasniqi
Barbara E. Stähli
Bernd Klaeser
Tobias A. Fuchs
Jelena R. Ghadri
Laurent Haegeli
Thomas F. Lüscher
Philipp A. Kaufmann
Firat Duru
Characterization of Pulmonary Vein Dimensions Using High-Definition 64-Slice Computed Tomography prior to Radiofrequency Catheter Ablation for Atrial Fibrillation
Cardiology Research and Practice
title Characterization of Pulmonary Vein Dimensions Using High-Definition 64-Slice Computed Tomography prior to Radiofrequency Catheter Ablation for Atrial Fibrillation
title_full Characterization of Pulmonary Vein Dimensions Using High-Definition 64-Slice Computed Tomography prior to Radiofrequency Catheter Ablation for Atrial Fibrillation
title_fullStr Characterization of Pulmonary Vein Dimensions Using High-Definition 64-Slice Computed Tomography prior to Radiofrequency Catheter Ablation for Atrial Fibrillation
title_full_unstemmed Characterization of Pulmonary Vein Dimensions Using High-Definition 64-Slice Computed Tomography prior to Radiofrequency Catheter Ablation for Atrial Fibrillation
title_short Characterization of Pulmonary Vein Dimensions Using High-Definition 64-Slice Computed Tomography prior to Radiofrequency Catheter Ablation for Atrial Fibrillation
title_sort characterization of pulmonary vein dimensions using high definition 64 slice computed tomography prior to radiofrequency catheter ablation for atrial fibrillation
url http://dx.doi.org/10.1155/2014/179632
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