A Rare Occurrence of Three Primary Malignancies of the Rectum, Breast, and Kidney in the Same Patient: A Case Report and Review of the Literature
An increasing number of patients with multiple primary cancers are encountered due to improved cancer detection, widespread cancer screening, and better cancer treatment. Here, we report such a patient without a family history of malignancies or a known genetic predisposition developing three primar...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2019/1716029 |
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| author | Umesh Jayarajah Oshan Basnayake Pradeep Wijerathne Jayan Jayasinghe Dharmabandhu N. Samarasekera Sanjeewa Seneviratne |
| author_facet | Umesh Jayarajah Oshan Basnayake Pradeep Wijerathne Jayan Jayasinghe Dharmabandhu N. Samarasekera Sanjeewa Seneviratne |
| author_sort | Umesh Jayarajah |
| collection | DOAJ |
| description | An increasing number of patients with multiple primary cancers are encountered due to improved cancer detection, widespread cancer screening, and better cancer treatment. Here, we report such a patient without a family history of malignancies or a known genetic predisposition developing three primary malignancies of the rectum, breast, and kidney. A 63-year-old female who underwent an anterior resection for rectal cancer was detected to have an elevated carcinoembryonic antigen (CEA) level during a routine follow-up, 8 years after the initial surgery. Clinical examination revealed a left breast lump which was confirmed as invasive ductal carcinoma (pT3 pN0 cM0). Imaging and colonoscopy excluded a local recurrence. However, a right renal lesion suggestive of a renal cell carcinoma was detected (pT1a). She underwent left mastectomy with a sentinel lymph node biopsy and a right partial nephrectomy with a curative intent. Postoperatively, CEA levels declined to normal limits. Management of multiple primary malignancies poses a major challenge. A multidisciplinary approach and tailored decision-making for the individual patient help with the optimum outcome. |
| format | Article |
| id | doaj-art-5fd7a078a54e45a4ae7bd909cace643c |
| institution | OA Journals |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-5fd7a078a54e45a4ae7bd909cace643c2025-08-20T02:24:00ZengWileyCase Reports in Surgery2090-69002090-69192019-01-01201910.1155/2019/17160291716029A Rare Occurrence of Three Primary Malignancies of the Rectum, Breast, and Kidney in the Same Patient: A Case Report and Review of the LiteratureUmesh Jayarajah0Oshan Basnayake1Pradeep Wijerathne2Jayan Jayasinghe3Dharmabandhu N. Samarasekera4Sanjeewa Seneviratne5Professorial Surgical Unit, National Hospital of Sri Lanka, Colombo, Sri LankaProfessorial Surgical Unit, National Hospital of Sri Lanka, Colombo, Sri LankaProfessorial Surgical Unit, National Hospital of Sri Lanka, Colombo, Sri LankaProfessorial Surgical Unit, National Hospital of Sri Lanka, Colombo, Sri LankaDepartment of Surgery, Faculty of Medicine, University of Colombo, Sri LankaDepartment of Surgery, Faculty of Medicine, University of Colombo, Sri LankaAn increasing number of patients with multiple primary cancers are encountered due to improved cancer detection, widespread cancer screening, and better cancer treatment. Here, we report such a patient without a family history of malignancies or a known genetic predisposition developing three primary malignancies of the rectum, breast, and kidney. A 63-year-old female who underwent an anterior resection for rectal cancer was detected to have an elevated carcinoembryonic antigen (CEA) level during a routine follow-up, 8 years after the initial surgery. Clinical examination revealed a left breast lump which was confirmed as invasive ductal carcinoma (pT3 pN0 cM0). Imaging and colonoscopy excluded a local recurrence. However, a right renal lesion suggestive of a renal cell carcinoma was detected (pT1a). She underwent left mastectomy with a sentinel lymph node biopsy and a right partial nephrectomy with a curative intent. Postoperatively, CEA levels declined to normal limits. Management of multiple primary malignancies poses a major challenge. A multidisciplinary approach and tailored decision-making for the individual patient help with the optimum outcome.http://dx.doi.org/10.1155/2019/1716029 |
| spellingShingle | Umesh Jayarajah Oshan Basnayake Pradeep Wijerathne Jayan Jayasinghe Dharmabandhu N. Samarasekera Sanjeewa Seneviratne A Rare Occurrence of Three Primary Malignancies of the Rectum, Breast, and Kidney in the Same Patient: A Case Report and Review of the Literature Case Reports in Surgery |
| title | A Rare Occurrence of Three Primary Malignancies of the Rectum, Breast, and Kidney in the Same Patient: A Case Report and Review of the Literature |
| title_full | A Rare Occurrence of Three Primary Malignancies of the Rectum, Breast, and Kidney in the Same Patient: A Case Report and Review of the Literature |
| title_fullStr | A Rare Occurrence of Three Primary Malignancies of the Rectum, Breast, and Kidney in the Same Patient: A Case Report and Review of the Literature |
| title_full_unstemmed | A Rare Occurrence of Three Primary Malignancies of the Rectum, Breast, and Kidney in the Same Patient: A Case Report and Review of the Literature |
| title_short | A Rare Occurrence of Three Primary Malignancies of the Rectum, Breast, and Kidney in the Same Patient: A Case Report and Review of the Literature |
| title_sort | rare occurrence of three primary malignancies of the rectum breast and kidney in the same patient a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2019/1716029 |
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