Protocol for a systematic review on tertiary prevention interventions for patients with stroke in African countries

Introduction Stroke is one of the common causes of mortality, morbidity and years of life lost worldwide. Baseline research on stroke epidemiology, prevention, acute and rehabilitative interventions in Africa is necessary to approach specific contexts and regional circumstances. Most studies on stro...

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Main Authors: Adamu Addissie, Eva Johanna Kantelhardt, Thomas Frese, Eric Sven Kroeber, Lucas Adam, Alexander Bauer, Susanne Unverzagt
Format: Article
Language:English
Published: BMJ Publishing Group 2020-09-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/9/e038459.full
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author Adamu Addissie
Eva Johanna Kantelhardt
Thomas Frese
Eric Sven Kroeber
Lucas Adam
Alexander Bauer
Susanne Unverzagt
author_facet Adamu Addissie
Eva Johanna Kantelhardt
Thomas Frese
Eric Sven Kroeber
Lucas Adam
Alexander Bauer
Susanne Unverzagt
author_sort Adamu Addissie
collection DOAJ
description Introduction Stroke is one of the common causes of mortality, morbidity and years of life lost worldwide. Baseline research on stroke epidemiology, prevention, acute and rehabilitative interventions in Africa is necessary to approach specific contexts and regional circumstances. Most studies on stroke have been conducted in high-income countries. This protocol describes the methodology to summarise the best available evidence on tertiary preventive strategies like rehabilitation interventions for patients with stroke in African contexts.Methods and analysis We will include experimental studies and prospective cohort studies conducted in African countries. A protocol has been registered in PROSPERO. Systematic search will include eight electronic databases (MEDLINE, Embase, the Cochrane Library, CINAHL, Cab-Direct, Physiotherapy Evidence Database (PEDro), African Journals Online and African Index Medicus) and the International Clinical Trials Register Platform and base on predefined search terms. We will search from inception of each database and repeat this strategy 3 months prior to review submission. Details of all eligible studies will be extracted and risk of bias for outcomes on global disability or dependence in daily living will be assessed. Main aim of this systematic review is to provide a narrative description of evidence on tertiary prevention strategies (including rehabilitation) for stroke. This description will be visualised in structured tables to aid interpretation of study characteristics, intervention effects and certainty of the evidence.Ethics and dissemination No ethical approval is necessary. Results will be presented in national and international conferences and published in a peer-reviewed journal.PROSPERO registration number CRD42020159125.
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spelling doaj-art-5ffbd782deb24b6eadac8cc507987a222025-08-20T02:54:26ZengBMJ Publishing GroupBMJ Open2044-60552020-09-0110910.1136/bmjopen-2020-038459Protocol for a systematic review on tertiary prevention interventions for patients with stroke in African countriesAdamu Addissie0Eva Johanna Kantelhardt1Thomas Frese2Eric Sven Kroeber3Lucas Adam4Alexander Bauer5Susanne Unverzagt6Department of Preventive Medicine, School of Public Health, College of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaDepartment of Gynaecology, Institute of Medical Epidemiology, Biostatistics and Informatics, Martin-Luther-Universitat Halle-Wittenberg, Halle, Saxony-Anhalt, Germany3 Institute of General Practice, Faculty of Medicine, University of Halle-Wittenberg, Halle/Saale, GermanyFaculty of Medicine, Institute of General Practice and Family Medicine, Center of Health Sciences, Martin Luther University of Halle Wittenberg, Halle (Saale), GermanyCenter of Health Sciences, Institute of General Practice and Family Medicine, Martin-Luther-Universitat Halle-Wittenberg, Halle, Sachsen-Anhalt, GermanyMedical Faculty, Institute of General Practice and Family Medicine, Center of Health Sciences, Martin Luther University Halle Wittenberg, Halle (Saale), GermanyMedical Faculty of the Martin Luther University Halle-Wittenberg, Institute of General Practice and Family Medicine, Halle, GermanyIntroduction Stroke is one of the common causes of mortality, morbidity and years of life lost worldwide. Baseline research on stroke epidemiology, prevention, acute and rehabilitative interventions in Africa is necessary to approach specific contexts and regional circumstances. Most studies on stroke have been conducted in high-income countries. This protocol describes the methodology to summarise the best available evidence on tertiary preventive strategies like rehabilitation interventions for patients with stroke in African contexts.Methods and analysis We will include experimental studies and prospective cohort studies conducted in African countries. A protocol has been registered in PROSPERO. Systematic search will include eight electronic databases (MEDLINE, Embase, the Cochrane Library, CINAHL, Cab-Direct, Physiotherapy Evidence Database (PEDro), African Journals Online and African Index Medicus) and the International Clinical Trials Register Platform and base on predefined search terms. We will search from inception of each database and repeat this strategy 3 months prior to review submission. Details of all eligible studies will be extracted and risk of bias for outcomes on global disability or dependence in daily living will be assessed. Main aim of this systematic review is to provide a narrative description of evidence on tertiary prevention strategies (including rehabilitation) for stroke. This description will be visualised in structured tables to aid interpretation of study characteristics, intervention effects and certainty of the evidence.Ethics and dissemination No ethical approval is necessary. Results will be presented in national and international conferences and published in a peer-reviewed journal.PROSPERO registration number CRD42020159125.https://bmjopen.bmj.com/content/10/9/e038459.full
spellingShingle Adamu Addissie
Eva Johanna Kantelhardt
Thomas Frese
Eric Sven Kroeber
Lucas Adam
Alexander Bauer
Susanne Unverzagt
Protocol for a systematic review on tertiary prevention interventions for patients with stroke in African countries
BMJ Open
title Protocol for a systematic review on tertiary prevention interventions for patients with stroke in African countries
title_full Protocol for a systematic review on tertiary prevention interventions for patients with stroke in African countries
title_fullStr Protocol for a systematic review on tertiary prevention interventions for patients with stroke in African countries
title_full_unstemmed Protocol for a systematic review on tertiary prevention interventions for patients with stroke in African countries
title_short Protocol for a systematic review on tertiary prevention interventions for patients with stroke in African countries
title_sort protocol for a systematic review on tertiary prevention interventions for patients with stroke in african countries
url https://bmjopen.bmj.com/content/10/9/e038459.full
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