Fibromodulin-overexpressing fibroblast cells increase wound contraction, improve scar quality and enhance angiogenesis: an in-vivo study

Fibromodulin-overexpressing fibroblast cells increase wound contraction, improve scar quality and enhance angiogenesis: an in-vivo study

Abstract Introduction Fibromodulin, a small leucine rich proteoglycan has been suggested to have prominent role in wound healing. On the other hand, fibroblast cells, due to their ability to secrete growth factors and control inflammation in the wound area, have been proposed as effective approaches...

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Bibliographic Details
Main Authors: Negar Abdollahzadeh, Mehran Vatanchian, Fatemeh Oroojalian, Seyed Ehsan Enderami, Amir Amani, Reza Salarinia
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Biotechnology
Subjects:
Fibroblast
Cell isolation
Primary culture
Wound healing
Fibromodulin
Online Access:https://doi.org/10.1186/s12896-025-00975-5
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