Maternal and Perinatal Outcomes of Early and Late Onset Preeclampsia with Severe Features in Secondary Health Care

Background: Preeclampsia is a condition characterized by new-onset hypertension during pregnancy, which can lead to various complications for both the mother and baby. It is categorized into early-onset preeclampsia (EO-PE) and late-onset preeclampsia (LO-PE) based on the timing of onset, each havin...

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Main Authors: Aryani Aziz, Uqbah Abdul Salam
Format: Article
Language:English
Published: Faculty of Medicine, Universitas Diponegoro 2025-01-01
Series:Jurnal Kedokteran Diponegoro
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Online Access:https://ejournal3.undip.ac.id/index.php/medico/article/view/46584
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author Aryani Aziz
Uqbah Abdul Salam
author_facet Aryani Aziz
Uqbah Abdul Salam
author_sort Aryani Aziz
collection DOAJ
description Background: Preeclampsia is a condition characterized by new-onset hypertension during pregnancy, which can lead to various complications for both the mother and baby. It is categorized into early-onset preeclampsia (EO-PE) and late-onset preeclampsia (LO-PE) based on the timing of onset, each having distinct pathophysiologies and complications. Objective: This study aims to evaluate maternal and perinatal outcomes in patients with early and late-onset severe preeclampsia. Methods: An analytic observational study with a cross-sectional design was conducted at a secondary healthcare facility. The study included 554 women with severe preeclampsia who delivered at the facility, categorized into EO-PE and LO-PE groups. Maternal characteristics and outcomes, as well as perinatal outcomes, were analyzed. Results: Out of the total cases, 40 (7.22%) were EO-PE and 514 (92.78%) were LO-PE. Maternal outcomes such as HELLP syndrome, visual impairment, placental abruption, oliguria, ICU admission, and eclampsia were significantly higher in the EO-PE group. Additionally, perinatal outcomes including birth weight and APGAR scores were notably worse in the EO-PE group. Conclusion: Adverse maternal and perinatal outcomes were significantly more prevalent in early-onset preeclampsia compared to late-onset preeclampsia.
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spelling doaj-art-6046a28b41b544c08fb3d3d2e27351ac2025-08-20T03:26:39ZengFaculty of Medicine, Universitas DiponegoroJurnal Kedokteran Diponegoro2540-88442025-01-0114161110.14710/dmj.v14i1.4658433011Maternal and Perinatal Outcomes of Early and Late Onset Preeclampsia with Severe Features in Secondary Health CareAryani Aziz0https://orcid.org/0009-0005-0634-9187Uqbah Abdul Salam1Faculty of medicine, Universitas Sriwijaya, Jl. Dokter Muhammad Ali, Sekip Jaya, Kemuning, Palembang, Indonesia 30114, IndonesiaFaculty of medicine Universitas Muhammadiyah Palembang, Indonesia, IndonesiaBackground: Preeclampsia is a condition characterized by new-onset hypertension during pregnancy, which can lead to various complications for both the mother and baby. It is categorized into early-onset preeclampsia (EO-PE) and late-onset preeclampsia (LO-PE) based on the timing of onset, each having distinct pathophysiologies and complications. Objective: This study aims to evaluate maternal and perinatal outcomes in patients with early and late-onset severe preeclampsia. Methods: An analytic observational study with a cross-sectional design was conducted at a secondary healthcare facility. The study included 554 women with severe preeclampsia who delivered at the facility, categorized into EO-PE and LO-PE groups. Maternal characteristics and outcomes, as well as perinatal outcomes, were analyzed. Results: Out of the total cases, 40 (7.22%) were EO-PE and 514 (92.78%) were LO-PE. Maternal outcomes such as HELLP syndrome, visual impairment, placental abruption, oliguria, ICU admission, and eclampsia were significantly higher in the EO-PE group. Additionally, perinatal outcomes including birth weight and APGAR scores were notably worse in the EO-PE group. Conclusion: Adverse maternal and perinatal outcomes were significantly more prevalent in early-onset preeclampsia compared to late-onset preeclampsia.https://ejournal3.undip.ac.id/index.php/medico/article/view/46584early-onset preeclampsialate-onset preeclampsiamaternal outcomesperinatal outcomes
spellingShingle Aryani Aziz
Uqbah Abdul Salam
Maternal and Perinatal Outcomes of Early and Late Onset Preeclampsia with Severe Features in Secondary Health Care
Jurnal Kedokteran Diponegoro
early-onset preeclampsia
late-onset preeclampsia
maternal outcomes
perinatal outcomes
title Maternal and Perinatal Outcomes of Early and Late Onset Preeclampsia with Severe Features in Secondary Health Care
title_full Maternal and Perinatal Outcomes of Early and Late Onset Preeclampsia with Severe Features in Secondary Health Care
title_fullStr Maternal and Perinatal Outcomes of Early and Late Onset Preeclampsia with Severe Features in Secondary Health Care
title_full_unstemmed Maternal and Perinatal Outcomes of Early and Late Onset Preeclampsia with Severe Features in Secondary Health Care
title_short Maternal and Perinatal Outcomes of Early and Late Onset Preeclampsia with Severe Features in Secondary Health Care
title_sort maternal and perinatal outcomes of early and late onset preeclampsia with severe features in secondary health care
topic early-onset preeclampsia
late-onset preeclampsia
maternal outcomes
perinatal outcomes
url https://ejournal3.undip.ac.id/index.php/medico/article/view/46584
work_keys_str_mv AT aryaniaziz maternalandperinataloutcomesofearlyandlateonsetpreeclampsiawithseverefeaturesinsecondaryhealthcare
AT uqbahabdulsalam maternalandperinataloutcomesofearlyandlateonsetpreeclampsiawithseverefeaturesinsecondaryhealthcare