Transcutaneous electrical acupoint stimulation for hypertension complicated by anxiety or sleep disorders: A pilot randomized controlled trial
Background: Hypertension is often accompanied by anxiety and sleep disorders, which further complicate the disease. This study aimed to evaluate the feasibility and effectiveness of transcutaneous electrical acupoint stimulation (TEAS) in patients with hypertension and anxiety or sleep disorders. Me...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-05-01
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| Series: | Complementary Therapies in Medicine |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0965229925000135 |
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| author | Xue-Ying Bao Cun-Zhi Liu Zi-Tong Qian Lu Wang Jian-Feng Tu Bin-Yan Li Xiao Wang Fang Wan Zhi-Han Li Zhao-Yi Liu Liang-Xiao Ma Li-Qiong Wang |
| author_facet | Xue-Ying Bao Cun-Zhi Liu Zi-Tong Qian Lu Wang Jian-Feng Tu Bin-Yan Li Xiao Wang Fang Wan Zhi-Han Li Zhao-Yi Liu Liang-Xiao Ma Li-Qiong Wang |
| author_sort | Xue-Ying Bao |
| collection | DOAJ |
| description | Background: Hypertension is often accompanied by anxiety and sleep disorders, which further complicate the disease. This study aimed to evaluate the feasibility and effectiveness of transcutaneous electrical acupoint stimulation (TEAS) in patients with hypertension and anxiety or sleep disorders. Methods: Eligible participants were randomly assigned to the 10 Hz TEAS, 2 Hz TEAS, or routine treatment groups in a 1:1:1 ratio. Participants continued their routine treatment during the trial, while those in the two TEAS groups received 12 sessions of 30-min TEAS treatment with different stimulation frequencies. The feasibility parameters were successful screening probability, enrollment rate, and dropout rate. The primary outcome was the change in office systolic blood pressure from baseline to week four. Secondary outcomes included changes in office diastolic blood pressure, heart rate, Pittsburgh Sleep Quality Index score, and Generalized Anxiety Disorder 7-item scale score from baseline to week four. Results: Eighty-eight participants (age 58.0 [51.0, 63.0] years; 49 women) were randomized. The successful screening probability was 56.1 %, the enrollment rate was 3.1 participants per week, and the dropout rate was 14.8 %. The change in office systolic blood pressure from baseline to week four was −2.8 ± 13.6 mm Hg, −6.4 ± 10.0 mm Hg, and −7.2 ± 11.2 mm Hg, respectively, in the 10 Hz TEAS, 2 Hz TEAS, and routine treatment groups (P = 0.332). No significant differences were noted, except for a change in the Pittsburgh Sleep Quality Index score (P = 0.014). Both 10 Hz (P = 0.024) and 2 Hz TEAS (P = 0.039) significantly improved sleep quality compared to routine treatment. Conclusions: In patients with hypertension having anxiety or sleep disorders, this study did not demonstrate the superiority of TEAS over routine treatment but did show an improvement in sleep quality and a downward trend in diastolic blood pressure. Therefore, a largescale trial is warranted. |
| format | Article |
| id | doaj-art-602906f5e91b4c079c456b3e67211a7d |
| institution | Kabale University |
| issn | 0965-2299 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Complementary Therapies in Medicine |
| spelling | doaj-art-602906f5e91b4c079c456b3e67211a7d2025-02-11T04:33:32ZengElsevierComplementary Therapies in Medicine0965-22992025-05-0189103138Transcutaneous electrical acupoint stimulation for hypertension complicated by anxiety or sleep disorders: A pilot randomized controlled trialXue-Ying Bao0Cun-Zhi Liu1Zi-Tong Qian2Lu Wang3Jian-Feng Tu4Bin-Yan Li5Xiao Wang6Fang Wan7Zhi-Han Li8Zhao-Yi Liu9Liang-Xiao Ma10Li-Qiong Wang11School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, China; International Acupuncture and Moxibustion Innovation Institute, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, China; International Acupuncture and Moxibustion Innovation Institute, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, China; International Acupuncture and Moxibustion Innovation Institute, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, China; Corresponding author.School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, China; International Acupuncture and Moxibustion Innovation Institute, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, China; Corresponding author at: School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, China.Background: Hypertension is often accompanied by anxiety and sleep disorders, which further complicate the disease. This study aimed to evaluate the feasibility and effectiveness of transcutaneous electrical acupoint stimulation (TEAS) in patients with hypertension and anxiety or sleep disorders. Methods: Eligible participants were randomly assigned to the 10 Hz TEAS, 2 Hz TEAS, or routine treatment groups in a 1:1:1 ratio. Participants continued their routine treatment during the trial, while those in the two TEAS groups received 12 sessions of 30-min TEAS treatment with different stimulation frequencies. The feasibility parameters were successful screening probability, enrollment rate, and dropout rate. The primary outcome was the change in office systolic blood pressure from baseline to week four. Secondary outcomes included changes in office diastolic blood pressure, heart rate, Pittsburgh Sleep Quality Index score, and Generalized Anxiety Disorder 7-item scale score from baseline to week four. Results: Eighty-eight participants (age 58.0 [51.0, 63.0] years; 49 women) were randomized. The successful screening probability was 56.1 %, the enrollment rate was 3.1 participants per week, and the dropout rate was 14.8 %. The change in office systolic blood pressure from baseline to week four was −2.8 ± 13.6 mm Hg, −6.4 ± 10.0 mm Hg, and −7.2 ± 11.2 mm Hg, respectively, in the 10 Hz TEAS, 2 Hz TEAS, and routine treatment groups (P = 0.332). No significant differences were noted, except for a change in the Pittsburgh Sleep Quality Index score (P = 0.014). Both 10 Hz (P = 0.024) and 2 Hz TEAS (P = 0.039) significantly improved sleep quality compared to routine treatment. Conclusions: In patients with hypertension having anxiety or sleep disorders, this study did not demonstrate the superiority of TEAS over routine treatment but did show an improvement in sleep quality and a downward trend in diastolic blood pressure. Therefore, a largescale trial is warranted.http://www.sciencedirect.com/science/article/pii/S0965229925000135AcupointTranscutaneous electrical acupoint stimulationComplementary therapyHypertensionSleep disorderAnxiety |
| spellingShingle | Xue-Ying Bao Cun-Zhi Liu Zi-Tong Qian Lu Wang Jian-Feng Tu Bin-Yan Li Xiao Wang Fang Wan Zhi-Han Li Zhao-Yi Liu Liang-Xiao Ma Li-Qiong Wang Transcutaneous electrical acupoint stimulation for hypertension complicated by anxiety or sleep disorders: A pilot randomized controlled trial Complementary Therapies in Medicine Acupoint Transcutaneous electrical acupoint stimulation Complementary therapy Hypertension Sleep disorder Anxiety |
| title | Transcutaneous electrical acupoint stimulation for hypertension complicated by anxiety or sleep disorders: A pilot randomized controlled trial |
| title_full | Transcutaneous electrical acupoint stimulation for hypertension complicated by anxiety or sleep disorders: A pilot randomized controlled trial |
| title_fullStr | Transcutaneous electrical acupoint stimulation for hypertension complicated by anxiety or sleep disorders: A pilot randomized controlled trial |
| title_full_unstemmed | Transcutaneous electrical acupoint stimulation for hypertension complicated by anxiety or sleep disorders: A pilot randomized controlled trial |
| title_short | Transcutaneous electrical acupoint stimulation for hypertension complicated by anxiety or sleep disorders: A pilot randomized controlled trial |
| title_sort | transcutaneous electrical acupoint stimulation for hypertension complicated by anxiety or sleep disorders a pilot randomized controlled trial |
| topic | Acupoint Transcutaneous electrical acupoint stimulation Complementary therapy Hypertension Sleep disorder Anxiety |
| url | http://www.sciencedirect.com/science/article/pii/S0965229925000135 |
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