Multi-Omics analysis and in vitro validation reveal diagnostic and therapeutic roles of novel hub genes in ovarian cancer

Multi-Omics analysis and in vitro validation reveal diagnostic and therapeutic roles of novel hub genes in ovarian cancer

Abstract Ovarian cancer (OC) remains a highly lethal gynecologic malignancy due to late diagnosis and limited therapeutic options. In this study, we aimed to identify and functionally validate novel hub genes associated with OC progression. We integrated four GEO microarray datasets (GSE54388, GSE40...

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Bibliographic Details
Main Authors: Jianmin Wang, Guanghui Song, Lili Xing
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Hereditas
Subjects:
OC
Hub genes
Biomarker
Therapeutic target
Online Access:https://doi.org/10.1186/s41065-025-00535-z
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