An overview of the meningococcal disease and impact of the quadrivalent meningococcal conjugate vaccine

Meningitis is an inflammation of the meninges, which are the three membranes that cover the brain and the spinal cord; which occurs when the fluid surrounding the meninges becomes infected. Meningitis is a life-threatening disease, particularly in older people and immunocompromised cases. The est...

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Main Authors: Asmaa Alrobai, Jehan Alrahimi, Sahar El Hadad
Format: Article
Language:English
Published: ResearchersLinks, Ltd 2021-12-01
Series:Novel Research in Microbiology Journal
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Online Access:https://nrmj.journals.ekb.eg/article_208181_0ec3bc9542b93c446f2640089e0c26ca.pdf
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author Asmaa Alrobai
Jehan Alrahimi
Sahar El Hadad
author_facet Asmaa Alrobai
Jehan Alrahimi
Sahar El Hadad
author_sort Asmaa Alrobai
collection DOAJ
description Meningitis is an inflammation of the meninges, which are the three membranes that cover the brain and the spinal cord; which occurs when the fluid surrounding the meninges becomes infected. Meningitis is a life-threatening disease, particularly in older people and immunocompromised cases. The estimated annual numbers of meningitis cases in the industrialized countries are about 4-6 cases per 100,000 people. Meningococcal disease is caused by the bacterium Neisseria meningitides, which have A; C, Y, and W-135 serogroups. Immunization helps to protect the humans from infection, such as the meningococcal vaccine that protects from infection by A; C, Y, and W-135 serogroups. Meningococcal conjugate vaccines improve the immunogenicity potential, to prevent meningococcal disease. Several previous studies have documented the decrease in post-vaccination effectiveness induced by the meningococcal vaccines. However, effectiveness requires revaccination after a period of time from the first vaccination. The purposes of this article were to provide an overview of the meningitis disease, and demonstrate the effectiveness of the meningococcal conjugate vaccine.
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spelling doaj-art-605ef116cd0d48e29dfc11d00e0835c72025-08-20T03:34:48ZengResearchersLinks, LtdNovel Research in Microbiology Journal2537-02862537-02942021-12-01561463147910.21608/nrmj.2021.208181An overview of the meningococcal disease and impact of the quadrivalent meningococcal conjugate vaccineAsmaa Alrobai0Jehan Alrahimi1Sahar El Hadad2Department of Biological Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia Immunology Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi ArabiaResearch Center of Genetic Engineering and Bioinformatics, VACSERA, Cairo, EgyptMeningitis is an inflammation of the meninges, which are the three membranes that cover the brain and the spinal cord; which occurs when the fluid surrounding the meninges becomes infected. Meningitis is a life-threatening disease, particularly in older people and immunocompromised cases. The estimated annual numbers of meningitis cases in the industrialized countries are about 4-6 cases per 100,000 people. Meningococcal disease is caused by the bacterium Neisseria meningitides, which have A; C, Y, and W-135 serogroups. Immunization helps to protect the humans from infection, such as the meningococcal vaccine that protects from infection by A; C, Y, and W-135 serogroups. Meningococcal conjugate vaccines improve the immunogenicity potential, to prevent meningococcal disease. Several previous studies have documented the decrease in post-vaccination effectiveness induced by the meningococcal vaccines. However, effectiveness requires revaccination after a period of time from the first vaccination. The purposes of this article were to provide an overview of the meningitis disease, and demonstrate the effectiveness of the meningococcal conjugate vaccine.https://nrmj.journals.ekb.eg/article_208181_0ec3bc9542b93c446f2640089e0c26ca.pdfmeningococcalvaccinemeningitisneisseria meningitidesconjugate vaccine
spellingShingle Asmaa Alrobai
Jehan Alrahimi
Sahar El Hadad
An overview of the meningococcal disease and impact of the quadrivalent meningococcal conjugate vaccine
Novel Research in Microbiology Journal
meningococcal
vaccine
meningitis
neisseria meningitides
conjugate vaccine
title An overview of the meningococcal disease and impact of the quadrivalent meningococcal conjugate vaccine
title_full An overview of the meningococcal disease and impact of the quadrivalent meningococcal conjugate vaccine
title_fullStr An overview of the meningococcal disease and impact of the quadrivalent meningococcal conjugate vaccine
title_full_unstemmed An overview of the meningococcal disease and impact of the quadrivalent meningococcal conjugate vaccine
title_short An overview of the meningococcal disease and impact of the quadrivalent meningococcal conjugate vaccine
title_sort overview of the meningococcal disease and impact of the quadrivalent meningococcal conjugate vaccine
topic meningococcal
vaccine
meningitis
neisseria meningitides
conjugate vaccine
url https://nrmj.journals.ekb.eg/article_208181_0ec3bc9542b93c446f2640089e0c26ca.pdf
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