Relation between grades of intervertebral disc degeneration and occupational activities of patients with lumbar disc herniation

Background/Aim. Intervertebral disc degeneration (IDD) occurs as consequence of combined effects of genetic, agerelated, environmental and occupational factors. Lumbar disc herniation (LDH) develops mostly due to IDD. The aim of this study was to investigate whether the frequency of LDH is higher at...

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Main Authors: Papić Monika, Papić Vladimir, Kresoja Milena, Munteanu Valerija, Mikov Ivan, Cigić Tomislav
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2017-01-01
Series:Vojnosanitetski Pregled
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Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600306P.pdf
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author Papić Monika
Papić Vladimir
Kresoja Milena
Munteanu Valerija
Mikov Ivan
Cigić Tomislav
author_facet Papić Monika
Papić Vladimir
Kresoja Milena
Munteanu Valerija
Mikov Ivan
Cigić Tomislav
author_sort Papić Monika
collection DOAJ
description Background/Aim. Intervertebral disc degeneration (IDD) occurs as consequence of combined effects of genetic, agerelated, environmental and occupational factors. Lumbar disc herniation (LDH) develops mostly due to IDD. The aim of this study was to investigate whether the frequency of LDH is higher at the level of the most pronounced IDD, and whether a category of physical workload influences higher IDD on level L3-L4, L4-L5 and L5-S1 separately. Methods. The research included 60 patients with permanent employment, hospitalized due to LDH. A grade of IDD was assessed by lumbosacral preoperative magnetic resonance imaging (MRI), according to Pfirmann's MRI classification system. Occupational factors were determined by a specific questionnaire. Results. Out of the 60 patients participating in the study, 33.3% had jobs with easy workload, 23% had moderate workload, while 43% had heavy workload. Herniated discs were found at level L3-L4 in 8.3%, at level L4-L5 in 46.7% and at level L5-S1 in 45% patients. The symptomatic discs at level L5-S1 showed statistically significant frequency of degenerative changes of grades IV and V. Binary logistic regression results showed that the strongest predictor of IDD grade for examined levels was physical workload. Positive association of physical workload and IDD grade was observed in all cases. Higher grades of IDD are more likely for patients with both higher TE and heavier physical workload (OR 2.011) at level L3-L4. At levels L4-L5 and L5-S1 higher degree of IDD was more likely for females with heavier physical workload (OR 1.978 and 2.433 respectively). Conclusion. Symptomatic discs show higher frequency of higher grades of IDD but herniation does not occur solely at the disc of the most prominent degenerative changes. The results suggest importance of inter- influence of physical workload and the years of employment and the inter-influence of physical workload and gender, on degeneration of lumbar discs.
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spelling doaj-art-60f047cd26544508a8a4ba54d958829f2025-08-20T03:34:56ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202017-01-0174121121112710.2298/VSP151112306P0042-84501600306PRelation between grades of intervertebral disc degeneration and occupational activities of patients with lumbar disc herniationPapić Monika0Papić Vladimir1Kresoja Milena2Munteanu Valerija3Mikov Ivan4Cigić Tomislav5Health Center Novi Sad, Department of Occupational Health, Novi SadClinical Center of Vojvodina, Clinic of Neurosurgery, Novi Sad + Faculty of Medicine, Novi SadFaculty of Sciences, Department of Mathematics and Informatics, Novi SadClinical Center of Vojvodina, Center of Radiology, Novi SadFaculty of Medicine, Novi Sad + Clinical Center of Vojvodina , Outpatient Department, Novi SadClinical Center of Vojvodina, Clinic of Neurosurgery, Novi Sad + Faculty of Medicine, Novi SadBackground/Aim. Intervertebral disc degeneration (IDD) occurs as consequence of combined effects of genetic, agerelated, environmental and occupational factors. Lumbar disc herniation (LDH) develops mostly due to IDD. The aim of this study was to investigate whether the frequency of LDH is higher at the level of the most pronounced IDD, and whether a category of physical workload influences higher IDD on level L3-L4, L4-L5 and L5-S1 separately. Methods. The research included 60 patients with permanent employment, hospitalized due to LDH. A grade of IDD was assessed by lumbosacral preoperative magnetic resonance imaging (MRI), according to Pfirmann's MRI classification system. Occupational factors were determined by a specific questionnaire. Results. Out of the 60 patients participating in the study, 33.3% had jobs with easy workload, 23% had moderate workload, while 43% had heavy workload. Herniated discs were found at level L3-L4 in 8.3%, at level L4-L5 in 46.7% and at level L5-S1 in 45% patients. The symptomatic discs at level L5-S1 showed statistically significant frequency of degenerative changes of grades IV and V. Binary logistic regression results showed that the strongest predictor of IDD grade for examined levels was physical workload. Positive association of physical workload and IDD grade was observed in all cases. Higher grades of IDD are more likely for patients with both higher TE and heavier physical workload (OR 2.011) at level L3-L4. At levels L4-L5 and L5-S1 higher degree of IDD was more likely for females with heavier physical workload (OR 1.978 and 2.433 respectively). Conclusion. Symptomatic discs show higher frequency of higher grades of IDD but herniation does not occur solely at the disc of the most prominent degenerative changes. The results suggest importance of inter- influence of physical workload and the years of employment and the inter-influence of physical workload and gender, on degeneration of lumbar discs.http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600306P.pdflumbosacral regioninervertebral disc degenerationoccupational exposureintervertebral disc displacement
spellingShingle Papić Monika
Papić Vladimir
Kresoja Milena
Munteanu Valerija
Mikov Ivan
Cigić Tomislav
Relation between grades of intervertebral disc degeneration and occupational activities of patients with lumbar disc herniation
Vojnosanitetski Pregled
lumbosacral region
inervertebral disc degeneration
occupational exposure
intervertebral disc displacement
title Relation between grades of intervertebral disc degeneration and occupational activities of patients with lumbar disc herniation
title_full Relation between grades of intervertebral disc degeneration and occupational activities of patients with lumbar disc herniation
title_fullStr Relation between grades of intervertebral disc degeneration and occupational activities of patients with lumbar disc herniation
title_full_unstemmed Relation between grades of intervertebral disc degeneration and occupational activities of patients with lumbar disc herniation
title_short Relation between grades of intervertebral disc degeneration and occupational activities of patients with lumbar disc herniation
title_sort relation between grades of intervertebral disc degeneration and occupational activities of patients with lumbar disc herniation
topic lumbosacral region
inervertebral disc degeneration
occupational exposure
intervertebral disc displacement
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600306P.pdf
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