HRMAS NMR Spectroscopy to Identify the Primary Metabolome of Bracigliano PGI Sweet Cherries and Correlate It with Nutraceutical and Quality Parameters

In 2023, the Italian Bracigliano sweet cherries were awarded the important European label PGI. However, reliable information on the compositional and nutraceutical quality of this product is still relatively undefined and fragmented. Therefore, we investigated fresh Bracigliano PGI cherries (Pallacc...

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Main Authors: Domenico Liguori, Pierluigi Mazzei
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Foods
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Online Access:https://www.mdpi.com/2304-8158/14/12/2120
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author Domenico Liguori
Pierluigi Mazzei
author_facet Domenico Liguori
Pierluigi Mazzei
author_sort Domenico Liguori
collection DOAJ
description In 2023, the Italian Bracigliano sweet cherries were awarded the important European label PGI. However, reliable information on the compositional and nutraceutical quality of this product is still relatively undefined and fragmented. Therefore, we investigated fresh Bracigliano PGI cherries (Pallaccia, Spernocchia, and Principe varieties) via HRMAS NMR spectroscopy in the semi-solid state, even though it represents an innovative and powerful technique that is still drastically unexplored. We demonstrated the HRMAS NMR suitability for this fruit type as well as identified the primary metabolome of studied Bracigliano PGI types. Moreover, chemometric techniques (ANOVA, PCA, and PLS-DA) permitted the significant definition of a variety-specific compositional fingerprint. HRMAS data were associated with the assessment of chemical and nutraceutical quality parameters. Importantly, in all studied varieties, a relatively high content of total phenols and antioxidant agents was detected, with Pallaccia cherries resulting as the healthiest ones. The heatmap clusterization revealed interesting correlations between HRMAS-NMR data and important quality parameters. Our results confirm the role of HRMAS in food chemistry and invite the creation of a spectral database of Bracigliano sweet cherries, useful to conduct traceability studies, protect consumers from frauds, and bolster the producers in promoting and certifying the quality of their products.
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spelling doaj-art-601dd2e54cf24cd49e6403e2425e5ede2025-08-20T03:26:52ZengMDPI AGFoods2304-81582025-06-011412212010.3390/foods14122120HRMAS NMR Spectroscopy to Identify the Primary Metabolome of Bracigliano PGI Sweet Cherries and Correlate It with Nutraceutical and Quality ParametersDomenico Liguori0Pierluigi Mazzei1Department of Pharmacy, University of Salerno, 84084 Fisciano, ItalyDepartment of Pharmacy, University of Salerno, 84084 Fisciano, ItalyIn 2023, the Italian Bracigliano sweet cherries were awarded the important European label PGI. However, reliable information on the compositional and nutraceutical quality of this product is still relatively undefined and fragmented. Therefore, we investigated fresh Bracigliano PGI cherries (Pallaccia, Spernocchia, and Principe varieties) via HRMAS NMR spectroscopy in the semi-solid state, even though it represents an innovative and powerful technique that is still drastically unexplored. We demonstrated the HRMAS NMR suitability for this fruit type as well as identified the primary metabolome of studied Bracigliano PGI types. Moreover, chemometric techniques (ANOVA, PCA, and PLS-DA) permitted the significant definition of a variety-specific compositional fingerprint. HRMAS data were associated with the assessment of chemical and nutraceutical quality parameters. Importantly, in all studied varieties, a relatively high content of total phenols and antioxidant agents was detected, with Pallaccia cherries resulting as the healthiest ones. The heatmap clusterization revealed interesting correlations between HRMAS-NMR data and important quality parameters. Our results confirm the role of HRMAS in food chemistry and invite the creation of a spectral database of Bracigliano sweet cherries, useful to conduct traceability studies, protect consumers from frauds, and bolster the producers in promoting and certifying the quality of their products.https://www.mdpi.com/2304-8158/14/12/2120metabolomicsnutraceuticalmolecular fingerprintmultivariate statistical analysesProtected Geographical Indication—PGIsemi-solid state NMR
spellingShingle Domenico Liguori
Pierluigi Mazzei
HRMAS NMR Spectroscopy to Identify the Primary Metabolome of Bracigliano PGI Sweet Cherries and Correlate It with Nutraceutical and Quality Parameters
Foods
metabolomics
nutraceutical
molecular fingerprint
multivariate statistical analyses
Protected Geographical Indication—PGI
semi-solid state NMR
title HRMAS NMR Spectroscopy to Identify the Primary Metabolome of Bracigliano PGI Sweet Cherries and Correlate It with Nutraceutical and Quality Parameters
title_full HRMAS NMR Spectroscopy to Identify the Primary Metabolome of Bracigliano PGI Sweet Cherries and Correlate It with Nutraceutical and Quality Parameters
title_fullStr HRMAS NMR Spectroscopy to Identify the Primary Metabolome of Bracigliano PGI Sweet Cherries and Correlate It with Nutraceutical and Quality Parameters
title_full_unstemmed HRMAS NMR Spectroscopy to Identify the Primary Metabolome of Bracigliano PGI Sweet Cherries and Correlate It with Nutraceutical and Quality Parameters
title_short HRMAS NMR Spectroscopy to Identify the Primary Metabolome of Bracigliano PGI Sweet Cherries and Correlate It with Nutraceutical and Quality Parameters
title_sort hrmas nmr spectroscopy to identify the primary metabolome of bracigliano pgi sweet cherries and correlate it with nutraceutical and quality parameters
topic metabolomics
nutraceutical
molecular fingerprint
multivariate statistical analyses
Protected Geographical Indication—PGI
semi-solid state NMR
url https://www.mdpi.com/2304-8158/14/12/2120
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