The effect of antipsychotic-induced extrapyramidal disorders on patient’s compliance with schizophrenia (a clinical case)
Extrapyramidal disorders are common adverse events in antipsychotic therapy. However, their diagnosis is difficult due to broad differential diagnosis, and often their specific clinical variant is not recognized, and timely intervention is not performed, which leads to severe patient suffering. This...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2022-01-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/4598 |
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| author | E. G. Rahim E. G. Kornetova A. A. Goncharova A. N. Кornetov A. V. Semke |
| author_facet | E. G. Rahim E. G. Kornetova A. A. Goncharova A. N. Кornetov A. V. Semke |
| author_sort | E. G. Rahim |
| collection | DOAJ |
| description | Extrapyramidal disorders are common adverse events in antipsychotic therapy. However, their diagnosis is difficult due to broad differential diagnosis, and often their specific clinical variant is not recognized, and timely intervention is not performed, which leads to severe patient suffering. This affects the quality of life of patients with schizophrenia and leads to their refusal to receive therapy, which aggravates the course of the disease. The article presents a clinical case of a 33-year-old patient at a psychiatric hospital with schizophrenia combined with such rare severe extrapyramidal disorders as antipsychotic-induced tardive dyskinesia and tardive dystonia.The diagnosis was carried out in accordance with the criteria of the International Classification of Diseases, Tenth Revision (ICD-10). The intensity of clinical manifestations was assessed using the Positive and Negative Syndrome Scale (PANSS), the Abnormal Involuntary Movement Scale (AIMS), and the Barnes Akathisia Rating Scale (BARS). Compliance was assessed using the Method for Measuring Medication Adherence in Psychiatry. Detailed differential diagnosis of tardive dyskinesia and tardive dystonia with akathisia and Huntington’s disease was presented. Substantiated treatment strategy and positive clinical dynamics with increased compliance were described. |
| format | Article |
| id | doaj-art-60fd0de7bb6a4a9bbd62dc2f14fb67e9 |
| institution | Kabale University |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-60fd0de7bb6a4a9bbd62dc2f14fb67e92025-08-20T04:00:10ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842022-01-0120421121710.20538/1682-0363-2021-4-211-2172857The effect of antipsychotic-induced extrapyramidal disorders on patient’s compliance with schizophrenia (a clinical case)E. G. Rahim0E. G. Kornetova1A. A. Goncharova2A. N. Кornetov3A. V. Semke4Mental Health Research Institute, Tomsk National Research Medical Center (NRMC), Russian Academy of SciencesMental Health Research Institute, Tomsk National Research Medical Center (NRMC), Russian Academy of Sciences; Siberian State Medical University (SSMU)Mental Health Research Institute, Tomsk National Research Medical Center (NRMC), Russian Academy of SciencesSiberian State Medical University (SSMU)Mental Health Research Institute, Tomsk National Research Medical Center (NRMC), Russian Academy of SciencesExtrapyramidal disorders are common adverse events in antipsychotic therapy. However, their diagnosis is difficult due to broad differential diagnosis, and often their specific clinical variant is not recognized, and timely intervention is not performed, which leads to severe patient suffering. This affects the quality of life of patients with schizophrenia and leads to their refusal to receive therapy, which aggravates the course of the disease. The article presents a clinical case of a 33-year-old patient at a psychiatric hospital with schizophrenia combined with such rare severe extrapyramidal disorders as antipsychotic-induced tardive dyskinesia and tardive dystonia.The diagnosis was carried out in accordance with the criteria of the International Classification of Diseases, Tenth Revision (ICD-10). The intensity of clinical manifestations was assessed using the Positive and Negative Syndrome Scale (PANSS), the Abnormal Involuntary Movement Scale (AIMS), and the Barnes Akathisia Rating Scale (BARS). Compliance was assessed using the Method for Measuring Medication Adherence in Psychiatry. Detailed differential diagnosis of tardive dyskinesia and tardive dystonia with akathisia and Huntington’s disease was presented. Substantiated treatment strategy and positive clinical dynamics with increased compliance were described.https://bulletin.ssmu.ru/jour/article/view/4598tardive dyskinesiatardive dystoniaschizophreniacomplianceakathisia |
| spellingShingle | E. G. Rahim E. G. Kornetova A. A. Goncharova A. N. Кornetov A. V. Semke The effect of antipsychotic-induced extrapyramidal disorders on patient’s compliance with schizophrenia (a clinical case) Бюллетень сибирской медицины tardive dyskinesia tardive dystonia schizophrenia compliance akathisia |
| title | The effect of antipsychotic-induced extrapyramidal disorders on patient’s compliance with schizophrenia (a clinical case) |
| title_full | The effect of antipsychotic-induced extrapyramidal disorders on patient’s compliance with schizophrenia (a clinical case) |
| title_fullStr | The effect of antipsychotic-induced extrapyramidal disorders on patient’s compliance with schizophrenia (a clinical case) |
| title_full_unstemmed | The effect of antipsychotic-induced extrapyramidal disorders on patient’s compliance with schizophrenia (a clinical case) |
| title_short | The effect of antipsychotic-induced extrapyramidal disorders on patient’s compliance with schizophrenia (a clinical case) |
| title_sort | effect of antipsychotic induced extrapyramidal disorders on patient s compliance with schizophrenia a clinical case |
| topic | tardive dyskinesia tardive dystonia schizophrenia compliance akathisia |
| url | https://bulletin.ssmu.ru/jour/article/view/4598 |
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