The Danger Model Approach to the Pathogenesis of the Rheumatic Diseases

The danger model was proposed by Polly Matzinger as complement to the traditional self-non-self- (SNS-) model to explain the immunoreactivity. The danger model proposes a central role of the tissular cells’ discomfort as an element to prime the immune response processes in opposition to the traditio...

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Bibliographic Details
Main Authors: César Pacheco-Tena, Susana Aideé González-Chávez
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2015/506089
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