Zinc Influences the Efficacy of Betulinic Acid Treatment and Radiotherapy in Breast Cancer Cells

Zinc Influences the Efficacy of Betulinic Acid Treatment and Radiotherapy in Breast Cancer Cells

The trace element zinc influences a number of biological reactions, including cell growth, apoptosis, and DNA damage, which affect tumor therapy. The natural compound betulinic acid (BA) and its derivatives are known for their antiviral, antibacterial, and antitumor effects. Previous studies show th...

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Bibliographic Details
Main Authors: Antje Güttler, Elisa Darnstaedt, Danny Knobloch-Sperlich, Marina Petrenko, Jacqueline Kessler, Ivo Grosse, Dirk Vordermark, Matthias Bache
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Antioxidants
Subjects:
breast cancer
betulinic acid
zinc
ROS
radiation
radiosensitivity
Online Access:https://www.mdpi.com/2076-3921/13/11/1299
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