An overview of the meningococcal disease and impact of the quadrivalent meningococcal conjugate vaccine
Meningitis is an inflammation of the meninges, which are the three membranes that cover the brain and the spinal cord; which occurs when the fluid surrounding the meninges becomes infected. Meningitis is a life-threatening disease, particularly in older people and immunocompromised cases. The est...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
ResearchersLinks, Ltd
2021-12-01
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| Series: | Novel Research in Microbiology Journal |
| Subjects: | |
| Online Access: | https://nrmj.journals.ekb.eg/article_208181_0ec3bc9542b93c446f2640089e0c26ca.pdf |
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| Summary: | Meningitis is an inflammation of the meninges, which are the three membranes that cover
the brain and the spinal cord; which occurs when the fluid surrounding the meninges becomes
infected. Meningitis is a life-threatening disease, particularly in older people and
immunocompromised cases. The estimated annual numbers of meningitis cases in the
industrialized countries are about 4-6 cases per 100,000 people. Meningococcal disease is
caused by the bacterium Neisseria meningitides, which have A; C, Y, and W-135 serogroups.
Immunization helps to protect the humans from infection, such as the meningococcal vaccine
that protects from infection by A; C, Y, and W-135 serogroups. Meningococcal conjugate
vaccines improve the immunogenicity potential, to prevent meningococcal disease. Several
previous studies have documented the decrease in post-vaccination effectiveness induced by
the meningococcal vaccines. However, effectiveness requires revaccination after a period of
time from the first vaccination. The purposes of this article were to provide an overview of the
meningitis disease, and demonstrate the effectiveness of the meningococcal conjugate vaccine. |
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| ISSN: | 2537-0286 2537-0294 |