One-Step Fabrication of Microfluidic Channels in Polydimethylsiloxane: Influence of Laser Power on Channel Formation

Recent advancements in microfluidic technologies have revolutionized their applications, particularly in drug monitoring, continuous biochemical analysis, and real-time physiological assessments. However, the fabrication of microfluidic devices with precise flow control remains constrained by either...

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Main Authors: Seong-Yeop Kim, Han-Byeol Son, Hyo-Ryoung Lim
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/16/3/282
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author Seong-Yeop Kim
Han-Byeol Son
Hyo-Ryoung Lim
author_facet Seong-Yeop Kim
Han-Byeol Son
Hyo-Ryoung Lim
author_sort Seong-Yeop Kim
collection DOAJ
description Recent advancements in microfluidic technologies have revolutionized their applications, particularly in drug monitoring, continuous biochemical analysis, and real-time physiological assessments. However, the fabrication of microfluidic devices with precise flow control remains constrained by either cost-prohibitive photolithography processes or limited-precision 3D printing techniques. In this study, we propose a one-step fabrication method employing picosecond laser processing to directly create microfluidic channels in (PDMS). This method achieves micron-scale channel precision while significantly simplifying the fabrication process and reducing costs. This approach eliminates the need for additional encapsulation steps, further reducing contamination risks and improving production scalability. These findings highlight the potential of this fabrication method to advance next-generation wearable biochemical devices and personalized healthcare technologies.
format Article
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issn 2072-666X
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publishDate 2025-02-01
publisher MDPI AG
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series Micromachines
spelling doaj-art-60892abd527f491e862c59f125563be52025-08-20T02:42:22ZengMDPI AGMicromachines2072-666X2025-02-0116328210.3390/mi16030282One-Step Fabrication of Microfluidic Channels in Polydimethylsiloxane: Influence of Laser Power on Channel FormationSeong-Yeop Kim0Han-Byeol Son1Hyo-Ryoung Lim2Department of Chemical Engineering, College of Engineering, Pukyong National University, Busan 48513, Republic of KoreaMajor of Human Bioconvergence, Division of Smart Healthcare, College of Information Technology and Convergence, Pukyong National University, Busan 48513, Republic of KoreaMajor of Human Bioconvergence, Division of Smart Healthcare, College of Information Technology and Convergence, Pukyong National University, Busan 48513, Republic of KoreaRecent advancements in microfluidic technologies have revolutionized their applications, particularly in drug monitoring, continuous biochemical analysis, and real-time physiological assessments. However, the fabrication of microfluidic devices with precise flow control remains constrained by either cost-prohibitive photolithography processes or limited-precision 3D printing techniques. In this study, we propose a one-step fabrication method employing picosecond laser processing to directly create microfluidic channels in (PDMS). This method achieves micron-scale channel precision while significantly simplifying the fabrication process and reducing costs. This approach eliminates the need for additional encapsulation steps, further reducing contamination risks and improving production scalability. These findings highlight the potential of this fabrication method to advance next-generation wearable biochemical devices and personalized healthcare technologies.https://www.mdpi.com/2072-666X/16/3/282microfluidic channelspicosecond laser processingPDMS fabricationcapillary-driven fluid transportwearable biochemical devices
spellingShingle Seong-Yeop Kim
Han-Byeol Son
Hyo-Ryoung Lim
One-Step Fabrication of Microfluidic Channels in Polydimethylsiloxane: Influence of Laser Power on Channel Formation
Micromachines
microfluidic channels
picosecond laser processing
PDMS fabrication
capillary-driven fluid transport
wearable biochemical devices
title One-Step Fabrication of Microfluidic Channels in Polydimethylsiloxane: Influence of Laser Power on Channel Formation
title_full One-Step Fabrication of Microfluidic Channels in Polydimethylsiloxane: Influence of Laser Power on Channel Formation
title_fullStr One-Step Fabrication of Microfluidic Channels in Polydimethylsiloxane: Influence of Laser Power on Channel Formation
title_full_unstemmed One-Step Fabrication of Microfluidic Channels in Polydimethylsiloxane: Influence of Laser Power on Channel Formation
title_short One-Step Fabrication of Microfluidic Channels in Polydimethylsiloxane: Influence of Laser Power on Channel Formation
title_sort one step fabrication of microfluidic channels in polydimethylsiloxane influence of laser power on channel formation
topic microfluidic channels
picosecond laser processing
PDMS fabrication
capillary-driven fluid transport
wearable biochemical devices
url https://www.mdpi.com/2072-666X/16/3/282
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AT hyoryounglim onestepfabricationofmicrofluidicchannelsinpolydimethylsiloxaneinfluenceoflaserpoweronchannelformation