Results of the 2023 rapid DNA multi-laboratory study – I-Chip
Identical sensitivity and mixture sample sets were provided to six external laboratories to evaluate the recent enhancements to the Rapid DNA technology for crime scene-type samples. Data were returned to the Federal Bureau of Investigation and the National Institute of Standards and Technology for...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-12-01
|
| Series: | Forensic Science International: Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2665910724000446 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850250231342432256 |
|---|---|
| author | Erica L. Romsos Lilliana I. Moreno Douglas R. Hares |
| author_facet | Erica L. Romsos Lilliana I. Moreno Douglas R. Hares |
| author_sort | Erica L. Romsos |
| collection | DOAJ |
| description | Identical sensitivity and mixture sample sets were provided to six external laboratories to evaluate the recent enhancements to the Rapid DNA technology for crime scene-type samples. Data were returned to the Federal Bureau of Investigation and the National Institute of Standards and Technology for review and analysis. Manual interpretation (modified Rapid DNA analysis) was conducted on all samples to assess the success of genotyping for both full profiles and the 20 Combined DNA Index System (CODIS) core STR loci using 18 total cellular DNA input amounts ranging from 102.4 ng to 0.025 ng. Two-person and three-person mixtures at varying ratios for two total DNA inputs were analyzed and observed allele percentages were compared to expected allele percentages. |
| format | Article |
| id | doaj-art-5fd349975b8e43e3beb587258ea7d3e0 |
| institution | OA Journals |
| issn | 2665-9107 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Forensic Science International: Reports |
| spelling | doaj-art-5fd349975b8e43e3beb587258ea7d3e02025-08-20T01:58:16ZengElsevierForensic Science International: Reports2665-91072024-12-011010039510.1016/j.fsir.2024.100395Results of the 2023 rapid DNA multi-laboratory study – I-ChipErica L. Romsos0Lilliana I. Moreno1Douglas R. Hares2Applied Genetics Group, National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, MD 20899-8314, USA; Corresponding author.FBI Laboratory, 2501 Investigation Parkway, Quantico, VA 22135, USAFBI Laboratory, 2501 Investigation Parkway, Quantico, VA 22135, USAIdentical sensitivity and mixture sample sets were provided to six external laboratories to evaluate the recent enhancements to the Rapid DNA technology for crime scene-type samples. Data were returned to the Federal Bureau of Investigation and the National Institute of Standards and Technology for review and analysis. Manual interpretation (modified Rapid DNA analysis) was conducted on all samples to assess the success of genotyping for both full profiles and the 20 Combined DNA Index System (CODIS) core STR loci using 18 total cellular DNA input amounts ranging from 102.4 ng to 0.025 ng. Two-person and three-person mixtures at varying ratios for two total DNA inputs were analyzed and observed allele percentages were compared to expected allele percentages.http://www.sciencedirect.com/science/article/pii/S2665910724000446Rapid DNAModified rapid DNA analysisANDE 6 CFlexPlex |
| spellingShingle | Erica L. Romsos Lilliana I. Moreno Douglas R. Hares Results of the 2023 rapid DNA multi-laboratory study – I-Chip Forensic Science International: Reports Rapid DNA Modified rapid DNA analysis ANDE 6 C FlexPlex |
| title | Results of the 2023 rapid DNA multi-laboratory study – I-Chip |
| title_full | Results of the 2023 rapid DNA multi-laboratory study – I-Chip |
| title_fullStr | Results of the 2023 rapid DNA multi-laboratory study – I-Chip |
| title_full_unstemmed | Results of the 2023 rapid DNA multi-laboratory study – I-Chip |
| title_short | Results of the 2023 rapid DNA multi-laboratory study – I-Chip |
| title_sort | results of the 2023 rapid dna multi laboratory study i chip |
| topic | Rapid DNA Modified rapid DNA analysis ANDE 6 C FlexPlex |
| url | http://www.sciencedirect.com/science/article/pii/S2665910724000446 |
| work_keys_str_mv | AT ericalromsos resultsofthe2023rapiddnamultilaboratorystudyichip AT lillianaimoreno resultsofthe2023rapiddnamultilaboratorystudyichip AT douglasrhares resultsofthe2023rapiddnamultilaboratorystudyichip |