Inhaling Poor Health: The Impact of Air Pollution on Cardiovascular Kidney Metabolic Syndrome
Air pollution, mostly from fossil fuel sources, is the leading environmental cause of global morbidity and mortality and is intricately linked to climate change. There is emerging evidence indicating that air pollution imposes most of its risk through proximate cardiovascular kidney and metabolic (C...
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Houston Methodist DeBakey Heart & Vascular Center
2024-11-01
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| Series: | Methodist DeBakey Cardiovascular Journal |
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| Online Access: | https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1487 |
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| author | Haitham Khraishah Sanjay Rajagopalan |
| author_facet | Haitham Khraishah Sanjay Rajagopalan |
| author_sort | Haitham Khraishah |
| collection | DOAJ |
| description | Air pollution, mostly from fossil fuel sources, is the leading environmental cause of global morbidity and mortality and is intricately linked to climate change. There is emerging evidence indicating that air pollution imposes most of its risk through proximate cardiovascular kidney and metabolic (CKM) etiologies. Indeed, there is compelling evidence linking air pollution to the genesis of insulin resistance, type 2 diabetes, hypertension, and other risk factors. Air pollution frequently coexists with factors such as noise, with levels and risks influenced substantially by additional factors such as social determinants and natural and built environment features. Persistent disparities regarding the impact and new sources of air pollution, such as wildfires attributable to climate change, have renewed the urgency to better understand root sources, characterize their health effects, and disseminate this information for personal protection and policy impacts. In this review, we summarize evidence associating air pollution with cardiovascular health, the impact of air pollution on CKM health, and how interactions with other exposures and personal characteristics may modify these associations. Finally, we discuss new integrated approaches to capture risk from air pollution in the context of an exposomic framework. |
| format | Article |
| id | doaj-art-60022b1193bb480f93027aae44eefc37 |
| institution | OA Journals |
| issn | 1947-6108 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Houston Methodist DeBakey Heart & Vascular Center |
| record_format | Article |
| series | Methodist DeBakey Cardiovascular Journal |
| spelling | doaj-art-60022b1193bb480f93027aae44eefc372025-08-20T02:33:23ZengHouston Methodist DeBakey Heart & Vascular CenterMethodist DeBakey Cardiovascular Journal1947-61082024-11-01205475810.14797/mdcvj.14871465Inhaling Poor Health: The Impact of Air Pollution on Cardiovascular Kidney Metabolic SyndromeHaitham Khraishah0https://orcid.org/0000-0003-0003-5089Sanjay Rajagopalan1https://orcid.org/0000-0001-6669-8163University Hospitals, Harrington Heart & Vascular Institute, Case Western Reserve University, Cleveland, OhioUniversity Hospitals, Harrington Heart & Vascular Institute, Case Western Reserve University, Cleveland, OhioAir pollution, mostly from fossil fuel sources, is the leading environmental cause of global morbidity and mortality and is intricately linked to climate change. There is emerging evidence indicating that air pollution imposes most of its risk through proximate cardiovascular kidney and metabolic (CKM) etiologies. Indeed, there is compelling evidence linking air pollution to the genesis of insulin resistance, type 2 diabetes, hypertension, and other risk factors. Air pollution frequently coexists with factors such as noise, with levels and risks influenced substantially by additional factors such as social determinants and natural and built environment features. Persistent disparities regarding the impact and new sources of air pollution, such as wildfires attributable to climate change, have renewed the urgency to better understand root sources, characterize their health effects, and disseminate this information for personal protection and policy impacts. In this review, we summarize evidence associating air pollution with cardiovascular health, the impact of air pollution on CKM health, and how interactions with other exposures and personal characteristics may modify these associations. Finally, we discuss new integrated approaches to capture risk from air pollution in the context of an exposomic framework.https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1487air pollutionenvironmentcardiovascularkidneymetabolic |
| spellingShingle | Haitham Khraishah Sanjay Rajagopalan Inhaling Poor Health: The Impact of Air Pollution on Cardiovascular Kidney Metabolic Syndrome Methodist DeBakey Cardiovascular Journal air pollution environment cardiovascular kidney metabolic |
| title | Inhaling Poor Health: The Impact of Air Pollution on Cardiovascular Kidney Metabolic Syndrome |
| title_full | Inhaling Poor Health: The Impact of Air Pollution on Cardiovascular Kidney Metabolic Syndrome |
| title_fullStr | Inhaling Poor Health: The Impact of Air Pollution on Cardiovascular Kidney Metabolic Syndrome |
| title_full_unstemmed | Inhaling Poor Health: The Impact of Air Pollution on Cardiovascular Kidney Metabolic Syndrome |
| title_short | Inhaling Poor Health: The Impact of Air Pollution on Cardiovascular Kidney Metabolic Syndrome |
| title_sort | inhaling poor health the impact of air pollution on cardiovascular kidney metabolic syndrome |
| topic | air pollution environment cardiovascular kidney metabolic |
| url | https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1487 |
| work_keys_str_mv | AT haithamkhraishah inhalingpoorhealththeimpactofairpollutiononcardiovascularkidneymetabolicsyndrome AT sanjayrajagopalan inhalingpoorhealththeimpactofairpollutiononcardiovascularkidneymetabolicsyndrome |