Assessment of antibody levels in a population vaccinated with Sputnik V

Objectives — The objective of our study was to assess humoral response in a population of health workers after vaccination with the first and second doses of Sputnik V. Methods — SARS-CoV-2 total antibodies (IgG and IgM) were measured, using the Centaur XPT autoanalyzer, Siemens®, in 530 serum sampl...

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Main Authors: Diego Gonzalez, Federico Fortuna, Analy F. Fritzler, Juan J. Jamardo, Eliana Duarte, Carolina Ibar, Dario G. Jacobsen, Maria E. Estevez, J Aguirre, Belky B. Garzón, Ruben Absi, Esteban M. Repetto, Gelos Diego Sanchez, Damian Zopatti, Bibiana Fabre
Format: Article
Language:English
Published: Limited liability company «Science and Innovations» (Saratov) 2023-03-01
Series:Russian Open Medical Journal
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Online Access:https://romj.org/node/522
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author Diego Gonzalez
Federico Fortuna
Analy F. Fritzler
Juan J. Jamardo
Eliana Duarte
Carolina Ibar
Dario G. Jacobsen
Maria E. Estevez
J Aguirre
Belky B. Garzón
Ruben Absi
Esteban M. Repetto
Gelos Diego Sanchez
Damian Zopatti
Bibiana Fabre
author_facet Diego Gonzalez
Federico Fortuna
Analy F. Fritzler
Juan J. Jamardo
Eliana Duarte
Carolina Ibar
Dario G. Jacobsen
Maria E. Estevez
J Aguirre
Belky B. Garzón
Ruben Absi
Esteban M. Repetto
Gelos Diego Sanchez
Damian Zopatti
Bibiana Fabre
author_sort Diego Gonzalez
collection DOAJ
description Objectives — The objective of our study was to assess humoral response in a population of health workers after vaccination with the first and second doses of Sputnik V. Methods — SARS-CoV-2 total antibodies (IgG and IgM) were measured, using the Centaur XPT autoanalyzer, Siemens®, in 530 serum samples taken from health workers in Buenos Aires vaccinated with Sputnik V. Results — After 21 days of the first dose application, 10 individuals (1.9%) presented antibody levels <1.0 (non-reactive), while 520 subjects (98.1%) responded with antibody values >1.0 (reactive). The results, obtained 21 days after the second dose, show that only 2 individuals (0.38%) had antibody levels <1.0 (non-reactive) and 528 (99.6%) responded with antibody values >1.0 (reactive). Conclusion — This study results implied that two doses of Sputnik V vaccine generated a proper antibody response in virtually the entire studied population.
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issn 2304-3415
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publishDate 2023-03-01
publisher Limited liability company «Science and Innovations» (Saratov)
record_format Article
series Russian Open Medical Journal
spelling doaj-art-60bd8a53b4e348969d2728b4cbd6f4d72025-08-20T03:19:17ZengLimited liability company «Science and Innovations» (Saratov)Russian Open Medical Journal2304-34152023-03-01121e010210.15275/rusomj.2023.0102Assessment of antibody levels in a population vaccinated with Sputnik VDiego GonzalezFederico FortunaAnaly F. FritzlerJuan J. JamardoEliana DuarteCarolina IbarDario G. JacobsenMaria E. EstevezJ AguirreBelky B. GarzónRuben AbsiEsteban M. RepettoGelos Diego SanchezDamian ZopattiBibiana FabreObjectives — The objective of our study was to assess humoral response in a population of health workers after vaccination with the first and second doses of Sputnik V. Methods — SARS-CoV-2 total antibodies (IgG and IgM) were measured, using the Centaur XPT autoanalyzer, Siemens®, in 530 serum samples taken from health workers in Buenos Aires vaccinated with Sputnik V. Results — After 21 days of the first dose application, 10 individuals (1.9%) presented antibody levels <1.0 (non-reactive), while 520 subjects (98.1%) responded with antibody values >1.0 (reactive). The results, obtained 21 days after the second dose, show that only 2 individuals (0.38%) had antibody levels <1.0 (non-reactive) and 528 (99.6%) responded with antibody values >1.0 (reactive). Conclusion — This study results implied that two doses of Sputnik V vaccine generated a proper antibody response in virtually the entire studied population.https://romj.org/node/522covid-19sars-cov-2vaccinationsputnik vantibodies
spellingShingle Diego Gonzalez
Federico Fortuna
Analy F. Fritzler
Juan J. Jamardo
Eliana Duarte
Carolina Ibar
Dario G. Jacobsen
Maria E. Estevez
J Aguirre
Belky B. Garzón
Ruben Absi
Esteban M. Repetto
Gelos Diego Sanchez
Damian Zopatti
Bibiana Fabre
Assessment of antibody levels in a population vaccinated with Sputnik V
Russian Open Medical Journal
covid-19
sars-cov-2
vaccination
sputnik v
antibodies
title Assessment of antibody levels in a population vaccinated with Sputnik V
title_full Assessment of antibody levels in a population vaccinated with Sputnik V
title_fullStr Assessment of antibody levels in a population vaccinated with Sputnik V
title_full_unstemmed Assessment of antibody levels in a population vaccinated with Sputnik V
title_short Assessment of antibody levels in a population vaccinated with Sputnik V
title_sort assessment of antibody levels in a population vaccinated with sputnik v
topic covid-19
sars-cov-2
vaccination
sputnik v
antibodies
url https://romj.org/node/522
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