Aminoacyl‐tRNA synthetases in medicine and disease
Abstract Aminoacyl‐tRNA synthetases (ARSs) are essential and ubiquitous ‘house‐keeping’ enzymes responsible for charging amino acids to their cognate tRNAs and providing the substrates for global protein synthesis. Recent studies have revealed a role of multiple ARSs in pathology, and their potentia...
Saved in:
| Main Authors: | Peng Yao, Paul L. Fox |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2013-02-01
|
| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/emmm.201100626 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Human mitochondrial leucyl tRNA synthetase can suppress non cognate pathogenic mt‐tRNA mutations
by: Hue Tran Hornig‐Do, et al.
Published: (2014-01-01) -
Isoleucyl-tRNA synthetase 2 promotes pancreatic ductal adenocarcinoma proliferation and metastasis by stabilizing β-catenin
by: Yixun Jin, et al.
Published: (2025-05-01) -
Kinetic characterization of amino acid activation by aminoacyl‐tRNA synthetases using radiolabelled γ‐[32P]ATP
by: Igor Živković, et al.
Published: (2025-04-01) -
Potential Piperolactam A Isolated From Piper betle as Natural Inhibitors of Brucella Species Aminoacyl‐tRNA Synthetase for Livestock Infections: In Silico Approach
by: Diding Latipudin, et al.
Published: (2024-11-01) -
Atypical Presentation of IARS1‐Related Disorder: Expanding the Phenotype and Genotype
by: Parith Wongkittichote, et al.
Published: (2025-05-01)