Antibiotic resistance patterns in nosocomial infections: preliminary data from Hospital of Al-Hoceima, Morocco
Introduction: Nosocomial infections or healthcare-associated infections (HCAIs) represent a public health problem. The burden of antibiotic resistance in these infections is still unclear in Morocco. The objective of this study was to describe antibiotic susceptibility of the main bacteria responsi...
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The Journal of Infection in Developing Countries
2023-09-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/17454 |
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| author | Mostapha Abourrich Nadira Mourabit Samia Boussa Mohammed Ghalit Rachida Elbarghmi Nabia Guerrouj Fatima Aich Asiya Khermach Hossain El Ouargh |
| author_facet | Mostapha Abourrich Nadira Mourabit Samia Boussa Mohammed Ghalit Rachida Elbarghmi Nabia Guerrouj Fatima Aich Asiya Khermach Hossain El Ouargh |
| author_sort | Mostapha Abourrich |
| collection | DOAJ |
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Introduction: Nosocomial infections or healthcare-associated infections (HCAIs) represent a public health problem. The burden of antibiotic resistance in these infections is still unclear in Morocco. The objective of this study was to describe antibiotic susceptibility of the main bacteria responsible for nosocomial infections in order to propose prevention measures.
Methodology: Data were collected from 1519 laboratory records including hospital inpatients suspected of nosocomial infections in Mohamed V Hospital of Al-Hoceima between January 2016 and December 2020. The data were analyzed using SPSS software version 25.
Results: Bacteriological test samples included 65.5% of urine, 27.2% of pleural fluid, 4.5% of pus, and 2.8% of protected distal swab. Two hundred and twenty-seven (15%) samples were culture-positive. The bacteria isolated were mainly enterobacteria (Escherichia coli, 43.6% and Klebsiella pneumoniae, 13%), non-fermentative Gram-negative bacteria (Pseudomonas aeruginosa, 10.8%), and Staphylococcus aureus (24.3%). Extended spectrum beta-lactamases (ESBLs)-producing Enterobacteriaceae represented 25.4% and those resistant to other families of antibiotics accounted for 12.5%. In our study, we reported 17% ESBL producers among urinary infections. Methicillin-resistant Staphylococcus aureus accounted for 22.2%. Pseudomonas aeruginosa that were resistant to ticarcillin, ceftazidime, and imipenem represented 29% of the cases.
Conclusions: Our results showed a higher frequency of resistance. A microbiological surveillance system is highly needed to identify bacterial niches in the hospital environment at Mohamed V Hospital.
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| format | Article |
| id | doaj-art-610ee7e3453d4e3ba208fcc42a520bff |
| institution | DOAJ |
| issn | 1972-2680 |
| language | English |
| publishDate | 2023-09-01 |
| publisher | The Journal of Infection in Developing Countries |
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| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-610ee7e3453d4e3ba208fcc42a520bff2025-08-20T02:57:21ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802023-09-01170910.3855/jidc.17454Antibiotic resistance patterns in nosocomial infections: preliminary data from Hospital of Al-Hoceima, MoroccoMostapha Abourrich0Nadira Mourabit1Samia Boussa2Mohammed Ghalit3Rachida Elbarghmi4Nabia Guerrouj5Fatima Aich6Asiya Khermach7Hossain El Ouargh8Environmental Health and Hospital Hygiene Department. Provincial Health Delegation of Al-Hoceima, MoroccoEnvironmental Technologies, Biotechnology and Valorization of Bio-Resources Team, Faculty of Sciences and Techniques of Al-Hoceima, Abdelmalek Essaadi University, Tetouan, MoroccoHigher Institute of Nursing Professions and Health Techniques, Marrakech, MoroccoLaboratory of Applied Chemistry and Environment, Faculty of Sciences, University Mohamed First, Oujda, MoroccoResearch Team of Water and Environmental Management, Laboratory of Applied Sciences, National School of Applied Sciences Al-Hoceima, Abdelmalek Essaadi University, Tetouan, MoroccoMedical Bacteriology Department, Medical Laboratory of the Provincial Hospital of Al-Hoceima, MoroccoCommittee for the Control of Nosocomial Infections of the Provincial Hospital of Al-Hoceima, MoroccoMedical laboratory of the Provincial Hospital of Al-Hoceima, MoroccoResearch Team of Water and Environmental Management, Laboratory of Applied Sciences, National School of Applied Sciences Al-Hoceima, Abdelmalek Essaadi University, Tetouan, Morocco Introduction: Nosocomial infections or healthcare-associated infections (HCAIs) represent a public health problem. The burden of antibiotic resistance in these infections is still unclear in Morocco. The objective of this study was to describe antibiotic susceptibility of the main bacteria responsible for nosocomial infections in order to propose prevention measures. Methodology: Data were collected from 1519 laboratory records including hospital inpatients suspected of nosocomial infections in Mohamed V Hospital of Al-Hoceima between January 2016 and December 2020. The data were analyzed using SPSS software version 25. Results: Bacteriological test samples included 65.5% of urine, 27.2% of pleural fluid, 4.5% of pus, and 2.8% of protected distal swab. Two hundred and twenty-seven (15%) samples were culture-positive. The bacteria isolated were mainly enterobacteria (Escherichia coli, 43.6% and Klebsiella pneumoniae, 13%), non-fermentative Gram-negative bacteria (Pseudomonas aeruginosa, 10.8%), and Staphylococcus aureus (24.3%). Extended spectrum beta-lactamases (ESBLs)-producing Enterobacteriaceae represented 25.4% and those resistant to other families of antibiotics accounted for 12.5%. In our study, we reported 17% ESBL producers among urinary infections. Methicillin-resistant Staphylococcus aureus accounted for 22.2%. Pseudomonas aeruginosa that were resistant to ticarcillin, ceftazidime, and imipenem represented 29% of the cases. Conclusions: Our results showed a higher frequency of resistance. A microbiological surveillance system is highly needed to identify bacterial niches in the hospital environment at Mohamed V Hospital. https://jidc.org/index.php/journal/article/view/17454resistancehospitalenvironmentMorocconosocomial infection |
| spellingShingle | Mostapha Abourrich Nadira Mourabit Samia Boussa Mohammed Ghalit Rachida Elbarghmi Nabia Guerrouj Fatima Aich Asiya Khermach Hossain El Ouargh Antibiotic resistance patterns in nosocomial infections: preliminary data from Hospital of Al-Hoceima, Morocco Journal of Infection in Developing Countries resistance hospital environment Morocco nosocomial infection |
| title | Antibiotic resistance patterns in nosocomial infections: preliminary data from Hospital of Al-Hoceima, Morocco |
| title_full | Antibiotic resistance patterns in nosocomial infections: preliminary data from Hospital of Al-Hoceima, Morocco |
| title_fullStr | Antibiotic resistance patterns in nosocomial infections: preliminary data from Hospital of Al-Hoceima, Morocco |
| title_full_unstemmed | Antibiotic resistance patterns in nosocomial infections: preliminary data from Hospital of Al-Hoceima, Morocco |
| title_short | Antibiotic resistance patterns in nosocomial infections: preliminary data from Hospital of Al-Hoceima, Morocco |
| title_sort | antibiotic resistance patterns in nosocomial infections preliminary data from hospital of al hoceima morocco |
| topic | resistance hospital environment Morocco nosocomial infection |
| url | https://jidc.org/index.php/journal/article/view/17454 |
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