Isolated Rheumatoid Nodules: A Diagnostic Dilemma
We present a 27-year-old male with multiple nonpainful soft tissue masses over several metacarpals, bilateral elbows, the left wrist, and both knees since the age of 4. Physical exam was significant for firm, nonmobile, nodular growths over the extensor surfaces of bilateral elbows and knees and on...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/352352 |
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| author | Michael Gale Erin Gilbert David Blumenthal |
| author_facet | Michael Gale Erin Gilbert David Blumenthal |
| author_sort | Michael Gale |
| collection | DOAJ |
| description | We present a 27-year-old male with multiple nonpainful soft tissue masses over several metacarpals, bilateral elbows, the left wrist, and both knees since the age of 4. Physical exam was significant for firm, nonmobile, nodular growths over the extensor surfaces of bilateral elbows and knees and on the 2nd and 5th metacarpal phalangeal joints. Laboratory studies revealed an unremarkable rheumatoid factor, negative ANA screening and normal joint radiographs. Differential diagnosis included subcutaneous granuloma annulare (SGA), seronegative rheumatoid nodule, and calcinosis cutis. Biopsy is the only method to distinguish benign rheumatoid nodules from SGA. This case illustrates the importance of biopsy in diagnosis, an awareness of the potential complications, and the need for good follow-up. |
| format | Article |
| id | doaj-art-60f8a1b68f174e5ab11f5f35624439c2 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-60f8a1b68f174e5ab11f5f35624439c22025-08-20T03:34:57ZengWileyCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/352352352352Isolated Rheumatoid Nodules: A Diagnostic DilemmaMichael Gale0Erin Gilbert1David Blumenthal2Department of Medicine, Woodhull Medical Center, Brooklyn, NY 11206, USADepartment of Dermatology, Woodhull Medical Center, Brooklyn, NY 11206, USADepartment of Medicine, Woodhull Medical Center, Brooklyn, NY 11206, USAWe present a 27-year-old male with multiple nonpainful soft tissue masses over several metacarpals, bilateral elbows, the left wrist, and both knees since the age of 4. Physical exam was significant for firm, nonmobile, nodular growths over the extensor surfaces of bilateral elbows and knees and on the 2nd and 5th metacarpal phalangeal joints. Laboratory studies revealed an unremarkable rheumatoid factor, negative ANA screening and normal joint radiographs. Differential diagnosis included subcutaneous granuloma annulare (SGA), seronegative rheumatoid nodule, and calcinosis cutis. Biopsy is the only method to distinguish benign rheumatoid nodules from SGA. This case illustrates the importance of biopsy in diagnosis, an awareness of the potential complications, and the need for good follow-up.http://dx.doi.org/10.1155/2015/352352 |
| spellingShingle | Michael Gale Erin Gilbert David Blumenthal Isolated Rheumatoid Nodules: A Diagnostic Dilemma Case Reports in Medicine |
| title | Isolated Rheumatoid Nodules: A Diagnostic Dilemma |
| title_full | Isolated Rheumatoid Nodules: A Diagnostic Dilemma |
| title_fullStr | Isolated Rheumatoid Nodules: A Diagnostic Dilemma |
| title_full_unstemmed | Isolated Rheumatoid Nodules: A Diagnostic Dilemma |
| title_short | Isolated Rheumatoid Nodules: A Diagnostic Dilemma |
| title_sort | isolated rheumatoid nodules a diagnostic dilemma |
| url | http://dx.doi.org/10.1155/2015/352352 |
| work_keys_str_mv | AT michaelgale isolatedrheumatoidnodulesadiagnosticdilemma AT eringilbert isolatedrheumatoidnodulesadiagnosticdilemma AT davidblumenthal isolatedrheumatoidnodulesadiagnosticdilemma |