Feasibility of Bariatric Surgery as a Strategy for Secondary Prevention in Cardiovascular Disease: A Report from the Swedish Obese Subjects Trial

Aims. Evaluation of bariatric surgery as secondary prevention in obese patients with ischemic heart disease (IHD). Methods. Analysis of data from 4047 subjects in the Swedish Obese Subjects (SOSs) study. Thirty-five patients with IHD are treated with bariatric surgery (𝑛=21) or conventional treatme...

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Main Authors: Lotta Delling, Kristjan Karason, Torsten Olbers, David Sjöström, Björn Wahlstrand, Björn Carlsson, Lena Carlsson, Kristina Narbro, Jan Karlsson, Carl Johan Behre, Lars Sjöström, Kaj Stenlöf
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Journal of Obesity
Online Access:http://dx.doi.org/10.1155/2010/102341
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author Lotta Delling
Kristjan Karason
Torsten Olbers
David Sjöström
Björn Wahlstrand
Björn Carlsson
Lena Carlsson
Kristina Narbro
Jan Karlsson
Carl Johan Behre
Lars Sjöström
Kaj Stenlöf
author_facet Lotta Delling
Kristjan Karason
Torsten Olbers
David Sjöström
Björn Wahlstrand
Björn Carlsson
Lena Carlsson
Kristina Narbro
Jan Karlsson
Carl Johan Behre
Lars Sjöström
Kaj Stenlöf
author_sort Lotta Delling
collection DOAJ
description Aims. Evaluation of bariatric surgery as secondary prevention in obese patients with ischemic heart disease (IHD). Methods. Analysis of data from 4047 subjects in the Swedish Obese Subjects (SOSs) study. Thirty-five patients with IHD are treated with bariatric surgery (𝑛=21) or conventional treatment (𝑛=14). Mean follow-up is 10.8 years. Results. Bariatric surgery resulted in sustained weight loss during the study period. After 2 years, the surgery group displayed significant reductions in cardiovascular risk factors, relief from cardiorespiratory symptoms, increments in physical activity, and improved quality of life. After 10 years, recovery from hypertension, diabetes, physical inactivity, and depression was still more common in the surgery group. There were no signs of increased cardiovascular morbidity or mortality in the surgery group. Conclusion. Bariatric surgery appears to be a safe and feasible treatment to achieve long-term weight loss and improvement in cardiovascular risk factors, symptoms, and quality of life in obese subjects with IHD.
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institution Kabale University
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publishDate 2010-01-01
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spelling doaj-art-60611b4e63fd4a3f8ec10b211ae5ba6e2025-02-03T01:09:32ZengWileyJournal of Obesity2090-07082090-07162010-01-01201010.1155/2010/102341102341Feasibility of Bariatric Surgery as a Strategy for Secondary Prevention in Cardiovascular Disease: A Report from the Swedish Obese Subjects TrialLotta Delling0Kristjan Karason1Torsten Olbers2David Sjöström3Björn Wahlstrand4Björn Carlsson5Lena Carlsson6Kristina Narbro7Jan Karlsson8Carl Johan Behre9Lars Sjöström10Kaj Stenlöf11Department of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gröna Stråket 8, 413 45 Göteborg, SwedenDepartment of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gröna Stråket 8, 413 45 Göteborg, SwedenDepartment of Surgery, The Sahlgrenska Academy, University of Gothenburg, SE-413 45 Göteborg, SwedenDepartment of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gröna Stråket 8, 413 45 Göteborg, SwedenDepartment of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gröna Stråket 8, 413 45 Göteborg, SwedenDepartment of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gröna Stråket 8, 413 45 Göteborg, SwedenDepartment of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gröna Stråket 8, 413 45 Göteborg, SwedenDepartment of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gröna Stråket 8, 413 45 Göteborg, SwedenDepartment of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gröna Stråket 8, 413 45 Göteborg, SwedenDepartment of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gröna Stråket 8, 413 45 Göteborg, SwedenDepartment of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gröna Stråket 8, 413 45 Göteborg, SwedenDepartment of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gröna Stråket 8, 413 45 Göteborg, SwedenAims. Evaluation of bariatric surgery as secondary prevention in obese patients with ischemic heart disease (IHD). Methods. Analysis of data from 4047 subjects in the Swedish Obese Subjects (SOSs) study. Thirty-five patients with IHD are treated with bariatric surgery (𝑛=21) or conventional treatment (𝑛=14). Mean follow-up is 10.8 years. Results. Bariatric surgery resulted in sustained weight loss during the study period. After 2 years, the surgery group displayed significant reductions in cardiovascular risk factors, relief from cardiorespiratory symptoms, increments in physical activity, and improved quality of life. After 10 years, recovery from hypertension, diabetes, physical inactivity, and depression was still more common in the surgery group. There were no signs of increased cardiovascular morbidity or mortality in the surgery group. Conclusion. Bariatric surgery appears to be a safe and feasible treatment to achieve long-term weight loss and improvement in cardiovascular risk factors, symptoms, and quality of life in obese subjects with IHD.http://dx.doi.org/10.1155/2010/102341
spellingShingle Lotta Delling
Kristjan Karason
Torsten Olbers
David Sjöström
Björn Wahlstrand
Björn Carlsson
Lena Carlsson
Kristina Narbro
Jan Karlsson
Carl Johan Behre
Lars Sjöström
Kaj Stenlöf
Feasibility of Bariatric Surgery as a Strategy for Secondary Prevention in Cardiovascular Disease: A Report from the Swedish Obese Subjects Trial
Journal of Obesity
title Feasibility of Bariatric Surgery as a Strategy for Secondary Prevention in Cardiovascular Disease: A Report from the Swedish Obese Subjects Trial
title_full Feasibility of Bariatric Surgery as a Strategy for Secondary Prevention in Cardiovascular Disease: A Report from the Swedish Obese Subjects Trial
title_fullStr Feasibility of Bariatric Surgery as a Strategy for Secondary Prevention in Cardiovascular Disease: A Report from the Swedish Obese Subjects Trial
title_full_unstemmed Feasibility of Bariatric Surgery as a Strategy for Secondary Prevention in Cardiovascular Disease: A Report from the Swedish Obese Subjects Trial
title_short Feasibility of Bariatric Surgery as a Strategy for Secondary Prevention in Cardiovascular Disease: A Report from the Swedish Obese Subjects Trial
title_sort feasibility of bariatric surgery as a strategy for secondary prevention in cardiovascular disease a report from the swedish obese subjects trial
url http://dx.doi.org/10.1155/2010/102341
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