The relationship between acid-sensing ion channel, ASIC2, and oncogenic β-catenin signaling in ovarian cancer

Abstract Inflammation associated with incessant ovulation plays a key role in epithelial ovarian cancer (EOC) pathogenesis. Ion channels, such as acid-sensing ion channel-2 or ASIC2 are known to be upregulated in inflammatory conditions and may play a role in cancer cell invasion and metastasis. Pre...

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Bibliographic Details
Main Authors: Tanvi Joshi, Sagar Chokshi, Annelise Wilhite, Mary Howard Singleton, Elizabeth Catranis, Jennifer Scalici, Kevin J. Lee
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-03429-2
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