Melatonin Modulates ZAP70 and CD40 Transcripts via Histone Modifications in Canine Ileum Epithelial Cells

Melatonin Modulates ZAP70 and CD40 Transcripts via Histone Modifications in Canine Ileum Epithelial Cells

Melatonin (MLT), produced by the pineal gland and other tissues, is known for its anti-inflammatory effects, particularly in regulating inflammatory markers and cytokines in intestinal cells. Our study aimed to investigate how MLT influences the expression of inflammatory genes through histone modif...

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Bibliographic Details
Main Authors: Jian Hong, Saber Y. Adam, Shiqi Wang, Hao Huang, In Ho Kim, Abdelkareem A. Ahmed, Hao-Yu Liu, Demin Cai
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Veterinary Sciences
Subjects:
melatonin
transcriptome
ileum
canine
histone modifications
Online Access:https://www.mdpi.com/2306-7381/12/2/87
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