Ottawa nutritional guide intervention for nausea and vomiting in pregnancy: a randomized controlled trial protocol

Abstract Background Nausea and vomiting are frequent complaints during pregnancy, which can be accompanied by marital discord and sexual dissatisfaction, in addition to the hospitalization of pregnant women. Given the potential side effects of pharmaceutical treatments on both the mother and fetus,...

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Main Authors: Sana Nazmi, Fereshteh Behmanesh, Hossein-Ali Nikbakht, Seddigheh Esmaeilzadeh
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Reproductive Health
Subjects:
Online Access:https://doi.org/10.1186/s12978-025-02097-9
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author Sana Nazmi
Fereshteh Behmanesh
Hossein-Ali Nikbakht
Seddigheh Esmaeilzadeh
author_facet Sana Nazmi
Fereshteh Behmanesh
Hossein-Ali Nikbakht
Seddigheh Esmaeilzadeh
author_sort Sana Nazmi
collection DOAJ
description Abstract Background Nausea and vomiting are frequent complaints during pregnancy, which can be accompanied by marital discord and sexual dissatisfaction, in addition to the hospitalization of pregnant women. Given the potential side effects of pharmaceutical treatments on both the mother and fetus, many women prefer non-pharmacological interventions. This study will assess the impact of an educational program based on the Ottawa Nutritional Guide on symptoms in pregnant women and explore sexual satisfaction as a secondary outcome. Methods In this randomized controlled clinical trial, a total of 60 pregnant women aged between 15 and 45 years, who scored 3–16 on the Rhodes Index of Nausea, Vomiting and Retching (RINVR), will be selected via convenience sampling. They will be then divided into two intervention and control groups through block randomization. Data will be collected using a demographic and obstetric checklist, the RINVR, and the Hudson’s Index of Sexual Satisfaction (ISS). The intervention group will be received training on the Ottawa Nutritional Guide in two 60-min sessions, conducted in groups of two to five people. The control group, on the other hand, received routine care. The collected data will be analyzed using SPSS Version 22. Discussion Several studies have reported the effectiveness of the Ottawa Nutritional Guide in managing nausea and vomiting in pregnant women, as well as its positive impact on their quality of life and marital satisfaction. However, further research is required to validate these findings before considering it as a potential alternative to pharmaceutical methods during pregnancy. Trial registration This study was registered in the Iranian Registry of Clinical Trials (IRCT20180218038783N5, registered 03/09/2023).
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spelling doaj-art-608e7eec4dd247cc893c5d02f1231f472025-08-20T03:43:11ZengBMCReproductive Health1742-47552025-08-012211910.1186/s12978-025-02097-9Ottawa nutritional guide intervention for nausea and vomiting in pregnancy: a randomized controlled trial protocolSana Nazmi0Fereshteh Behmanesh1Hossein-Ali Nikbakht2Seddigheh Esmaeilzadeh3Student Research Committee, Babol University of Medical SciencesSocial Determinants of Health Research Center, Health Research Institute, Babol University of Medical SciencesSocial Determinants of Health Research Center, Health Research Institute, Babol University of Medical SciencesInfertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical SciencesAbstract Background Nausea and vomiting are frequent complaints during pregnancy, which can be accompanied by marital discord and sexual dissatisfaction, in addition to the hospitalization of pregnant women. Given the potential side effects of pharmaceutical treatments on both the mother and fetus, many women prefer non-pharmacological interventions. This study will assess the impact of an educational program based on the Ottawa Nutritional Guide on symptoms in pregnant women and explore sexual satisfaction as a secondary outcome. Methods In this randomized controlled clinical trial, a total of 60 pregnant women aged between 15 and 45 years, who scored 3–16 on the Rhodes Index of Nausea, Vomiting and Retching (RINVR), will be selected via convenience sampling. They will be then divided into two intervention and control groups through block randomization. Data will be collected using a demographic and obstetric checklist, the RINVR, and the Hudson’s Index of Sexual Satisfaction (ISS). The intervention group will be received training on the Ottawa Nutritional Guide in two 60-min sessions, conducted in groups of two to five people. The control group, on the other hand, received routine care. The collected data will be analyzed using SPSS Version 22. Discussion Several studies have reported the effectiveness of the Ottawa Nutritional Guide in managing nausea and vomiting in pregnant women, as well as its positive impact on their quality of life and marital satisfaction. However, further research is required to validate these findings before considering it as a potential alternative to pharmaceutical methods during pregnancy. Trial registration This study was registered in the Iranian Registry of Clinical Trials (IRCT20180218038783N5, registered 03/09/2023).https://doi.org/10.1186/s12978-025-02097-9Nausea and vomitingSexual satisfactionPregnancyWomen
spellingShingle Sana Nazmi
Fereshteh Behmanesh
Hossein-Ali Nikbakht
Seddigheh Esmaeilzadeh
Ottawa nutritional guide intervention for nausea and vomiting in pregnancy: a randomized controlled trial protocol
Reproductive Health
Nausea and vomiting
Sexual satisfaction
Pregnancy
Women
title Ottawa nutritional guide intervention for nausea and vomiting in pregnancy: a randomized controlled trial protocol
title_full Ottawa nutritional guide intervention for nausea and vomiting in pregnancy: a randomized controlled trial protocol
title_fullStr Ottawa nutritional guide intervention for nausea and vomiting in pregnancy: a randomized controlled trial protocol
title_full_unstemmed Ottawa nutritional guide intervention for nausea and vomiting in pregnancy: a randomized controlled trial protocol
title_short Ottawa nutritional guide intervention for nausea and vomiting in pregnancy: a randomized controlled trial protocol
title_sort ottawa nutritional guide intervention for nausea and vomiting in pregnancy a randomized controlled trial protocol
topic Nausea and vomiting
Sexual satisfaction
Pregnancy
Women
url https://doi.org/10.1186/s12978-025-02097-9
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