Role of transmembrane protein 33 in tumorigenesis and development

Transmembrane protein 33 (TMEM33) is up-regulated in the majority of cancers. To change the expression of TMEM33 can significantly affect the proliferation, migration, and invasion of renal and cervical cancer cells. Its mechanisms of action may involve four aspects: 1)participation in lipid metabol...

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Bibliographic Details
Main Author: LOU Haijun, MENG Menggen, ZHANG Zhenyu, TONG Zhuoyun, WUDU Muli
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2025-02-01
Series:Jichu yixue yu linchuang
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Online Access:https://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2025-45-2-258.pdf
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Summary:Transmembrane protein 33 (TMEM33) is up-regulated in the majority of cancers. To change the expression of TMEM33 can significantly affect the proliferation, migration, and invasion of renal and cervical cancer cells. Its mechanisms of action may involve four aspects: 1)participation in lipid metabolism; 2)regulation of endoplasmic reticulum; 3)regulation of intracellular calcium homeostasis; 4) participation in angiogenesis.
ISSN:1001-6325