A fluorescent composite of europium metal organic framework with carbon dots for highly sensitive and specific detection of ciprofloxacin
The excessive and non-judicious use of antibiotics contributes to the majority of pharmaceutical contaminants, leading to negative influence on the environment and human health. Therefore, it is crucial to develop detection techniques for antibiotic contamination that can produce a rapid, sensitive,...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-12-01
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| Series: | Talanta Open |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S266683192500092X |
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| Summary: | The excessive and non-judicious use of antibiotics contributes to the majority of pharmaceutical contaminants, leading to negative influence on the environment and human health. Therefore, it is crucial to develop detection techniques for antibiotic contamination that can produce a rapid, sensitive, and antibiotic-selective response in diverse samples. In this study, a novel composite of europium-based MOFs and red emissive carbon dots (RCDs) was synthesized for sensitive and selective fluorometric sensing of ciprofloxacin (CIP). The RCDs@Eu-BTE composite was characterized using different microscopic and spectroscopic techniques. Notably, the composite demonstrated intense fluorescence emission as compared to Eu-BTE and RCDs alone. The enhanced fluorescence of RCDs@Eu-BTE composite resulted in greater sensitivity towards CIP with a limit of detection (LOD) of 0.13 µg/L over a wide linear detection range (0.1–100 µg/L). Moreover, the prepared RCDs@Eu-BTE composite exhibited good stability, easy regeneration, and efficient reusability, indicating its potential as an effective fluorescence probe for analytical applications. |
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| ISSN: | 2666-8319 |