Development of an in vivo RNAi protocol to investigate gene function in the filarial nematode, Brugia malayi.
Our ability to control diseases caused by parasitic nematodes is constrained by a limited portfolio of effective drugs and a paucity of robust tools to investigate parasitic nematode biology. RNA interference (RNAi) is a reverse-genetics tool with great potential to identify novel drug targets and i...
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| Main Authors: | Chuanzhe Song, Jack M Gallup, Tim A Day, Lyric C Bartholomay, Michael J Kimber |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-12-01
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| Series: | PLoS Pathogens |
| Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1001239&type=printable |
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