Effects of the replacement of fishmeal with defatted black soldier fly (Hermetia illucens) larvae meal in high lipid diets on growth, serum liver antioxidant and disease resistance in the hybrid grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂)

A previous study showed that high lipid (16 %) diet could reduce protein content from 50 % to 45 % without affecting growth performance of hybrid grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂). In this experiment, defatted black soldier fly (Hermetia illucens) larvae meal was added to the...

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Main Authors: Weibin Huang, Wanting Huang, Wenshan Cai, Hao Liu, Menglong Zhou, Beiping Tan, Hengyang Song, Xiaohui Dong
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Aquaculture Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352513425004016
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author Weibin Huang
Wanting Huang
Wenshan Cai
Hao Liu
Menglong Zhou
Beiping Tan
Hengyang Song
Xiaohui Dong
author_facet Weibin Huang
Wanting Huang
Wenshan Cai
Hao Liu
Menglong Zhou
Beiping Tan
Hengyang Song
Xiaohui Dong
author_sort Weibin Huang
collection DOAJ
description A previous study showed that high lipid (16 %) diet could reduce protein content from 50 % to 45 % without affecting growth performance of hybrid grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂). In this experiment, defatted black soldier fly (Hermetia illucens) larvae meal was added to the formula to replace fish meal (FM), in part to address the current shortage and high price of FM. The effects on growth performance, serum and liver antioxidant and immune function, liver morphology and disease resistance of grouper were investigated by replacing 0 (FM content in the control: 40 %), 20, 40, 60 and 80 % FM with defatted black soldier fly larvae meal. A total of 450 fish were included in the experiment and randomly assigned to 15 fiber tanks (1 m3) for eight weeks. The result shows that dietary FM content can be reduced to 32 % with the defatted black solider fly larvae meal as an alternative, when substitution levels continued to rise, growth performance was significantly reduced (P < 0.05). In serum, the content of IgM in DSM20 group was significantly higher than FM group (P < 0.05). T-AOC was significantly higher in DSM20 and DSM40 groups than in other groups (P < 0.05). And there was no significant difference in SOD. In liver, DSM40 group had the highest T-AOC content, which was higher than other group (P < 0.05). Compared to other groups, the FM group's IgM content was considerably reduced (P < 0.05). In addition, high levels of fish meal substitution can damage liver morphology, as well as regulate the expression levels of liver antioxidant and immune genes. In general, defatted black soldier fly larvae meal can reduce FM to 32 % without affecting its growth. Proper defatted black soldier fly larvae meal can improve the antioxidant and immunity of serum and liver.
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spelling doaj-art-5febd4eee1154e04b30def5a6948d14e2025-08-20T02:57:04ZengElsevierAquaculture Reports2352-51342025-09-014310301510.1016/j.aqrep.2025.103015Effects of the replacement of fishmeal with defatted black soldier fly (Hermetia illucens) larvae meal in high lipid diets on growth, serum liver antioxidant and disease resistance in the hybrid grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂)Weibin Huang0Wanting Huang1Wenshan Cai2Hao Liu3Menglong Zhou4Beiping Tan5Hengyang Song6Xiaohui Dong7Laboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; GuangDong Engineering Technology Research Centre of Aquatic Animals Precision Nutrition and High Efficiency Feed, Zhanjiang, Guangdong 524088, ChinaLaboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; GuangDong Engineering Technology Research Centre of Aquatic Animals Precision Nutrition and High Efficiency Feed, Zhanjiang, Guangdong 524088, ChinaLaboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; GuangDong Engineering Technology Research Centre of Aquatic Animals Precision Nutrition and High Efficiency Feed, Zhanjiang, Guangdong 524088, ChinaLaboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; GuangDong Engineering Technology Research Centre of Aquatic Animals Precision Nutrition and High Efficiency Feed, Zhanjiang, Guangdong 524088, ChinaLaboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; GuangDong Engineering Technology Research Centre of Aquatic Animals Precision Nutrition and High Efficiency Feed, Zhanjiang, Guangdong 524088, ChinaLaboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; GuangDong Engineering Technology Research Centre of Aquatic Animals Precision Nutrition and High Efficiency Feed, Zhanjiang, Guangdong 524088, ChinaLaboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; GuangDong Engineering Technology Research Centre of Aquatic Animals Precision Nutrition and High Efficiency Feed, Zhanjiang, Guangdong 524088, ChinaLaboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; GuangDong Engineering Technology Research Centre of Aquatic Animals Precision Nutrition and High Efficiency Feed, Zhanjiang, Guangdong 524088, China; Correspondence to: Laboratory of Aquatic Animal Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang 524088, China.A previous study showed that high lipid (16 %) diet could reduce protein content from 50 % to 45 % without affecting growth performance of hybrid grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂). In this experiment, defatted black soldier fly (Hermetia illucens) larvae meal was added to the formula to replace fish meal (FM), in part to address the current shortage and high price of FM. The effects on growth performance, serum and liver antioxidant and immune function, liver morphology and disease resistance of grouper were investigated by replacing 0 (FM content in the control: 40 %), 20, 40, 60 and 80 % FM with defatted black soldier fly larvae meal. A total of 450 fish were included in the experiment and randomly assigned to 15 fiber tanks (1 m3) for eight weeks. The result shows that dietary FM content can be reduced to 32 % with the defatted black solider fly larvae meal as an alternative, when substitution levels continued to rise, growth performance was significantly reduced (P < 0.05). In serum, the content of IgM in DSM20 group was significantly higher than FM group (P < 0.05). T-AOC was significantly higher in DSM20 and DSM40 groups than in other groups (P < 0.05). And there was no significant difference in SOD. In liver, DSM40 group had the highest T-AOC content, which was higher than other group (P < 0.05). Compared to other groups, the FM group's IgM content was considerably reduced (P < 0.05). In addition, high levels of fish meal substitution can damage liver morphology, as well as regulate the expression levels of liver antioxidant and immune genes. In general, defatted black soldier fly larvae meal can reduce FM to 32 % without affecting its growth. Proper defatted black soldier fly larvae meal can improve the antioxidant and immunity of serum and liver.http://www.sciencedirect.com/science/article/pii/S2352513425004016Hermetia illucensHybrid grouperImmune enzymeAntioxidant enzymeDisease resistance
spellingShingle Weibin Huang
Wanting Huang
Wenshan Cai
Hao Liu
Menglong Zhou
Beiping Tan
Hengyang Song
Xiaohui Dong
Effects of the replacement of fishmeal with defatted black soldier fly (Hermetia illucens) larvae meal in high lipid diets on growth, serum liver antioxidant and disease resistance in the hybrid grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂)
Aquaculture Reports
Hermetia illucens
Hybrid grouper
Immune enzyme
Antioxidant enzyme
Disease resistance
title Effects of the replacement of fishmeal with defatted black soldier fly (Hermetia illucens) larvae meal in high lipid diets on growth, serum liver antioxidant and disease resistance in the hybrid grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂)
title_full Effects of the replacement of fishmeal with defatted black soldier fly (Hermetia illucens) larvae meal in high lipid diets on growth, serum liver antioxidant and disease resistance in the hybrid grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂)
title_fullStr Effects of the replacement of fishmeal with defatted black soldier fly (Hermetia illucens) larvae meal in high lipid diets on growth, serum liver antioxidant and disease resistance in the hybrid grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂)
title_full_unstemmed Effects of the replacement of fishmeal with defatted black soldier fly (Hermetia illucens) larvae meal in high lipid diets on growth, serum liver antioxidant and disease resistance in the hybrid grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂)
title_short Effects of the replacement of fishmeal with defatted black soldier fly (Hermetia illucens) larvae meal in high lipid diets on growth, serum liver antioxidant and disease resistance in the hybrid grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂)
title_sort effects of the replacement of fishmeal with defatted black soldier fly hermetia illucens larvae meal in high lipid diets on growth serum liver antioxidant and disease resistance in the hybrid grouper epinephelus fuscoguttatus ♀ e lanceolatus ♂
topic Hermetia illucens
Hybrid grouper
Immune enzyme
Antioxidant enzyme
Disease resistance
url http://www.sciencedirect.com/science/article/pii/S2352513425004016
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