Germinal Center B Cells are Uniquely Targeted by Antibody-Suppressor CXCR5+CD8+ T Cells

Germinal Center B Cells are Uniquely Targeted by Antibody-Suppressor CXCR5+CD8+ T Cells

Background. Alloprimed antibody-suppressor CXCR5+CD8+ T cells (CD8+ TAb-supp cells) downregulate alloantibody production, mediate cytotoxicity of IgG+ B cells, and prolong allograft survival. The purpose of this investigation was to determine which immune-cell subsets are susceptible to CD8+ TAb-sup...

Full description

Saved in:

Bibliographic Details
Main Authors:	Jason M. Zimmerer, PhD, Sachi Chaudhari, BS, Kavya Koneru, BS, Jing L. Han, MD, PhD, Mahmoud Abdel-Rasoul, MA, Hope Uwase, MA, Tai Yi, MD, Christopher K. Breuer, MD, Ginny L. Bumgardner, MD, PhD
Format:	Article
Language:	English
Published:	Wolters Kluwer 2025-02-01
Series:	Transplantation Direct
Online Access:	http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001742
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Effect of Hematopoietic Stem Cell Transplantation Regimen on Tacrolimus Pharmacokinetics
by: Haruno Oku, BS, et al.
Published: (2025-01-01)

Graft-Versus-Host Disease Sustains Coagulation Activity for two Years After Pediatric Allogeneic Hematopoietic Stem Cell Transplantation
by: Satu Långström MD, PhD, et al.
Published: (2025-02-01)

Pembrolizumab and Pemetrexed for Older Patients With Nonsquamous NSCLC and Programmed Cell Death-Ligand 1 Tumor Proportion Scores of Less Than 50%
by: Yoshihito Kogure, MD, PhD, et al.
Published: (2025-03-01)

The Development and Applications of a Dual Optical Imaging System for Studying Glioma Stem Cells
by: Po-An Tai MD, PhD, et al.
Published: (2019-09-01)

Solid Predominant Histology and High Podoplanin Expression in Cancer-Associated Fibroblast Predict Primary Resistance to Osimertinib in EGFR-Mutated Lung Adenocarcinoma
by: Yuji Uehara, MD, et al.
Published: (2025-03-01)

Clinical Significance of Perioperative Minimal Residual Disease Detected by Circulating Tumor DNA in Patients With Lung Cancer With a Long Follow-up Data: An Exploratory Study
by: Shuta Ohara, MD, PhD, et al.
Published: (2025-03-01)

Single-cell immunopathology of recurrent acute generalized exanthematous pustulosis associated with vancomycin
by: Eric M. Mukherjee, MD, PhD, et al.
Published: (2025-05-01)

A Phase I/II Study of Ultra-Hypofractionated Carbon-ion Radiation therapy for Low- and Intermediate-Risk Localized Prostate Cancer
by: Noriyuki Okonogi, MD, PhD, et al.
Published: (2025-03-01)

Placental Vascular Malperfusion in Pregnancies With Congenital Heart Disease
by: Nour Rahnama, MD, et al.
Published: (2025-03-01)

EGFR-Mutated Lung Adenocarcinoma With Li–Fraumeni Syndrome: The Imperative for Germline Testing in Patients With a Family History, a Case Report
by: Hiroyuki Fujii, MD, et al.
Published: (2025-02-01)

Evolution of Treatment Outcomes and Prognostic Factors in Esophageal Cancer Surgery: A Retrospective Analysis of 1500 Consecutive Esophagostomies
by: Yasue Kimura, MD, PhD, et al.
Published: (2023-12-01)

Lumbosacral Plexopathy After Carbon-ion Radiation Therapy for Postoperative Pelvic Recurrence of Rectal Cancer: Subanalysis of a Prospective Observational Study (GUNMA 0801)
by: Takuya Kumazawa, MD, PhD, et al.
Published: (2025-03-01)

J-TAIL-2: A Prospective, Observational Study of Atezolizumab Combined With Carboplatin and Etoposide in Patients With Extensive-Stage SCLC in Japan
by: Eisaku Miyauchi, MD, PhD, et al.
Published: (2025-03-01)

Pilomatrixoma of the parotid region: A benign tumor mimicking metastatic cutaneous squamous cell carcinoma
by: Nikita Grieder, MD, et al.
Published: (2025-04-01)

Elevated mepolizumab levels in patients with severe asthma responsive to 1 year’s mepolizumab treatment
by: Takayasu Nishimaki, MD, et al.
Published: (2025-05-01)

Utility of Free Fibula Flap With an Extended Banana-shaped Skin Paddle for Oro-mandibular Reconstructions
by: Atsumori Hamahata, MD, PhD, et al.
Published: (2025-01-01)

Risk Factors and Management of Portal Vein Thrombosis after Hepatectomy: A Single-Center Experience
by: Kazuki Wakizaka, MD, PhD, et al.
Published: (2024-12-01)

Health Economic Evaluation of Patients With Colorectal Liver Metastases Randomized to ALPPS or TSH: Analysis From the LIGRO Trial
by: Kristina Hasselgren, MD, PhD, et al.
Published: (2024-03-01)

Effects of Minimally Invasive Versus Open Pancreatoduodenectomy on Short-Term Surgical Outcomes and Postoperative Nutritional and Immunological Statuses: A Single-Institution Propensity Score-Matched Study
by: Shinsei Yumoto, MD, et al.
Published: (2024-09-01)

Trans-arterial omental flap protection for infected femoral artery aneurysm in a patient with Parkes-Weber syndrome
by: Natsumi Iijima, MD, et al.
Published: (2025-02-01)

Diagnostic Accuracy of Lipase as Early Predictor of Postoperative Pancreatic Fistula: Results from the LIPADRAIN study
by: Béranger Doussot, MD, et al.
Published: (2024-09-01)

T cell immune senescence is associated with frailty and sarcopenia in lung transplant candidates
by: Joanna M. Schaenman, MD, PhD, et al.
Published: (2025-02-01)

Long-Term Follow-Up of Patients with Advanced Colorectal Liver Metastasis: A Survival Analysis from the Randomized Controlled Multicenter Trial LIGRO
by: Dennis Björk, MD, et al.
Published: (2024-09-01)

Local Recurrence of Rectal Cancer After Transanal Total Mesorectal Excision and Risk Factors: A Nationwide Multicenter Cohort Study in Japan
by: Takeru Matsuda, MD, PhD, et al.
Published: (2024-03-01)

Real-World Outcomes of Pralsetinib in RET Fusion-Positive NSCLC
by: Francesca Lucibello, MD, et al.
Published: (2025-01-01)

Alleviating effect of intranasal zinc on symptoms of allergic rhinitis
by: Huadong Xu, PhD, et al.
Published: (2025-05-01)

Comment on “Surgical Margin of Resected Colorectal Liver Metastases: How Accurate Is Surgeon Prediction?”
by: Yoichiro Uchida, MD, PhD, et al.
Published: (2024-09-01)

Comment on “Prognostic Effect of Liver Resection in Extended Cholecystectomy for T2 Gallbladder Cancer Revisited: A Retrospective Cohort Study with Propensity-Score-Matched Analysis”
by: Kojiro Taura, MD, PhD, et al.
Published: (2023-12-01)

Neoadjuvant Chemoradiotherapy Upregulates the Immunogenicity of Cold to Hot Tumors in Esophageal Cancer Patients
by: Yushi Nagaki, MD, PhD, et al.
Published: (2024-03-01)

A Simplified Technique for All-Inside Tibial Socket Retrograde Drill Guiding Using a 2- to 3.5-mm Concentric Cannula Without the All-Inside Tibial Guide Ring
by: Yizhong Peng, M.D., Ph.D., et al.
Published: (2025-01-01)

Robotic Versus Laparoscopic Liver Resection: A Nationwide Propensity Score Matched Analysis
by: Gabriela Pilz da Cunha, MD, et al.
Published: (2024-12-01)

Cardiac calcified amorphous tumor as a potential cause of cerebral infarction: A clinical case report
by: Hyunjin Kim, MD, et al.
Published: (2025-03-01)

Questionnaire to Survey Cosmetic Outcomes in Laparoscopic Surgery for Colorectal Cancer
by: Masaaki Miyo, MD, PhD, et al.
Published: (2024-09-01)

Five-Year Follow-Up of a Slowly Resorbable Biosynthetic P4HB Mesh (Phasix) in VHWG Grade 3 Incisional Hernia Repair
by: L. M. Van den Dop, MD, et al.
Published: (2023-12-01)

Multidetector-row Computed Tomography Analysis of the Radial Midpalmar Flap: A Retrospective Anatomical Study
by: Tien Linh Nguyen Doan, MD, PhD, et al.
Published: (2025-01-01)

Could Infectious Agents Play a Role in the Onset of Age-related Macular Degeneration? A Scoping Review
by: Petra P. Larsen, MD, PhD, et al.
Published: (2025-03-01)

Response to Comment on: “Prognostic Relevance of Primary Tumor Sidedness in Early-Stage Colorectal Cancer: An Integrated Analysis of 4 Randomized Controlled Trials (JCOG2003A)”
by: Akira Ouchi, MD, PhD, et al.
Published: (2024-12-01)

Dosimetric Comparison of Noncoplanar VMAT Without Rotating the Patient Couch Versus Conventional Coplanar/Noncoplanar VMAT for Head and Neck Cancer: First Report of Dynamic Swing Arc
by: Kouta Hirotaki, MS, et al.
Published: (2025-03-01)

Comment on “How Does Omitting Additional Surgery After Local Excision Affect the Prognostic Outcome of Patients With High-Risk T1 Colorectal Cancer?”
by: Stanislas Chaussade, MD, PhD, et al.
Published: (2024-06-01)

Efficacy and Safety of Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting Transforming Growth Factor-β and Programmed Death-Ligand 1, Plus Chemotherapy in Patients With Stage IV NSCLC
by: Christian Rolfo, MD, PhD, et al.
Published: (2025-01-01)