Therapeutic efficacy of artemether–lumefantrine in North-Eastern states of India and prevalence of drug resistance-associated molecular markers

Therapeutic efficacy of artemether–lumefantrine in North-Eastern states of India and prevalence of drug resistance-associated molecular markers

Abstract Background Plasmodium falciparum is the main cause of malaria in North-Eastern (NE) states of India. Artemether–lumefantrine (AL) was introduced as first-line therapy against uncomplicated P. falciparum cases in 2013 after the emergence of resistance to sulfadoxine–pyrimethamine. The aim of...

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Main Authors: Shreelekha Dutta, Sri Krishna, Anup Kumar Vishwakarma, Sweta Mishra, Sushrikanta Khandai, Disphikha Goswami, Soni Kumari, Nazia Ali, Anil Kumar Verma, Kuldeep Singh, Aparup Das, Anup R. Anvikar, Praveen Kumar Bharti
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Malaria Journal
Subjects:
Therapeutic efficacy
Artemether–lumefantrine
Antimalarial drug resistance
Molecular monitoring
North-East India
Online Access:https://doi.org/10.1186/s12936-025-05338-1
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