Establishment of a core outcome set for burn care research: development and international consensus
Objective To develop a core outcome set for international burn research.Design Development and international consensus, from April 2017 to November 2019.Methods Candidate outcomes were identified from systematic reviews and stakeholder interviews. Through a Delphi survey, international clinicians, r...
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BMJ Publishing Group
2022-12-01
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| Series: | BMJ Medicine |
| Online Access: | https://bmjmedicine.bmj.com/content/1/1/e000183.full |
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| author | Nukhba Zia Chris Metcalfe Jonathan Mathers Zephanie Tyack Anna Davies Sian Falder Baljit Dheansa Amber Young Sara Brookes Fiona Wood Jo Dumville Jamie Kirkham Tom Potokar Carmen Tsang Dale Edgar Nicole Gibran Jill Meirte Teruichi Harada Rajeev Ahuja Sarah Gaskell Sarah Smailes Marc Jeschke Murat Ali Cinar Amr Moghazy Jane Mary Blazeby |
| author_facet | Nukhba Zia Chris Metcalfe Jonathan Mathers Zephanie Tyack Anna Davies Sian Falder Baljit Dheansa Amber Young Sara Brookes Fiona Wood Jo Dumville Jamie Kirkham Tom Potokar Carmen Tsang Dale Edgar Nicole Gibran Jill Meirte Teruichi Harada Rajeev Ahuja Sarah Gaskell Sarah Smailes Marc Jeschke Murat Ali Cinar Amr Moghazy Jane Mary Blazeby |
| author_sort | Nukhba Zia |
| collection | DOAJ |
| description | Objective To develop a core outcome set for international burn research.Design Development and international consensus, from April 2017 to November 2019.Methods Candidate outcomes were identified from systematic reviews and stakeholder interviews. Through a Delphi survey, international clinicians, researchers, and UK patients prioritised outcomes. Anonymised feedback aimed to achieve consensus. Pre-defined criteria for retaining outcomes were agreed. A consensus meeting with voting was held to finalise the core outcome set.Results Data source examination identified 1021 unique outcomes grouped into 88 candidate outcomes. Stakeholders in round 1 of the survey, included 668 health professionals from 77 countries (18% from low or low middle income countries) and 126 UK patients or carers. After round 1, one outcome was discarded, and 13 new outcomes added. After round 2, 69 items were discarded, leaving 31 outcomes for the consensus meeting. Outcome merging and voting, in two rounds, with prespecified thresholds agreed seven core outcomes: death, specified complications, ability to do daily tasks, wound healing, neuropathic pain and itch, psychological wellbeing, and return to school or work.Conclusions This core outcome set caters for global burn research, and future trials are recommended to include measures of these outcomes. |
| format | Article |
| id | doaj-art-607e9cd973f44beb88cfedad54215db4 |
| institution | OA Journals |
| issn | 2754-0413 |
| language | English |
| publishDate | 2022-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Medicine |
| spelling | doaj-art-607e9cd973f44beb88cfedad54215db42025-08-20T01:48:05ZengBMJ Publishing GroupBMJ Medicine2754-04132022-12-011110.1136/bmjmed-2022-000183Establishment of a core outcome set for burn care research: development and international consensusNukhba Zia0Chris Metcalfe1Jonathan Mathers2Zephanie Tyack3Anna Davies4Sian Falder5Baljit Dheansa6Amber Young7Sara Brookes8Fiona Wood9Jo Dumville10Jamie Kirkham11Tom Potokar12Carmen Tsang13Dale Edgar14Nicole Gibran15Jill Meirte16Teruichi Harada17Rajeev Ahuja18Sarah Gaskell19Sarah Smailes20Marc Jeschke21Murat Ali Cinar22Amr Moghazy23Jane Mary Blazeby24Johns Hopkins International Injury Research Unit, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USABristol Trials Centre, University of Bristol, Bristol, UKInstitute of Applied Health Research, University of Birmingham, Birmingham, UKChild Health Research Centre, Faculty of Medicine, Centre for Children’s Burns and Trauma Research, Queensland University of Technology, Brisbane, QLD, Australia3 Centre for Academic Child Health, University of Bristol, Bristol, UKDepartment of plastic surgery, Alder Hey Children`s NHS Foundation Trust, Liverpool, UKDepartment of plastic surgery and burns, Queen Victoria Hospital, East Grinstead, UK1University of Michigan, Ann Arbor, United States of AmericaInstitute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UKBurn service, University of Western Australia, Perth, WA, AustraliaDivision of Population Health, Health Services Research & Primary Care, University of Manchester, Manchester, UKCentre for Biostatistics, The University of Manchester, Manchester, UKCentre for Global Burn Injury Policy and Research, Swansea University, Swansea, UKCentre for Surgical Research, Population Health Sciences, Bristol Biomedical Research Centre, Bristol Medical School, University of Bristol, Bristol, UKAdult Burns Unit, Fiona Stanley Hospital, Murdoch, WA, AustraliaUW Medicine Regional Burn Center, Harborview Medical Center, UW Department of Surgery, University of Washington (UW), Seattle, WA, USADepartment of Medicine and Health Sciences, University of Antwerp, Antwerpen, BelgiumSeitokai Medical and Social Welfare Corporation, Teramoto Memorial Hospital, Kawachinagano, Osaka, JapanDepartment of Burns & Plastic Surgery, Lok Nayak Hospital and Maulana Azad Medical College, New Delhi, IndiaPaediatric Psychosocial Service, Royal Manchester Children`s Hospital, Manchester, UKDepartment of physiontherapy, Broomfield Hospital, Mid Essex Hospitals, Chelmsford, UKDepartment of Surgery and Plastic Surgery, Sunnybrook Research Institute, University of Toronto, Toronto, ON, CanadaDepartment of Physical Therapy and Rehabilitation, Hasan Kalyoncu University, Gaziantep, TurkeyDepartment of plastic surgery, Suez Canal University, Ismailia, EgyptCentre for Surgical Research, Population Health Sciences, Bristol Biomedical Research Centre, Bristol Medical School, University of Bristol, Bristol, UKObjective To develop a core outcome set for international burn research.Design Development and international consensus, from April 2017 to November 2019.Methods Candidate outcomes were identified from systematic reviews and stakeholder interviews. Through a Delphi survey, international clinicians, researchers, and UK patients prioritised outcomes. Anonymised feedback aimed to achieve consensus. Pre-defined criteria for retaining outcomes were agreed. A consensus meeting with voting was held to finalise the core outcome set.Results Data source examination identified 1021 unique outcomes grouped into 88 candidate outcomes. Stakeholders in round 1 of the survey, included 668 health professionals from 77 countries (18% from low or low middle income countries) and 126 UK patients or carers. After round 1, one outcome was discarded, and 13 new outcomes added. After round 2, 69 items were discarded, leaving 31 outcomes for the consensus meeting. Outcome merging and voting, in two rounds, with prespecified thresholds agreed seven core outcomes: death, specified complications, ability to do daily tasks, wound healing, neuropathic pain and itch, psychological wellbeing, and return to school or work.Conclusions This core outcome set caters for global burn research, and future trials are recommended to include measures of these outcomes.https://bmjmedicine.bmj.com/content/1/1/e000183.full |
| spellingShingle | Nukhba Zia Chris Metcalfe Jonathan Mathers Zephanie Tyack Anna Davies Sian Falder Baljit Dheansa Amber Young Sara Brookes Fiona Wood Jo Dumville Jamie Kirkham Tom Potokar Carmen Tsang Dale Edgar Nicole Gibran Jill Meirte Teruichi Harada Rajeev Ahuja Sarah Gaskell Sarah Smailes Marc Jeschke Murat Ali Cinar Amr Moghazy Jane Mary Blazeby Establishment of a core outcome set for burn care research: development and international consensus BMJ Medicine |
| title | Establishment of a core outcome set for burn care research: development and international consensus |
| title_full | Establishment of a core outcome set for burn care research: development and international consensus |
| title_fullStr | Establishment of a core outcome set for burn care research: development and international consensus |
| title_full_unstemmed | Establishment of a core outcome set for burn care research: development and international consensus |
| title_short | Establishment of a core outcome set for burn care research: development and international consensus |
| title_sort | establishment of a core outcome set for burn care research development and international consensus |
| url | https://bmjmedicine.bmj.com/content/1/1/e000183.full |
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