Retinoprotective effects of ascovertin under light influence in conditions of hyperglycemia
Experiments performed on white outbred 100 rats showed that light impact with the intensity of 6 000 lx y during 6 hours and radiation in the setting of alloxanic diabetes caused injury of most structural components of retina and significant microcirculatory disturbances in the sclera. Starting with...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2007-03-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/3216 |
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| author | S. V. Logvinov M. B. Plotnikov Ye. Yu. Varakuta A. A. Zhdankina A. V. Potapov Ye. P. Mikhulya |
| author_facet | S. V. Logvinov M. B. Plotnikov Ye. Yu. Varakuta A. A. Zhdankina A. V. Potapov Ye. P. Mikhulya |
| author_sort | S. V. Logvinov |
| collection | DOAJ |
| description | Experiments performed on white outbred 100 rats showed that light impact with the intensity of 6 000 lx y during 6 hours and radiation in the setting of alloxanic diabetes caused injury of most structural components of retina and significant microcirculatory disturbances in the sclera. Starting with 7 days after radiation, retina damages had focal character which was more evident during radiation in the setting of alloxanic diabetes. However, prolonged injection of ascovertin led to decreased decstruction and improved hemodynamics which was expressed in reliable decreasing focal area by 2.1 times after light impact and by 1.4 times after radiation in the setting of alloxanic diabetes. |
| format | Article |
| id | doaj-art-60f2ea71f0164c2fb38108d20a4ee4e9 |
| institution | Kabale University |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2007-03-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-60f2ea71f0164c2fb38108d20a4ee4e92025-08-20T03:37:16ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842007-03-0161394410.20538/1682-0363-2007-1-39-441872Retinoprotective effects of ascovertin under light influence in conditions of hyperglycemiaS. V. Logvinov0M. B. Plotnikov1Ye. Yu. Varakuta2A. A. Zhdankina3A. V. Potapov4Ye. P. Mikhulya5Сибирский государственный медицинский университетНИИ фармакологии ТНЦ СО РАМНСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетExperiments performed on white outbred 100 rats showed that light impact with the intensity of 6 000 lx y during 6 hours and radiation in the setting of alloxanic diabetes caused injury of most structural components of retina and significant microcirculatory disturbances in the sclera. Starting with 7 days after radiation, retina damages had focal character which was more evident during radiation in the setting of alloxanic diabetes. However, prolonged injection of ascovertin led to decreased decstruction and improved hemodynamics which was expressed in reliable decreasing focal area by 2.1 times after light impact and by 1.4 times after radiation in the setting of alloxanic diabetes.https://bulletin.ssmu.ru/jour/article/view/3216lightretinadiabetesascovertin |
| spellingShingle | S. V. Logvinov M. B. Plotnikov Ye. Yu. Varakuta A. A. Zhdankina A. V. Potapov Ye. P. Mikhulya Retinoprotective effects of ascovertin under light influence in conditions of hyperglycemia Бюллетень сибирской медицины light retina diabetes ascovertin |
| title | Retinoprotective effects of ascovertin under light influence in conditions of hyperglycemia |
| title_full | Retinoprotective effects of ascovertin under light influence in conditions of hyperglycemia |
| title_fullStr | Retinoprotective effects of ascovertin under light influence in conditions of hyperglycemia |
| title_full_unstemmed | Retinoprotective effects of ascovertin under light influence in conditions of hyperglycemia |
| title_short | Retinoprotective effects of ascovertin under light influence in conditions of hyperglycemia |
| title_sort | retinoprotective effects of ascovertin under light influence in conditions of hyperglycemia |
| topic | light retina diabetes ascovertin |
| url | https://bulletin.ssmu.ru/jour/article/view/3216 |
| work_keys_str_mv | AT svlogvinov retinoprotectiveeffectsofascovertinunderlightinfluenceinconditionsofhyperglycemia AT mbplotnikov retinoprotectiveeffectsofascovertinunderlightinfluenceinconditionsofhyperglycemia AT yeyuvarakuta retinoprotectiveeffectsofascovertinunderlightinfluenceinconditionsofhyperglycemia AT aazhdankina retinoprotectiveeffectsofascovertinunderlightinfluenceinconditionsofhyperglycemia AT avpotapov retinoprotectiveeffectsofascovertinunderlightinfluenceinconditionsofhyperglycemia AT yepmikhulya retinoprotectiveeffectsofascovertinunderlightinfluenceinconditionsofhyperglycemia |