Importanţa modelelor animale în cercetarea oncologică: Un review / The importance of animal models in oncological research: A review
In oncology research, in vivo experiments on animal models have played and still play an essential role in understanding the etiology, evolution, diagnosis and therapy of human cancer. The purpose of this review is to highlight the importance of preclinical oncological studies on both experimental a...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Asociaţia Naţională a Fabricanţilor de Produse de Uz Veterinar
2020-12-01
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| Series: | Medicamentul Veterinar |
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| Online Access: | http://www.veterinarypharmacon.com/docs/2258-2020_VD_14(2).ART.3.RO.pdf |
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| _version_ | 1849416788753776640 |
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| author | Diana Mihaela Alexandru Ana-Maria Coman Răzvan Dobre Maria Crivineanu |
| author_facet | Diana Mihaela Alexandru Ana-Maria Coman Răzvan Dobre Maria Crivineanu |
| author_sort | Diana Mihaela Alexandru |
| collection | DOAJ |
| description | In oncology research, in vivo experiments on animal models have played and still play an essential role in understanding the etiology, evolution, diagnosis and therapy of human cancer. The purpose of this review is to highlight the importance of preclinical oncological studies on both experimental animals and pets that have developed spontaneous tumours, in the evolution of diagnostic methods and therapeutic
management of neoplastic diseases. Also, a series of criteria underlying the elaboration of an in vivo study are emphasized, regarding the species, breed, sex, age of the animals, the selected tumour line and its purpose, taking into account the obligation to respect the ethical principles regarding the use of
animals in research. |
| format | Article |
| id | doaj-art-607f0d993ba04840a677ef6f378aa0b4 |
| institution | Kabale University |
| issn | 1843-9527 2069-2463 |
| language | English |
| publishDate | 2020-12-01 |
| publisher | Asociaţia Naţională a Fabricanţilor de Produse de Uz Veterinar |
| record_format | Article |
| series | Medicamentul Veterinar |
| spelling | doaj-art-607f0d993ba04840a677ef6f378aa0b42025-08-20T03:33:03ZengAsociaţia Naţională a Fabricanţilor de Produse de Uz VeterinarMedicamentul Veterinar1843-95272069-24632020-12-011426067Importanţa modelelor animale în cercetarea oncologică: Un review / The importance of animal models in oncological research: A reviewDiana Mihaela Alexandru0Ana-Maria Coman1Răzvan Dobre2Maria Crivineanu3Facultatea de Medicină Veterinară, Bucureşti Institutul Oncologic „Prof. Dr. Alexandru Trestioreanu", BucureştiFacultatea de Medicină Veterinară, BucureştiFaculty of Veterinary Medicine, BucharestIn oncology research, in vivo experiments on animal models have played and still play an essential role in understanding the etiology, evolution, diagnosis and therapy of human cancer. The purpose of this review is to highlight the importance of preclinical oncological studies on both experimental animals and pets that have developed spontaneous tumours, in the evolution of diagnostic methods and therapeutic management of neoplastic diseases. Also, a series of criteria underlying the elaboration of an in vivo study are emphasized, regarding the species, breed, sex, age of the animals, the selected tumour line and its purpose, taking into account the obligation to respect the ethical principles regarding the use of animals in research.http://www.veterinarypharmacon.com/docs/2258-2020_VD_14(2).ART.3.RO.pdfcanceroncological researchexperimental oncologyanimal models |
| spellingShingle | Diana Mihaela Alexandru Ana-Maria Coman Răzvan Dobre Maria Crivineanu Importanţa modelelor animale în cercetarea oncologică: Un review / The importance of animal models in oncological research: A review Medicamentul Veterinar cancer oncological research experimental oncology animal models |
| title | Importanţa modelelor animale în cercetarea oncologică: Un review / The importance of animal models in oncological research: A review |
| title_full | Importanţa modelelor animale în cercetarea oncologică: Un review / The importance of animal models in oncological research: A review |
| title_fullStr | Importanţa modelelor animale în cercetarea oncologică: Un review / The importance of animal models in oncological research: A review |
| title_full_unstemmed | Importanţa modelelor animale în cercetarea oncologică: Un review / The importance of animal models in oncological research: A review |
| title_short | Importanţa modelelor animale în cercetarea oncologică: Un review / The importance of animal models in oncological research: A review |
| title_sort | importanta modelelor animale in cercetarea oncologica un review the importance of animal models in oncological research a review |
| topic | cancer oncological research experimental oncology animal models |
| url | http://www.veterinarypharmacon.com/docs/2258-2020_VD_14(2).ART.3.RO.pdf |
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