Navigating a stealthy invader: Insights from two different Streptococcus intermedius cases

Streptococcus intermedius, a gram-positive, beta-hemolytic, catalase-negative member of the Streptococcus milleri group, is a commensal organism within the human body that is known for its propensity to cause severe bacterial infections. This case report presents two distinct cases involving culture...

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Main Authors: Erica Casey Anders, Stanley Miller
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Journal of Family Medicine and Primary Care
Subjects:
Online Access:https://journals.lww.com/10.4103/jfmpc.jfmpc_723_24
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author Erica Casey Anders
Stanley Miller
author_facet Erica Casey Anders
Stanley Miller
author_sort Erica Casey Anders
collection DOAJ
description Streptococcus intermedius, a gram-positive, beta-hemolytic, catalase-negative member of the Streptococcus milleri group, is a commensal organism within the human body that is known for its propensity to cause severe bacterial infections. This case report presents two distinct cases involving culture-positive S. intermedius infections. The first case involves a 53-year-old man diagnosed with new liver, lung, and brain lesions in the setting of suspected renal cell carcinoma. In the second case, an 84-year-old woman was found to have S. intermedius bacteremia with concurrent culture-positive liver abscesses. These cases illustrate the intricate nature of S. intermedius infections, which may manifest with a diverse spectrum of clinically significant systemic symptoms. Presently, there are no standardized protocols for screening, and subsequently managing, S. intermedius infections. Since S. intermedius has the potential to mimic other infections or pathological conditions, it warrants space on a differential until a negative culture or PCR assay is obtained.
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institution Kabale University
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publisher Wolters Kluwer Medknow Publications
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spelling doaj-art-60fa4f344f83466aa4f470f5dc78142a2025-02-11T14:05:50ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632278-71352025-01-0114147047210.4103/jfmpc.jfmpc_723_24Navigating a stealthy invader: Insights from two different Streptococcus intermedius casesErica Casey AndersStanley MillerStreptococcus intermedius, a gram-positive, beta-hemolytic, catalase-negative member of the Streptococcus milleri group, is a commensal organism within the human body that is known for its propensity to cause severe bacterial infections. This case report presents two distinct cases involving culture-positive S. intermedius infections. The first case involves a 53-year-old man diagnosed with new liver, lung, and brain lesions in the setting of suspected renal cell carcinoma. In the second case, an 84-year-old woman was found to have S. intermedius bacteremia with concurrent culture-positive liver abscesses. These cases illustrate the intricate nature of S. intermedius infections, which may manifest with a diverse spectrum of clinically significant systemic symptoms. Presently, there are no standardized protocols for screening, and subsequently managing, S. intermedius infections. Since S. intermedius has the potential to mimic other infections or pathological conditions, it warrants space on a differential until a negative culture or PCR assay is obtained.https://journals.lww.com/10.4103/jfmpc.jfmpc_723_24bacteremialiver abscesspyogenic infectionsstreptococcus intermedius
spellingShingle Erica Casey Anders
Stanley Miller
Navigating a stealthy invader: Insights from two different Streptococcus intermedius cases
Journal of Family Medicine and Primary Care
bacteremia
liver abscess
pyogenic infections
streptococcus intermedius
title Navigating a stealthy invader: Insights from two different Streptococcus intermedius cases
title_full Navigating a stealthy invader: Insights from two different Streptococcus intermedius cases
title_fullStr Navigating a stealthy invader: Insights from two different Streptococcus intermedius cases
title_full_unstemmed Navigating a stealthy invader: Insights from two different Streptococcus intermedius cases
title_short Navigating a stealthy invader: Insights from two different Streptococcus intermedius cases
title_sort navigating a stealthy invader insights from two different streptococcus intermedius cases
topic bacteremia
liver abscess
pyogenic infections
streptococcus intermedius
url https://journals.lww.com/10.4103/jfmpc.jfmpc_723_24
work_keys_str_mv AT ericacaseyanders navigatingastealthyinvaderinsightsfromtwodifferentstreptococcusintermediuscases
AT stanleymiller navigatingastealthyinvaderinsightsfromtwodifferentstreptococcusintermediuscases