Oral Contraceptives after Myomectomy: A Short Term Trial
Following myomectomy the rate of fertility is restored and pregnancy may be attempted with a good outcome. In the present study a 3 month treatment with OCs in a group of women after a myomectomy was evaluated. The drug compliance and side effects, the benefits of OC in order to reduce symptoms, to...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2009/476897 |
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| author | Stefano Luisi Valentina Ciani Massimo Gabbanini Sofia Sollazzi Michela Torricelli Francesco Calonaci Felice Petraglia |
| author_facet | Stefano Luisi Valentina Ciani Massimo Gabbanini Sofia Sollazzi Michela Torricelli Francesco Calonaci Felice Petraglia |
| author_sort | Stefano Luisi |
| collection | DOAJ |
| description | Following myomectomy the rate of fertility is restored and
pregnancy may be attempted with a good outcome. In the present
study a 3 month treatment with OCs in a group of women after a
myomectomy was evaluated. The drug compliance and side effects,
the benefits of OC in order to reduce symptoms, to increase
post-surgical hemoglobin levels and to avoid an early pregnancy
after myomectomy were analyzed. A group of women (𝑛=55) each with myoma ≥5 cm was recruited: they presented menorrhagia,
pelvic pain, dyspareunia and dysmenorrhae. After laparotomic
myomectomy the women were divided into 3 groups. Group 1: women
(𝑛=16) treated with pill A (15 mcg of
ethynilestradiol + 60 mcg of gestodene); group 2: women
(𝑛=23) treated with pill B (20 mcg of
ethynilestradiol + 100 mcg of levonorgestrel); group 3:
women (𝑛=16) treated with a placebo (oral calcium). After three
months from myomectomy and treatment patients in each group
reported a reduced menorrhagia, dismenorrhea and pelvic pain.
Serum haemoglobin levels increased in all women (𝑃<.05). No pregnancy occurred in any group and the
compliance was good. A post surgery treatment by using oral
contraceptives guarentees pregnancy prevention, associated with
reduction of pain, and improvement of haematologic conditions. |
| format | Article |
| id | doaj-art-60d56911e4094976b71ed0a5f9c367c6 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-60d56911e4094976b71ed0a5f9c367c62025-08-20T03:34:57ZengWileyInternational Journal of Endocrinology1687-83371687-83452009-01-01200910.1155/2009/476897476897Oral Contraceptives after Myomectomy: A Short Term TrialStefano Luisi0Valentina Ciani1Massimo Gabbanini2Sofia Sollazzi3Michela Torricelli4Francesco Calonaci5Felice Petraglia6Obstetrics and Gynecology Unit, Department of Pediatrics, Gynecology, and Reproductive Medicine, University of Siena, 53100 Siena, ItalyObstetrics and Gynecology Unit, Department of Pediatrics, Gynecology, and Reproductive Medicine, University of Siena, 53100 Siena, ItalyObstetrics and Gynecology Unit, Department of Pediatrics, Gynecology, and Reproductive Medicine, University of Siena, 53100 Siena, ItalyObstetrics and Gynecology Unit, Department of Pediatrics, Gynecology, and Reproductive Medicine, University of Siena, 53100 Siena, ItalyObstetrics and Gynecology Unit, Department of Pediatrics, Gynecology, and Reproductive Medicine, University of Siena, 53100 Siena, ItalyObstetrics and Gynecology Unit, Department of Pediatrics, Gynecology, and Reproductive Medicine, University of Siena, 53100 Siena, ItalyObstetrics and Gynecology Unit, Department of Pediatrics, Gynecology, and Reproductive Medicine, University of Siena, 53100 Siena, ItalyFollowing myomectomy the rate of fertility is restored and pregnancy may be attempted with a good outcome. In the present study a 3 month treatment with OCs in a group of women after a myomectomy was evaluated. The drug compliance and side effects, the benefits of OC in order to reduce symptoms, to increase post-surgical hemoglobin levels and to avoid an early pregnancy after myomectomy were analyzed. A group of women (𝑛=55) each with myoma ≥5 cm was recruited: they presented menorrhagia, pelvic pain, dyspareunia and dysmenorrhae. After laparotomic myomectomy the women were divided into 3 groups. Group 1: women (𝑛=16) treated with pill A (15 mcg of ethynilestradiol + 60 mcg of gestodene); group 2: women (𝑛=23) treated with pill B (20 mcg of ethynilestradiol + 100 mcg of levonorgestrel); group 3: women (𝑛=16) treated with a placebo (oral calcium). After three months from myomectomy and treatment patients in each group reported a reduced menorrhagia, dismenorrhea and pelvic pain. Serum haemoglobin levels increased in all women (𝑃<.05). No pregnancy occurred in any group and the compliance was good. A post surgery treatment by using oral contraceptives guarentees pregnancy prevention, associated with reduction of pain, and improvement of haematologic conditions.http://dx.doi.org/10.1155/2009/476897 |
| spellingShingle | Stefano Luisi Valentina Ciani Massimo Gabbanini Sofia Sollazzi Michela Torricelli Francesco Calonaci Felice Petraglia Oral Contraceptives after Myomectomy: A Short Term Trial International Journal of Endocrinology |
| title | Oral Contraceptives after Myomectomy: A Short Term Trial |
| title_full | Oral Contraceptives after Myomectomy: A Short Term Trial |
| title_fullStr | Oral Contraceptives after Myomectomy: A Short Term Trial |
| title_full_unstemmed | Oral Contraceptives after Myomectomy: A Short Term Trial |
| title_short | Oral Contraceptives after Myomectomy: A Short Term Trial |
| title_sort | oral contraceptives after myomectomy a short term trial |
| url | http://dx.doi.org/10.1155/2009/476897 |
| work_keys_str_mv | AT stefanoluisi oralcontraceptivesaftermyomectomyashorttermtrial AT valentinaciani oralcontraceptivesaftermyomectomyashorttermtrial AT massimogabbanini oralcontraceptivesaftermyomectomyashorttermtrial AT sofiasollazzi oralcontraceptivesaftermyomectomyashorttermtrial AT michelatorricelli oralcontraceptivesaftermyomectomyashorttermtrial AT francescocalonaci oralcontraceptivesaftermyomectomyashorttermtrial AT felicepetraglia oralcontraceptivesaftermyomectomyashorttermtrial |