Effectiveness of a polycaprolactone scaffold combined with platelet-rich fibrin as guided tissue regeneration materials for preserving an implant-supported overdenture
Objectives: This study aimed to assess the effectiveness of ridge preservation using a polycaprolactone (PCL) scaffold combined with platelet-rich fibrin (PRF) to promote bone regeneration before implantation. Materials and Methods: This prospective study was conducted at Al-Azhar University in Egyp...
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| Format: | Article |
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Springer
2024-01-01
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| Series: | Saudi Dental Journal |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1013905223001621 |
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| author | Lobna Mohamed Abdel-Aziz Shahenda A. Abdallah Noura Mohammed bakr Sara M. Bahaa Ebtihal H. Zainalabdeen Monther Alsharif Shadia A. Elsayed |
| author_facet | Lobna Mohamed Abdel-Aziz Shahenda A. Abdallah Noura Mohammed bakr Sara M. Bahaa Ebtihal H. Zainalabdeen Monther Alsharif Shadia A. Elsayed |
| author_sort | Lobna Mohamed Abdel-Aziz |
| collection | DOAJ |
| description | Objectives: This study aimed to assess the effectiveness of ridge preservation using a polycaprolactone (PCL) scaffold combined with platelet-rich fibrin (PRF) to promote bone regeneration before implantation. Materials and Methods: This prospective study was conducted at Al-Azhar University in Egypt. It included 30 participants requiring the extraction of their last mandibular premolar before constructing an implant-supported overdenture. The participants were divided into three groups: Group A was treated with a PCL scaffold and PRF as ridge preservative materials, Group B was treated with PRF alone, and Group C (control) was treated with no preservative material. Bone samples were collected for histomorphometric analysis at implant placement. Results: The participants’ mean age was 65.3 ± 4.27 years, and 18 (60%) were male. Postoperative alveolar bone lengths differed significantly between Groups A and B (P = 0.001). However, alveolar bone width changes did not differ significantly among groups. In contrast, the postoperative bone density and loss differed significantly among groups (P = 0.001). Conclusion: Combining two ridge preservation techniques (PCL and PRF) enhanced participants’ alveolar bone remodelling by decreasing its resorption and maintaining its width. |
| format | Article |
| id | doaj-art-60db4316435444739fd2cf97fb0b5e7a |
| institution | OA Journals |
| issn | 1013-9052 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Springer |
| record_format | Article |
| series | Saudi Dental Journal |
| spelling | doaj-art-60db4316435444739fd2cf97fb0b5e7a2025-08-20T01:57:24ZengSpringerSaudi Dental Journal1013-90522024-01-0136115115710.1016/j.sdentj.2023.08.012Effectiveness of a polycaprolactone scaffold combined with platelet-rich fibrin as guided tissue regeneration materials for preserving an implant-supported overdentureLobna Mohamed Abdel-Aziz0Shahenda A. Abdallah1Noura Mohammed bakr2Sara M. Bahaa3Ebtihal H. Zainalabdeen4Monther Alsharif5Shadia A. Elsayed6Oral Medicine, Periodontology, Diagnosis and Oral Radiology, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, EgyptBiomaterial, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, EgyptOral and Dental Biology Department, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, EgyptRemovable Prosthodontic Department, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, EgyptDepartment of Oral Basic and Clinical Sciences, College of Dentistry, Taibah University, Al Madinah Al Munawwarah, Saudi ArabiaFaculty of Dentistry, University of Benghazi, Benghazi, LibyaOral Medicine, Periodontology, Diagnosis and Oral Radiology, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, Egypt; Department of Oral & Maxillofacial Surgery, College of Dentistry, Taibah University, Al Madinah Al Munawwarah, Saudi Arabia; Corresponding author at: Department of Oral and Maxillofacial Surgery, College of Dentistry, Taibah University, 344, Almadinah Almunawwarrah, Saudi Arabia, Faculty of Dental Medicine for Girls, Al-Azhar University.Objectives: This study aimed to assess the effectiveness of ridge preservation using a polycaprolactone (PCL) scaffold combined with platelet-rich fibrin (PRF) to promote bone regeneration before implantation. Materials and Methods: This prospective study was conducted at Al-Azhar University in Egypt. It included 30 participants requiring the extraction of their last mandibular premolar before constructing an implant-supported overdenture. The participants were divided into three groups: Group A was treated with a PCL scaffold and PRF as ridge preservative materials, Group B was treated with PRF alone, and Group C (control) was treated with no preservative material. Bone samples were collected for histomorphometric analysis at implant placement. Results: The participants’ mean age was 65.3 ± 4.27 years, and 18 (60%) were male. Postoperative alveolar bone lengths differed significantly between Groups A and B (P = 0.001). However, alveolar bone width changes did not differ significantly among groups. In contrast, the postoperative bone density and loss differed significantly among groups (P = 0.001). Conclusion: Combining two ridge preservation techniques (PCL and PRF) enhanced participants’ alveolar bone remodelling by decreasing its resorption and maintaining its width.http://www.sciencedirect.com/science/article/pii/S1013905223001621SocketImplantPolycaprolactonePlatelet-rich fibrin |
| spellingShingle | Lobna Mohamed Abdel-Aziz Shahenda A. Abdallah Noura Mohammed bakr Sara M. Bahaa Ebtihal H. Zainalabdeen Monther Alsharif Shadia A. Elsayed Effectiveness of a polycaprolactone scaffold combined with platelet-rich fibrin as guided tissue regeneration materials for preserving an implant-supported overdenture Saudi Dental Journal Socket Implant Polycaprolactone Platelet-rich fibrin |
| title | Effectiveness of a polycaprolactone scaffold combined with platelet-rich fibrin as guided tissue regeneration materials for preserving an implant-supported overdenture |
| title_full | Effectiveness of a polycaprolactone scaffold combined with platelet-rich fibrin as guided tissue regeneration materials for preserving an implant-supported overdenture |
| title_fullStr | Effectiveness of a polycaprolactone scaffold combined with platelet-rich fibrin as guided tissue regeneration materials for preserving an implant-supported overdenture |
| title_full_unstemmed | Effectiveness of a polycaprolactone scaffold combined with platelet-rich fibrin as guided tissue regeneration materials for preserving an implant-supported overdenture |
| title_short | Effectiveness of a polycaprolactone scaffold combined with platelet-rich fibrin as guided tissue regeneration materials for preserving an implant-supported overdenture |
| title_sort | effectiveness of a polycaprolactone scaffold combined with platelet rich fibrin as guided tissue regeneration materials for preserving an implant supported overdenture |
| topic | Socket Implant Polycaprolactone Platelet-rich fibrin |
| url | http://www.sciencedirect.com/science/article/pii/S1013905223001621 |
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