Effect of Nasal Obstructive Disorders on Sinonasal Symptoms in Children with Different Levels of Bronchial Asthma Control
Allergic rhinitis (AR) and allergic rhinosinusitis (ARS) are typical upper airway pathologies (UAP) in children with bronchial asthma (BA) frequently accompanied with nasal obstructive diseases (NOD). In order to establish the effect of NOD on correlations between nasal and synonasal symptoms with c...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/2018/4835823 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832547010582937600 |
|---|---|
| author | T. I. Eliseeva S. V. Krasilnikova N. A. Geppe S. Yu. Babaev E. V. Tush O. V. Khaletskaya D. Yu. Ovsyannikov I. I. Balabolkin S. K. Ignatov N. I. Kubysheva |
| author_facet | T. I. Eliseeva S. V. Krasilnikova N. A. Geppe S. Yu. Babaev E. V. Tush O. V. Khaletskaya D. Yu. Ovsyannikov I. I. Balabolkin S. K. Ignatov N. I. Kubysheva |
| author_sort | T. I. Eliseeva |
| collection | DOAJ |
| description | Allergic rhinitis (AR) and allergic rhinosinusitis (ARS) are typical upper airway pathologies (UAP) in children with bronchial asthma (BA) frequently accompanied with nasal obstructive diseases (NOD). In order to establish the effect of NOD on correlations between nasal and synonasal symptoms with clinical assessments of asthma control, 82 children, 9.8 [8.9; 10.7] years old, with atopic BA were assessed using ACQ-5 for the BA control level, TNSS for nasal symptoms, and SNOT-20 for synonasal quality of life in combination with rhinovideoendoscopy for NOD. All patients had AR/ARS; in 76.3% (63/82) of children, UAP had a multimorbid character with the presence of NOD. Significant correlations were found between ACQ-5 and TNSS (R=0.40, p<0.0001) and ACQ-5 and SNOT-20 (R=0.42, p<0.0001). Correlations between TNSS/ACQ-5 and SNOT-20/ACQ-5 were higher in patients who do not have a combination of AR/ARS with NOD (R=0.67, p=0.0012; R=0.50, p=0.022, resp.) than in patients who have AR/ARS combined with NOD (R=0.30, p=0.015; R=0.26, p=0.04, resp.). Thus, the association of BA control level with the expression of nasal and synonasal symptoms is higher in children who do not have multimorbid UAP. |
| format | Article |
| id | doaj-art-6117e80abef14890965ff899adbdf1ed |
| institution | Kabale University |
| issn | 1198-2241 1916-7245 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-6117e80abef14890965ff899adbdf1ed2025-02-03T06:46:17ZengWileyCanadian Respiratory Journal1198-22411916-72452018-01-01201810.1155/2018/48358234835823Effect of Nasal Obstructive Disorders on Sinonasal Symptoms in Children with Different Levels of Bronchial Asthma ControlT. I. Eliseeva0S. V. Krasilnikova1N. A. Geppe2S. Yu. Babaev3E. V. Tush4O. V. Khaletskaya5D. Yu. Ovsyannikov6I. I. Balabolkin7S. K. Ignatov8N. I. Kubysheva9Department of Hospital Pediatrics and Department of ENT Diseases, Nizhny Novgorod State Medical Academy, 10/1 Minin and Pozharsky Square, Nizhny Novgorod 603005, RussiaDepartment of Hospital Pediatrics and Department of ENT Diseases, Nizhny Novgorod State Medical Academy, 10/1 Minin and Pozharsky Square, Nizhny Novgorod 603005, RussiaDepartment of Children Diseases, I.M. Sechenov First Moscow State Medical University, 8 Bld. 2 Trubetskaya St., Moscow 119991, RussiaDepartment of Hospital Pediatrics and Department of ENT Diseases, Nizhny Novgorod State Medical Academy, 10/1 Minin and Pozharsky Square, Nizhny Novgorod 603005, RussiaDepartment of Hospital Pediatrics and Department of ENT Diseases, Nizhny Novgorod State Medical Academy, 10/1 Minin and Pozharsky Square, Nizhny Novgorod 603005, RussiaDepartment of Hospital Pediatrics and Department of ENT Diseases, Nizhny Novgorod State Medical Academy, 10/1 Minin and Pozharsky Square, Nizhny Novgorod 603005, RussiaDepartment of Pediatrics, Medical Institute, Peoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., Moscow 117198, RussiaRussian Academy of Sciences, Department of Pulmonology and Allergology, National Scientific and Practical Centre of Children’s Health, Lomonosovsky Avenue, Moscow 119991, RussiaDepartment of Chemistry, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin Avenue, Nizhny Novgorod 603950, RussiaMedical Informatics Research Laboratory of the Higher School of Information Technologies and Information Systems, Kazan Federal University, 18 Kremlyovskaya St., Kazan, Republic of Tatarstan 420008, RussiaAllergic rhinitis (AR) and allergic rhinosinusitis (ARS) are typical upper airway pathologies (UAP) in children with bronchial asthma (BA) frequently accompanied with nasal obstructive diseases (NOD). In order to establish the effect of NOD on correlations between nasal and synonasal symptoms with clinical assessments of asthma control, 82 children, 9.8 [8.9; 10.7] years old, with atopic BA were assessed using ACQ-5 for the BA control level, TNSS for nasal symptoms, and SNOT-20 for synonasal quality of life in combination with rhinovideoendoscopy for NOD. All patients had AR/ARS; in 76.3% (63/82) of children, UAP had a multimorbid character with the presence of NOD. Significant correlations were found between ACQ-5 and TNSS (R=0.40, p<0.0001) and ACQ-5 and SNOT-20 (R=0.42, p<0.0001). Correlations between TNSS/ACQ-5 and SNOT-20/ACQ-5 were higher in patients who do not have a combination of AR/ARS with NOD (R=0.67, p=0.0012; R=0.50, p=0.022, resp.) than in patients who have AR/ARS combined with NOD (R=0.30, p=0.015; R=0.26, p=0.04, resp.). Thus, the association of BA control level with the expression of nasal and synonasal symptoms is higher in children who do not have multimorbid UAP.http://dx.doi.org/10.1155/2018/4835823 |
| spellingShingle | T. I. Eliseeva S. V. Krasilnikova N. A. Geppe S. Yu. Babaev E. V. Tush O. V. Khaletskaya D. Yu. Ovsyannikov I. I. Balabolkin S. K. Ignatov N. I. Kubysheva Effect of Nasal Obstructive Disorders on Sinonasal Symptoms in Children with Different Levels of Bronchial Asthma Control Canadian Respiratory Journal |
| title | Effect of Nasal Obstructive Disorders on Sinonasal Symptoms in Children with Different Levels of Bronchial Asthma Control |
| title_full | Effect of Nasal Obstructive Disorders on Sinonasal Symptoms in Children with Different Levels of Bronchial Asthma Control |
| title_fullStr | Effect of Nasal Obstructive Disorders on Sinonasal Symptoms in Children with Different Levels of Bronchial Asthma Control |
| title_full_unstemmed | Effect of Nasal Obstructive Disorders on Sinonasal Symptoms in Children with Different Levels of Bronchial Asthma Control |
| title_short | Effect of Nasal Obstructive Disorders on Sinonasal Symptoms in Children with Different Levels of Bronchial Asthma Control |
| title_sort | effect of nasal obstructive disorders on sinonasal symptoms in children with different levels of bronchial asthma control |
| url | http://dx.doi.org/10.1155/2018/4835823 |
| work_keys_str_mv | AT tieliseeva effectofnasalobstructivedisordersonsinonasalsymptomsinchildrenwithdifferentlevelsofbronchialasthmacontrol AT svkrasilnikova effectofnasalobstructivedisordersonsinonasalsymptomsinchildrenwithdifferentlevelsofbronchialasthmacontrol AT nageppe effectofnasalobstructivedisordersonsinonasalsymptomsinchildrenwithdifferentlevelsofbronchialasthmacontrol AT syubabaev effectofnasalobstructivedisordersonsinonasalsymptomsinchildrenwithdifferentlevelsofbronchialasthmacontrol AT evtush effectofnasalobstructivedisordersonsinonasalsymptomsinchildrenwithdifferentlevelsofbronchialasthmacontrol AT ovkhaletskaya effectofnasalobstructivedisordersonsinonasalsymptomsinchildrenwithdifferentlevelsofbronchialasthmacontrol AT dyuovsyannikov effectofnasalobstructivedisordersonsinonasalsymptomsinchildrenwithdifferentlevelsofbronchialasthmacontrol AT iibalabolkin effectofnasalobstructivedisordersonsinonasalsymptomsinchildrenwithdifferentlevelsofbronchialasthmacontrol AT skignatov effectofnasalobstructivedisordersonsinonasalsymptomsinchildrenwithdifferentlevelsofbronchialasthmacontrol AT nikubysheva effectofnasalobstructivedisordersonsinonasalsymptomsinchildrenwithdifferentlevelsofbronchialasthmacontrol |