The Impact of Mass Drug Administration on Lymphatic Filariasis
Mass drug administration (MDA) has made a significant impact on the control of lymphatic filariasis (LF) since the establishment of the Global Programme to Eliminate Lymphatic Filariasis. However, its implementation is associated with several challenges, hampering interruption of parasite transmissi...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2022/7504871 |
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| author | Isaac Frimpong Aboagye Yvonne Abena Afadua Addison |
| author_facet | Isaac Frimpong Aboagye Yvonne Abena Afadua Addison |
| author_sort | Isaac Frimpong Aboagye |
| collection | DOAJ |
| description | Mass drug administration (MDA) has made a significant impact on the control of lymphatic filariasis (LF) since the establishment of the Global Programme to Eliminate Lymphatic Filariasis. However, its implementation is associated with several challenges, hampering interruption of parasite transmission and LF elimination in endemic areas. This study assessed the impact of MDA by comparing baseline microfilaria and antigen prevalence with those after three years (mid-term) and ≥5 years of MDA implementation and their respective prevalence reductions and identified specific challenges that may hinder its effective implementation. Three years of MDA implementation were observed to have microfilaria prevalence reductions (88.54% to 98.66%) comparable to those of studies that implemented MDA for five to 10 years (≥5 years, 79.23% to 98.26%). Inadequate community understanding of and participation in the LF MDA programme are major drawbacks to its effective implementation. The implementation of MDA that incorporates community participation, incentivisation, education, and training strategies has the potential of increasing MDA coverage and compliance, thereby interrupting parasite transmission and reducing microfilarial prevalence to levels that warrant LF elimination. |
| format | Article |
| id | doaj-art-60f1da802616493f8ae3d273f8520bb2 |
| institution | Kabale University |
| issn | 1687-9694 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Tropical Medicine |
| spelling | doaj-art-60f1da802616493f8ae3d273f8520bb22025-08-20T03:34:56ZengWileyJournal of Tropical Medicine1687-96942022-01-01202210.1155/2022/7504871The Impact of Mass Drug Administration on Lymphatic FilariasisIsaac Frimpong Aboagye0Yvonne Abena Afadua Addison1Department of Animal Biology and Conservation ScienceDepartment of Animal Biology and Conservation ScienceMass drug administration (MDA) has made a significant impact on the control of lymphatic filariasis (LF) since the establishment of the Global Programme to Eliminate Lymphatic Filariasis. However, its implementation is associated with several challenges, hampering interruption of parasite transmission and LF elimination in endemic areas. This study assessed the impact of MDA by comparing baseline microfilaria and antigen prevalence with those after three years (mid-term) and ≥5 years of MDA implementation and their respective prevalence reductions and identified specific challenges that may hinder its effective implementation. Three years of MDA implementation were observed to have microfilaria prevalence reductions (88.54% to 98.66%) comparable to those of studies that implemented MDA for five to 10 years (≥5 years, 79.23% to 98.26%). Inadequate community understanding of and participation in the LF MDA programme are major drawbacks to its effective implementation. The implementation of MDA that incorporates community participation, incentivisation, education, and training strategies has the potential of increasing MDA coverage and compliance, thereby interrupting parasite transmission and reducing microfilarial prevalence to levels that warrant LF elimination.http://dx.doi.org/10.1155/2022/7504871 |
| spellingShingle | Isaac Frimpong Aboagye Yvonne Abena Afadua Addison The Impact of Mass Drug Administration on Lymphatic Filariasis Journal of Tropical Medicine |
| title | The Impact of Mass Drug Administration on Lymphatic Filariasis |
| title_full | The Impact of Mass Drug Administration on Lymphatic Filariasis |
| title_fullStr | The Impact of Mass Drug Administration on Lymphatic Filariasis |
| title_full_unstemmed | The Impact of Mass Drug Administration on Lymphatic Filariasis |
| title_short | The Impact of Mass Drug Administration on Lymphatic Filariasis |
| title_sort | impact of mass drug administration on lymphatic filariasis |
| url | http://dx.doi.org/10.1155/2022/7504871 |
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