Otolith Degeneration with Aging: Insights from Video Ocular Counter-Roll (vOCR) Assessment
Background: Vestibular assessments, such as the video ocular counter roll (vOCR) test, offer valuable insights into the interactions between age, otolith function, and vestibular performance. Objective: To analyze the relation between age and vOCR gains as a potential marker of age-related otolith d...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2025-07-01
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| Series: | Journal of Otology |
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| Online Access: | https://www.sciopen.com/article/10.26599/JOTO.2025.9540030 |
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| author | Melissa Castillo-Bustamante Jorge Madrigal Elizabeth Andalón-Dueñas Johanna Marcela Vanegas Ireri Espinoza |
| author_facet | Melissa Castillo-Bustamante Jorge Madrigal Elizabeth Andalón-Dueñas Johanna Marcela Vanegas Ireri Espinoza |
| author_sort | Melissa Castillo-Bustamante |
| collection | DOAJ |
| description | Background: Vestibular assessments, such as the video ocular counter roll (vOCR) test, offer valuable insights into the interactions between age, otolith function, and vestibular performance. Objective: To analyze the relation between age and vOCR gains as a potential marker of age-related otolith degeneration. Methods: A total of 107 participants underwent vOCR testing. Descriptive statistics and simple linear regression analyses were conducted to explore the association between age and vOCR gains. Results were presented using regression coefficients, 95% confidence intervals, p-values, and R-squared values. Results: In the overall sample, statistically significant associations were observed between age and vOCR gains in both ears. For the right ear, vOCR gains decreased with increasing age (coefficient: -0.03; 95% CI: -0.05 to -0.01; p <0.001; R² = 0.08), while the left ear showed a slightly stronger association (coefficient: -0.04; 95% CI: -0.07 to -0.02; p < 0.001; R² = 0.12). These findings indicate a moderate age-related decline in otolith-mediated vestibular responses. Conclusion: vOCR gains appear to decline with age, reflecting potential age-related otolith degeneration. These results support the clinical value of vOCR as a non-invasive method to assess vestibular function and its changes across the lifespan. |
| format | Article |
| id | doaj-art-5ffac6f1e2574b579e700ce39e11de4d |
| institution | Kabale University |
| issn | 1672-2930 2524-1753 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Journal of Otology |
| spelling | doaj-art-5ffac6f1e2574b579e700ce39e11de4d2025-08-20T03:50:49ZengTsinghua University PressJournal of Otology1672-29302524-17532025-07-0120319820310.26599/JOTO.2025.9540030Otolith Degeneration with Aging: Insights from Video Ocular Counter-Roll (vOCR) AssessmentMelissa Castillo-Bustamante0Jorge Madrigal1Elizabeth Andalón-Dueñas2Johanna Marcela Vanegas3Ireri Espinoza4School of Health Sciences, Universidad Pontificia Bolivariana, Street 1ª 70-01, Medellín, ColombiaFacultad Mexicana de Medicina, Universidad La Salle México. Ciudad de México, MéxicoCentro de Vértigo y Mareo. Guadalajara, MéxicoSchool of Health Sciences, Universidad Pontificia Bolivariana, Street 1ª 70-01, Medellín, ColombiaCentro de Vértigo y Mareo. Ciudad de México, MéxicoBackground: Vestibular assessments, such as the video ocular counter roll (vOCR) test, offer valuable insights into the interactions between age, otolith function, and vestibular performance. Objective: To analyze the relation between age and vOCR gains as a potential marker of age-related otolith degeneration. Methods: A total of 107 participants underwent vOCR testing. Descriptive statistics and simple linear regression analyses were conducted to explore the association between age and vOCR gains. Results were presented using regression coefficients, 95% confidence intervals, p-values, and R-squared values. Results: In the overall sample, statistically significant associations were observed between age and vOCR gains in both ears. For the right ear, vOCR gains decreased with increasing age (coefficient: -0.03; 95% CI: -0.05 to -0.01; p <0.001; R² = 0.08), while the left ear showed a slightly stronger association (coefficient: -0.04; 95% CI: -0.07 to -0.02; p < 0.001; R² = 0.12). These findings indicate a moderate age-related decline in otolith-mediated vestibular responses. Conclusion: vOCR gains appear to decline with age, reflecting potential age-related otolith degeneration. These results support the clinical value of vOCR as a non-invasive method to assess vestibular function and its changes across the lifespan.https://www.sciopen.com/article/10.26599/JOTO.2025.9540030otolith degenerationvideo ocular counter rollvestibular disordersvestibular testing |
| spellingShingle | Melissa Castillo-Bustamante Jorge Madrigal Elizabeth Andalón-Dueñas Johanna Marcela Vanegas Ireri Espinoza Otolith Degeneration with Aging: Insights from Video Ocular Counter-Roll (vOCR) Assessment Journal of Otology otolith degeneration video ocular counter roll vestibular disorders vestibular testing |
| title | Otolith Degeneration with Aging: Insights from Video Ocular Counter-Roll (vOCR) Assessment |
| title_full | Otolith Degeneration with Aging: Insights from Video Ocular Counter-Roll (vOCR) Assessment |
| title_fullStr | Otolith Degeneration with Aging: Insights from Video Ocular Counter-Roll (vOCR) Assessment |
| title_full_unstemmed | Otolith Degeneration with Aging: Insights from Video Ocular Counter-Roll (vOCR) Assessment |
| title_short | Otolith Degeneration with Aging: Insights from Video Ocular Counter-Roll (vOCR) Assessment |
| title_sort | otolith degeneration with aging insights from video ocular counter roll vocr assessment |
| topic | otolith degeneration video ocular counter roll vestibular disorders vestibular testing |
| url | https://www.sciopen.com/article/10.26599/JOTO.2025.9540030 |
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