Cross-talk between lactate metabolism and immunity reveals CEP55 as a potential regulator in the immunosuppressive microenvironment of hepatocellular carcinoma

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Main Authors: Jie Li, Yuyuan Zhang, Jinhai Deng, Siyuan Weng, Hui Xu, Yuhao Ba, Anning Zuo, Shutong Liu, Quan Cheng, Jian Zhang, Peng Luo, Zhen Li, Xinwei Han, Zaoqu Liu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-05-01
Series:Genes and Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S235230422400196X
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author Jie Li
Yuyuan Zhang
Jinhai Deng
Siyuan Weng
Hui Xu
Yuhao Ba
Anning Zuo
Shutong Liu
Quan Cheng
Jian Zhang
Peng Luo
Zhen Li
Xinwei Han
Zaoqu Liu
author_facet Jie Li
Yuyuan Zhang
Jinhai Deng
Siyuan Weng
Hui Xu
Yuhao Ba
Anning Zuo
Shutong Liu
Quan Cheng
Jian Zhang
Peng Luo
Zhen Li
Xinwei Han
Zaoqu Liu
author_sort Jie Li
collection DOAJ
format Article
id doaj-art-5ff1613cb5064976b85f808e85e022eb
institution DOAJ
issn 2352-3042
language English
publishDate 2025-05-01
publisher KeAi Communications Co., Ltd.
record_format Article
series Genes and Diseases
spelling doaj-art-5ff1613cb5064976b85f808e85e022eb2025-08-20T02:59:49ZengKeAi Communications Co., Ltd.Genes and Diseases2352-30422025-05-0112310139910.1016/j.gendis.2024.101399Cross-talk between lactate metabolism and immunity reveals CEP55 as a potential regulator in the immunosuppressive microenvironment of hepatocellular carcinomaJie Li0Yuyuan Zhang1Jinhai Deng2Siyuan Weng3Hui Xu4Yuhao Ba5Anning Zuo6Shutong Liu7Quan Cheng8Jian Zhang9Peng Luo10Zhen Li11Xinwei Han12Zaoqu Liu13Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, ChinaDepartment of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, ChinaRichard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London WC2R 2LS, UKDepartment of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, ChinaDepartment of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, ChinaDepartment of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, ChinaDepartment of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, ChinaDepartment of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, ChinaDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008, ChinaDepartment of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 519015, ChinaDepartment of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 519015, ChinaDepartment of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China; Corresponding author.Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China; Interventional Institute of Zhengzhou University, Zhengzhou, Henan 450052, China; Interventional Treatment and Clinical Research Center of Henan Province, Zhengzhou, Henan 450052, China; Corresponding author. Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China; Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China; Corresponding author.http://www.sciencedirect.com/science/article/pii/S235230422400196X
spellingShingle Jie Li
Yuyuan Zhang
Jinhai Deng
Siyuan Weng
Hui Xu
Yuhao Ba
Anning Zuo
Shutong Liu
Quan Cheng
Jian Zhang
Peng Luo
Zhen Li
Xinwei Han
Zaoqu Liu
Cross-talk between lactate metabolism and immunity reveals CEP55 as a potential regulator in the immunosuppressive microenvironment of hepatocellular carcinoma
Genes and Diseases
title Cross-talk between lactate metabolism and immunity reveals CEP55 as a potential regulator in the immunosuppressive microenvironment of hepatocellular carcinoma
title_full Cross-talk between lactate metabolism and immunity reveals CEP55 as a potential regulator in the immunosuppressive microenvironment of hepatocellular carcinoma
title_fullStr Cross-talk between lactate metabolism and immunity reveals CEP55 as a potential regulator in the immunosuppressive microenvironment of hepatocellular carcinoma
title_full_unstemmed Cross-talk between lactate metabolism and immunity reveals CEP55 as a potential regulator in the immunosuppressive microenvironment of hepatocellular carcinoma
title_short Cross-talk between lactate metabolism and immunity reveals CEP55 as a potential regulator in the immunosuppressive microenvironment of hepatocellular carcinoma
title_sort cross talk between lactate metabolism and immunity reveals cep55 as a potential regulator in the immunosuppressive microenvironment of hepatocellular carcinoma
url http://www.sciencedirect.com/science/article/pii/S235230422400196X
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