Membrane lipid homeostasis dually regulates conformational transition of phosphoethanolamine transferase EptA
Abstract The phosphoethanolamine transferase EptA utilizes phosphatidylethanolamine (PE) in the bacterial cell membrane to modify the structure of lipopolysaccharide, thereby conferring antimicrobial resistance on Gram-negative pathogens. Previous studies have indicated that excessive consumption of...
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| Main Authors: | Zhenyu Ma, Sue C. Nang, Zhuo Liu, Jingyi Zhu, Kaijie Mu, Limei Xu, Min Xiao, Lushan Wang, Jian Li, Xukai Jiang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-54607-1 |
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