Tuberous Sclerosis Complex Associated with Papillary Serous Carcinoma of the Peritoneum, Lymphangioleiomyomatosis, and Angiomyolipoma
Tuberous sclerosis complex (TSC) is associated with benign and malignant tumors, including lymphangioleiomyomatosis (LAM) and angiomyolipoma (AML). We herein describe the TSC case of a 50-year-old woman having a papillary serous carcinoma of the peritoneum (PSCP), LAM, and AML. On microscopic examin...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2011/564260 |
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| author | Tomihiro Wakamiya Yasuo Sugita Mariko Hashiguchi Tsuyoshi Iwasaka Osamu Tokunaga |
| author_facet | Tomihiro Wakamiya Yasuo Sugita Mariko Hashiguchi Tsuyoshi Iwasaka Osamu Tokunaga |
| author_sort | Tomihiro Wakamiya |
| collection | DOAJ |
| description | Tuberous sclerosis complex (TSC) is associated with benign and malignant tumors, including lymphangioleiomyomatosis (LAM) and angiomyolipoma (AML). We herein describe the TSC case of a 50-year-old woman having a papillary serous carcinoma of the peritoneum (PSCP), LAM, and AML. On microscopic examination, the PSCP cells showed a cuboidal to columnar shape, proliferated into the papillae, and infiltrated into the peritoneal cavity and anterior thoracic wall. On immunohistochemical evaluation, the tumor cells were positive for epithelial membrane antigen, human epidermal cytokeratins, and progesterone receptor, but negative for calretinin, carcinoembryonic antigen, MCF-7 cell line (Ber-EP4), and estrogen receptor. |
| format | Article |
| id | doaj-art-60e8f46f0dd74b2d8bc8fdeb63f8abd2 |
| institution | OA Journals |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-60e8f46f0dd74b2d8bc8fdeb63f8abd22025-08-20T02:35:18ZengWileyCase Reports in Pathology2090-67812090-679X2011-01-01201110.1155/2011/564260564260Tuberous Sclerosis Complex Associated with Papillary Serous Carcinoma of the Peritoneum, Lymphangioleiomyomatosis, and AngiomyolipomaTomihiro Wakamiya0Yasuo Sugita1Mariko Hashiguchi2Tsuyoshi Iwasaka3Osamu Tokunaga4Department of Pathology and Microbiology, Faculty of Medicine, Saga University, Saga City 849-8501, JapanDepartment of Pathology, School of Medicine, Kurume University, JapanDepartment of Obstetrics and Gynecology, Faculty of Medicine, Saga University, Saga City 849-8501, JapanDepartment of Obstetrics and Gynecology, Faculty of Medicine, Saga University, Saga City 849-8501, JapanDepartment of Pathology and Microbiology, Faculty of Medicine, Saga University, Saga City 849-8501, JapanTuberous sclerosis complex (TSC) is associated with benign and malignant tumors, including lymphangioleiomyomatosis (LAM) and angiomyolipoma (AML). We herein describe the TSC case of a 50-year-old woman having a papillary serous carcinoma of the peritoneum (PSCP), LAM, and AML. On microscopic examination, the PSCP cells showed a cuboidal to columnar shape, proliferated into the papillae, and infiltrated into the peritoneal cavity and anterior thoracic wall. On immunohistochemical evaluation, the tumor cells were positive for epithelial membrane antigen, human epidermal cytokeratins, and progesterone receptor, but negative for calretinin, carcinoembryonic antigen, MCF-7 cell line (Ber-EP4), and estrogen receptor.http://dx.doi.org/10.1155/2011/564260 |
| spellingShingle | Tomihiro Wakamiya Yasuo Sugita Mariko Hashiguchi Tsuyoshi Iwasaka Osamu Tokunaga Tuberous Sclerosis Complex Associated with Papillary Serous Carcinoma of the Peritoneum, Lymphangioleiomyomatosis, and Angiomyolipoma Case Reports in Pathology |
| title | Tuberous Sclerosis Complex Associated with Papillary Serous Carcinoma of the Peritoneum, Lymphangioleiomyomatosis, and Angiomyolipoma |
| title_full | Tuberous Sclerosis Complex Associated with Papillary Serous Carcinoma of the Peritoneum, Lymphangioleiomyomatosis, and Angiomyolipoma |
| title_fullStr | Tuberous Sclerosis Complex Associated with Papillary Serous Carcinoma of the Peritoneum, Lymphangioleiomyomatosis, and Angiomyolipoma |
| title_full_unstemmed | Tuberous Sclerosis Complex Associated with Papillary Serous Carcinoma of the Peritoneum, Lymphangioleiomyomatosis, and Angiomyolipoma |
| title_short | Tuberous Sclerosis Complex Associated with Papillary Serous Carcinoma of the Peritoneum, Lymphangioleiomyomatosis, and Angiomyolipoma |
| title_sort | tuberous sclerosis complex associated with papillary serous carcinoma of the peritoneum lymphangioleiomyomatosis and angiomyolipoma |
| url | http://dx.doi.org/10.1155/2011/564260 |
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