YAP/TAZ-mediated nuclear membrane rupture in promoting senescence of skeletal muscle associated with COPD

Abstract Patients with chronic obstructive pulmonary disease (COPD) often develop complications associated with sarcopenia; however, the underlying mechanisms remain unclear. Through a combination of in vitro and in vivo experiments, as well as bioinformatics analysis, our study identified YAP/TAZ a...

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Bibliographic Details
Main Authors: Ge Gong, Shuping Shen, Shaoran Shen, Ran Wang, Tianping Zheng, Wei Xu, Jianqing Wu
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Respiratory Research
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Online Access:https://doi.org/10.1186/s12931-025-03170-4
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