The soil-plant-human gut microbiome axis into perspective
Abstract Microbiomes of soil, plants, and the animal gut are pivotal for key life processes such as nutrient cycling, stress resilience, and immunity. While studies have hinted at a shared microbial reservoir connecting these environments, compelling evidence of a soil-plant-gut microbiome axis is s...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-62989-z |
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| author | Haikun Ma Deborah Cornadó Jos M. Raaijmakers |
| author_facet | Haikun Ma Deborah Cornadó Jos M. Raaijmakers |
| author_sort | Haikun Ma |
| collection | DOAJ |
| description | Abstract Microbiomes of soil, plants, and the animal gut are pivotal for key life processes such as nutrient cycling, stress resilience, and immunity. While studies have hinted at a shared microbial reservoir connecting these environments, compelling evidence of a soil-plant-gut microbiome axis is scarce. This perspective explores the potential continuum and diversification of microbes along this axis, highlighting specific microorganisms capable of moving from soil to plants to the human gut. A conceptual framework is proposed to better understand the mechanisms driving interactions among these microbiomes. We also examine how soil, plant, and gut microbiomes may co-evolve and influence one another through reciprocal effects. We consider external environmental factors that could strengthen their interconnections, potentially creating beneficial feedback loops that impact ecosystem and human health. |
| format | Article |
| id | doaj-art-5fd5f5eb17a14696bf51753deadb1073 |
| institution | Kabale University |
| issn | 2041-1723 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-5fd5f5eb17a14696bf51753deadb10732025-08-24T11:37:33ZengNature PortfolioNature Communications2041-17232025-08-0116111210.1038/s41467-025-62989-zThe soil-plant-human gut microbiome axis into perspectiveHaikun Ma0Deborah Cornadó1Jos M. Raaijmakers2State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai UniversityDepartment of Microbial Ecology, Netherlands Institute of Ecology (NIOO-KNAW)Department of Microbial Ecology, Netherlands Institute of Ecology (NIOO-KNAW)Abstract Microbiomes of soil, plants, and the animal gut are pivotal for key life processes such as nutrient cycling, stress resilience, and immunity. While studies have hinted at a shared microbial reservoir connecting these environments, compelling evidence of a soil-plant-gut microbiome axis is scarce. This perspective explores the potential continuum and diversification of microbes along this axis, highlighting specific microorganisms capable of moving from soil to plants to the human gut. A conceptual framework is proposed to better understand the mechanisms driving interactions among these microbiomes. We also examine how soil, plant, and gut microbiomes may co-evolve and influence one another through reciprocal effects. We consider external environmental factors that could strengthen their interconnections, potentially creating beneficial feedback loops that impact ecosystem and human health.https://doi.org/10.1038/s41467-025-62989-z |
| spellingShingle | Haikun Ma Deborah Cornadó Jos M. Raaijmakers The soil-plant-human gut microbiome axis into perspective Nature Communications |
| title | The soil-plant-human gut microbiome axis into perspective |
| title_full | The soil-plant-human gut microbiome axis into perspective |
| title_fullStr | The soil-plant-human gut microbiome axis into perspective |
| title_full_unstemmed | The soil-plant-human gut microbiome axis into perspective |
| title_short | The soil-plant-human gut microbiome axis into perspective |
| title_sort | soil plant human gut microbiome axis into perspective |
| url | https://doi.org/10.1038/s41467-025-62989-z |
| work_keys_str_mv | AT haikunma thesoilplanthumangutmicrobiomeaxisintoperspective AT deborahcornado thesoilplanthumangutmicrobiomeaxisintoperspective AT josmraaijmakers thesoilplanthumangutmicrobiomeaxisintoperspective AT haikunma soilplanthumangutmicrobiomeaxisintoperspective AT deborahcornado soilplanthumangutmicrobiomeaxisintoperspective AT josmraaijmakers soilplanthumangutmicrobiomeaxisintoperspective |