Staphylococcal scalded skin syndrome in neonate: Another face of CA-MRSA
Staphylococcal scalded skin syndrome (SSSS), also known as Ritter’s disease, in its severe form occurs predominantly in infants and children. It is caused by infection with group II (often phage group 71) Staphylococcus aureus. The foci of infection include nasopharynx, less commonly umbilicus, urin...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-01-01
|
| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_833_23 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849739403941904384 |
|---|---|
| author | M Mohamadiya Rizwana S Shanmugapriya M Jaya Sudha B Appalaraju S Ramesh |
| author_facet | M Mohamadiya Rizwana S Shanmugapriya M Jaya Sudha B Appalaraju S Ramesh |
| author_sort | M Mohamadiya Rizwana |
| collection | DOAJ |
| description | Staphylococcal scalded skin syndrome (SSSS), also known as Ritter’s disease, in its severe form occurs predominantly in infants and children. It is caused by infection with group II (often phage group 71) Staphylococcus aureus. The foci of infection include nasopharynx, less commonly umbilicus, urinary tract, superficial abrasion, conjunctivae, and blood. Staphylococci are non-motile, non-spore-forming, catalase-positive, gram-positive cocci that appear predominantly as grape-like clusters. Although this organism is frequently a part of normal human microbial flora, it can cause significant opportunistic infections under certain conditions such as when extremes of age groups are involved, the presence of indwelling medical devices, and intravenous (iv) drug abuse. Staphylococcus aureus may cause a variety of infectious manifestations ranging from relatively benign skin infections to life-threatening systemic illnesses. SSSS caused by S. aureus strains produces exfoliative toxins which result in the development of blisters, erythema, and desquamation. Here, we present a case of an 11-day-old neonate who was diagnosed with SSSS. The causative agent responsible for this syndrome was identified as methicillin-resistant Staphylococcus aureus (MRSA). The molecular characterization of the gene Panton-Valentine leukocidin (PVL) was done by polymerase chain reaction (PCR) and was detected positive for PVL which is a distinctive virulence factor seen almost in all of the community-acquired MRSA strains. The patient was discharged after parenteral clindamycin therapy with almost complete resolution of symptoms. |
| format | Article |
| id | doaj-art-60d24ba1c039460d8a53121cffbee86b |
| institution | DOAJ |
| issn | 0377-4929 0974-5130 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj-art-60d24ba1c039460d8a53121cffbee86b2025-08-20T03:06:17ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302025-01-0168122222710.4103/ijpm.ijpm_833_23Staphylococcal scalded skin syndrome in neonate: Another face of CA-MRSAM Mohamadiya RizwanaS ShanmugapriyaM Jaya SudhaB AppalarajuS RameshStaphylococcal scalded skin syndrome (SSSS), also known as Ritter’s disease, in its severe form occurs predominantly in infants and children. It is caused by infection with group II (often phage group 71) Staphylococcus aureus. The foci of infection include nasopharynx, less commonly umbilicus, urinary tract, superficial abrasion, conjunctivae, and blood. Staphylococci are non-motile, non-spore-forming, catalase-positive, gram-positive cocci that appear predominantly as grape-like clusters. Although this organism is frequently a part of normal human microbial flora, it can cause significant opportunistic infections under certain conditions such as when extremes of age groups are involved, the presence of indwelling medical devices, and intravenous (iv) drug abuse. Staphylococcus aureus may cause a variety of infectious manifestations ranging from relatively benign skin infections to life-threatening systemic illnesses. SSSS caused by S. aureus strains produces exfoliative toxins which result in the development of blisters, erythema, and desquamation. Here, we present a case of an 11-day-old neonate who was diagnosed with SSSS. The causative agent responsible for this syndrome was identified as methicillin-resistant Staphylococcus aureus (MRSA). The molecular characterization of the gene Panton-Valentine leukocidin (PVL) was done by polymerase chain reaction (PCR) and was detected positive for PVL which is a distinctive virulence factor seen almost in all of the community-acquired MRSA strains. The patient was discharged after parenteral clindamycin therapy with almost complete resolution of symptoms.https://journals.lww.com/10.4103/ijpm.ijpm_833_23bullaeerythemainfantskin lesionstoxin |
| spellingShingle | M Mohamadiya Rizwana S Shanmugapriya M Jaya Sudha B Appalaraju S Ramesh Staphylococcal scalded skin syndrome in neonate: Another face of CA-MRSA Indian Journal of Pathology and Microbiology bullae erythema infant skin lesions toxin |
| title | Staphylococcal scalded skin syndrome in neonate: Another face of CA-MRSA |
| title_full | Staphylococcal scalded skin syndrome in neonate: Another face of CA-MRSA |
| title_fullStr | Staphylococcal scalded skin syndrome in neonate: Another face of CA-MRSA |
| title_full_unstemmed | Staphylococcal scalded skin syndrome in neonate: Another face of CA-MRSA |
| title_short | Staphylococcal scalded skin syndrome in neonate: Another face of CA-MRSA |
| title_sort | staphylococcal scalded skin syndrome in neonate another face of ca mrsa |
| topic | bullae erythema infant skin lesions toxin |
| url | https://journals.lww.com/10.4103/ijpm.ijpm_833_23 |
| work_keys_str_mv | AT mmohamadiyarizwana staphylococcalscaldedskinsyndromeinneonateanotherfaceofcamrsa AT sshanmugapriya staphylococcalscaldedskinsyndromeinneonateanotherfaceofcamrsa AT mjayasudha staphylococcalscaldedskinsyndromeinneonateanotherfaceofcamrsa AT bappalaraju staphylococcalscaldedskinsyndromeinneonateanotherfaceofcamrsa AT sramesh staphylococcalscaldedskinsyndromeinneonateanotherfaceofcamrsa |